Results 31 to 40 of about 97,747 (236)
Molecules, 2019 9α-Hydroxy-4-androstene-3,17-dione (9-OH-AD) is one of the significant intermediates for the preparation of β-methasone, dexamethasone, and other steroids. In general, the key enzyme that enables the biotransformation of 4-androstene-3,17-dione
Xian Zhang +10 more
doaj +1 more source
Bayesian Estimation of the Hydroxyl Radical Diffusion Coefficient at Low Temperature and High Pressure from Atomistic Molecular Dynamics [PDF]
, 2021 The hydroxyl radical is the primary reactive oxygen species produced by the radiolysis of water, and is a significant source of radiation damage to living organisms. Mobility of the hydroxyl radical at low temperatures and/or high pressures is hence a potentially important factor in determining the challenges facing psychrophilic and/or barophilic ...
arxiv +1 more source
Modulation of TRP Channel Activity by Hydroxylation and Its Therapeutic Potential
Pharmaceuticals, 2017 Two transient receptor potential (TRP) channels—TRPA1 and TRPV3—are post-translationally hydroxylated, resulting in oxygen-dependent regulation of channel activity.
Yagnesh Nagarajan +2 more
doaj +1 more source
Dynamics and fragmentation mechanism of (CH3-C5H4)Pt(CH3)3 on SiO2 Surfaces [PDF]
Beilstein Journal of Nanotechnolgy 2018, 9, 711, 2017 The interaction of (CH3-C5H4)Pt(CH3)3 ((methylcyclopentadienyl)trimethylplatinum)) molecules on fully and partially hydroxylated SiO2 surfaces, as well as the dynamics of this interaction were investigated using density functional theory (DFT) and finite temperature DFT-based molecular dynamics simulations.
arxiv +1 more source
Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates
eLife, 2019 Human and other animal cells deploy three closely related dioxygenases (PHD 1, 2 and 3) to signal oxygen levels by catalysing oxygen regulated prolyl hydroxylation of the transcription factor HIF. The discovery of the HIF prolyl-hydroxylase (PHD) enzymes
Matthew E Cockman +10 more
doaj +1 more source
Role of prolyl hydroxylation in the molecular interactions of collagens
Essays in Biochemistry, 2019 Co- and post-translational hydroxylation of proline residues is critical for the stability of the triple helical collagen structure. In this review, we summarise the biology of collagen prolyl 4-hydroxylases and collagen prolyl 3-hydroxylases, the ...
P. Rappu +3 more
semanticscholar +1 more source
Frontiers in Plant Science, 2022 Scots pine heartwood is known to have resistance to wood decay due to the presence of extractives, namely stilbenes and resin acids. However, previous studies have indicated that these extractives are degradable by wood decaying fungi.
Tiina Belt +3 more
doaj +1 more source
The effect of hydroxyl on dye-sensitized solar cells assembled with TiO2 nanorods [PDF]
Chinese Physics B, 2018, 2017 TiO2 nanorods have been prepared on ITO substrates by dc reactive magnetron sputtering technique. The hydroxyl groups have been introduced on the nanorods surface. The structure and the optical properties of these nanorods have been studied. The dye-sensitized solar cells (DSSCs) have been assembled using these TiO2 nanorods as photoelectrode.
arxiv +1 more source
Molecules, 2023 In humans, tetrahydrobiopterin (H4Bip) is the cofactor of several essential hydroxylation reactions which dysfunction cause very serious diseases at any age.
Ayoub Boulghobra +7 more
doaj +1 more source
Recent Advances in the Hydroxylation of Amino Acids and Its Derivatives
Fermentation, 2023 Hydroxy amino acids (HAAs) are of unique value in the chemical and pharmaceutical industry with antiviral, antifungal, antibacterial, and anticancer properties.
Bangxu Wang +6 more
doaj +1 more source