Results 21 to 30 of about 95,661 (297)

Biotransformation of Isoflavone Using Enzymatic Reactions

Molecules, 2013
The roles of cytochrome P450 monooxygenases (CYPs) from Streptomyces spp. which are called the “treasure islands” for natural products for medicine and antibiotics are not well understood.
Changhyun Roh
doaj   +1 more source

Designed whole-cell-catalysis-assisted synthesis of 9,11-secosterols

Beilstein Journal of Organic Chemistry, 2021
A method for the synthesis of 9,11-secosteroids starting from the natural corticosteroid cortisol is described. There are two key steps in this approach, combining chemistry and synthetic biology.
Marek Kõllo, Marje Kasari, Villu Kasari, Tõnis Pehk, Ivar Järving, Margus Lopp, Arvi Jõers, Tõnis Kanger   +7 more
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Conversion of Unsaturated Short- to Medium-Chain Fatty Acids by Unspecific Peroxygenases (UPOs)

Applied Microbiology, 2023
Eighteen short- to medium-chain monounsaturated fatty acids were screened for hydroxylation and epoxidation using eleven different peroxygenase preparations.
Alexander Karich, Fabian Salzsieder, Martin Kluge, Miguel Alcalde, René Ullrich, Martin Hofrichter   +5 more
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Efficient hydroxylation of flavonoids by using whole-cell P450 sca-2 biocatalyst in Escherichia coli

Frontiers in Bioengineering and Biotechnology, 2023
The hydroxylation is an important way to generate the functionalized derivatives of flavonoids. However, the efficient hydroxylation of flavonoids by bacterial P450 enzymes is rarely reported.
Baodong Hu, Baodong Hu, Baodong Hu, Baodong Hu, Xinrui Zhao, Xinrui Zhao, Xinrui Zhao, Xinrui Zhao, Jingwen Zhou, Jingwen Zhou, Jingwen Zhou, Jingwen Zhou, Jianghua Li, Jianghua Li, Jianghua Li, Jianghua Li, Jian Chen, Jian Chen, Jian Chen, Jian Chen, Guocheng Du, Guocheng Du, Guocheng Du, Guocheng Du, Guocheng Du   +24 more
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Biocatalytic hydroxylation of n-butane with in situ cofactor regeneration at low temperature and under normal pressure

Beilstein Journal of Organic Chemistry, 2012
The hydroxylation of n-alkanes, which proceeds in the presence of a P450-monooxygenase advantageously at temperatures significantly below room temperature, is described.
Svenja Staudt, Christina A. Müller, Jan Marienhagen, Christian Böing, Stefan Buchholz, Ulrich Schwaneberg, Harald Gröger   +6 more
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A Novel Antimalarial Metabolite in Erythrocyte From the Hydroxylation of Dihydroartemisinin by Cunninghamella elegans

Frontiers in Chemistry, 2022
Dihydroartemisinin (DHA) is a sesquiterpene endoperoxide with prominent antimalarial efficacy, which was discovered by Professor Youyou Tu through the reduction of artemisinin in the 1970s.
Yue Bai, Yifan Zhao, Xinna Gao, Dong Zhang, Yue Ma, Lan Yang, Peng Sun   +6 more
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Hydroxylation Kinetics of Epoxidized Tung Oil Using Methanol as Nucleophilic Agent

International Journal of Technology, 2023
The synthesis of vegetable oil-based polyols has been carried out through the epoxidation-hydroxylation process. However, Tung oil has never been explored in the process, even though Tung oil has a high double bond.
Eni Budiyati, Rochmadi, Arief Budiman, Budhijanto   +3 more
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Recent Advances and Challenges in the Production of Hydroxylated Natural Products Using Microorganisms

Fermentation
Hydroxylation reaction is a significant source of structural diversity in natural products (NPs), playing a crucial role in improving the bioactivity, solubility, and stability of natural product molecules.
Chang Sun, Rumei Zeng, Tianpeng Chen, Yibing Yang, Yi Song, Qiang Li, Jie Cheng, Bingliang Liu   +7 more
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Regio- and stereoselective oxidation of unactivated C–H bonds with Rhodococcus rhodochrous

Beilstein Journal of Organic Chemistry, 2012
The ability of Rhodococcus rhodochrous (NCIMB 9703) to catalyse the regio- and stereoselective hydroxylation of a range of benzyloxy-substituted heterocycles has been investigated.
Elaine O’Reilly, Suzanne J. Aitken, Gideon Grogan, Paul P. Kelly, Nicholas J. Turner, Sabine L. Flitsch   +5 more
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Microbiological hydroxylation in the drimane series

, 1992
The Products of the microbiological hydroxylation of drimenol and related compounds by Mucor plumbeus and Rhizopus arrhizus were investigated.
Manuel Cortes, LECLAIRE, M, LOPEZ, J, AZERAD, R, CORTES, M, RAMIREZ, H, Isabelle Facon, ARANDA, G, Jean-Yves Lallemand, FACON, I, Robert Azerad, Jose Lopez, LALLEMAND, JY, Hector Ramirez, Gérard Aranda, Massoumée Leclaire   +15 more
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