Results 21 to 30 of about 97,747 (236)

Post-translational hydroxylation by 2OG/Fe(II)-dependent oxygenases as a novel regulatory mechanism in bacteria

open access: yesFrontiers in Microbiology, 2015
Protein hydroxylation has been well-studied in eukaryotic systems. The structural importance of hydroxylation of specific proline and lysine residues during collagen biosynthesis is well established while, recently, key roles for post-translational ...
Laura M van Staalduinen, Zongchao eJia
doaj   +1 more source

HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O2 Sensing

open access: yesScience, 2001
HIF (hypoxia-inducible factor) is a transcription factor that plays a pivotal role in cellular adaptation to changes in oxygen availability. In the presence of oxygen, HIF is targeted for destruction by an E3 ubiquitin ligase containing the von Hippel ...
M. Ivan   +9 more
semanticscholar   +1 more source

Polimerik Linoleik Asit İçeren Graft Kopolimerlerin Atom Transfer Radikal Polimerizasyonu ve Kondenzasyon Reaksiyonu ile Sentezi ve Karakterizasyonu

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi, 2021
Bu çalışmada, NPLina1-g-PCL-g-PSt üç bloklu graft kopolimerler Atom Transfer Radikal Polimerizasyonu (ATRP) ve kondenzasyon reaksiyonu kullanılarak bir basamakta tek kap (one-pot) yöntemiyle sentezlendi.
Sema Allı
doaj   +1 more source

Prediction and analysis of protein hydroxyproline and hydroxylysine.

open access: yesPLoS ONE, 2010
BackgroundHydroxylation is an important post-translational modification and closely related to various diseases. Besides the biotechnology experiments, in silico prediction methods are alternative ways to identify the potential hydroxylation sites ...
Le-Le Hu   +5 more
doaj   +1 more source

Computational Insight Into Vitamin K1 ω-Hydroxylation by Cytochrome P450 4F2

open access: yesFrontiers in Pharmacology, 2018
Vitamin K1 (VK1) plays an important role in the modulation of bleeding disorders. It has been reported that ω-hydroxylation on the VK1 aliphatic chain is catalyzed by cytochrome P450 4F2 (CYP4F2), an enzyme responsible for the metabolism of eicosanoids ...
Junhao Li   +6 more
doaj   +1 more source

Modeling of hydrogen and hydroxyl group migration on graphene [PDF]

open access: yesPhysical Chemistry Chemical Physics 12:15367-15371 (2010), 2010
Density functional calculations of optimized geometries for the migration of single hydrogen and hydroxyl groups on graphene are performed. It is shown that the migration energy barrier for the hydroxyl group is three times larger than for hydrogen. Crucial role of supercell size for the values of the migration barriers are discussed.
arxiv   +1 more source

Unraveling the Photocatalytic Mechanisms on TiO2 Surfaces Using the Oxygen-18 Isotopic Label Technique

open access: yesMolecules, 2014
During the last several decades TiO2 photocatalytic oxidation using the molecular oxygen in air has emerged as a promising method for the degradation of recalcitrant organic pollutants and selective transformations of valuable organic chemicals.
Xibin Pang   +5 more
doaj   +1 more source

Fluorescent Bis(guanidine) Copper Complexes as Precursors for Hydroxylation Catalysis

open access: yesInorganics, 2018
Bis(guanidine) copper complexes are known for their ability to activate dioxygen. Unfortunately, until now, no bis(guanidine) copper-dioxygen adduct has been able to transfer oxygen to substrates.
Florian Strassl   +8 more
doaj   +1 more source

Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?

open access: yesCells, 2019
All metazoans that utilize molecular oxygen (O2) for metabolic purposes have the capacity to adapt to hypoxia, the condition that arises when O2 demand exceeds supply. This is mediated through activation of the hypoxia-inducible factor (HIF) pathway.
Moritz J. Strowitzki   +2 more
semanticscholar   +1 more source

Hydroxylation of Rutile TiO$_2$ (110) Surface Enhancing Its Reducing Power for Photocatalysis [PDF]

open access: yesThe Journal of Physical Chemistry C 119, 1451-1456 (2015), 2015
Hydroxylation of the rutile TiO$_2$ (110) surface has attracted much attention as the excess unpaired electrons introduced by hydroxyls play a critical role in surface chemistry and photocatalysis process of this material. In this work, based on density functional theory calculations with the Hubbard U correction, the electronic structures of the ...
arxiv   +1 more source

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