9-Norlignans: Occurrence, Properties and Their Semisynthetic Preparation from Hydroxymatairesinol [PDF]
Molecules, 2019 Lignans, neolignans, norlignans and norneolignans constitute a large class of phenolic natural compounds. 9-Norlignans, here defined to contain a β–β’ bond between the two phenylpropanoid units and to lack carbon number 9 from the ...
Patrik Eklund, Jan-Erik Raitanen
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Iron Absorption in Celiac Disease and Nutraceutical Effect of 7-Hydroxymatairesinol. Mini-Review [PDF]
Molecules, 2020 Anemia is the main extra-gastrointestinal symptom in inflammatory bowel diseases (IBDs). Interleukin-6 (IL-6) and other cytokines are secreted and act in the microenvironment of the small intestine mucous membrane of IBD patients.
Isabella Zanella +3 more
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Convenient Preparation and Spectroscopic Characterization of 7R-Hydroxymatairesinol [PDF]
Molecules, 2021 The preparation of 7R-HMR (allo-hydroxymatairesinol) is reported by: (a) NaBH4 kinetic reduction of 7R/7S diastereomeric mixture; and (b) epimerization of the C7 hydroxyl group by Mitsunobu reaction and subsequent ester hydrolysis.
Eleonora Colombo +3 more
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Analysis of Softwood Lignans by Comprehensive Two-Dimensional Liquid Chromatography [PDF]
Molecules, 2023 Lignans constitute a large group of phenolic plant secondary metabolites possessing high bioactivity. Their accurate determination in plant extracts with a complex chemical composition is challenging and requires advanced separation techniques.
Danil I. Falev +5 more
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Lignans in Knotwood of Norway Spruce: Localisation with Soft X-ray Microscopy and Scanning Transmission Electron Microscopy with Energy Dispersive X-ray Spectroscopy [PDF]
Molecules, 2020 Lignans are bioactive compounds that are especially abundant in the Norway spruce (Picea abies L. Karst.) knotwood. By combining a variety of chromatographic, spectroscopic and imaging techniques, we were able to quantify, qualify and localise the easily
Tuomas Mansikkala +11 more
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Formation of Tetrahydrofurano-, Aryltetralin, and Butyrolactone Norlignans through the Epoxidation of 9-Norlignans [PDF]
Molecules, 2020 Epoxidation of the C=C double bond in unsaturated norlignans derived from hydroxymatairesinol was studied. The intermediate epoxides were formed in up to quantitative conversions and were readily further transformed into tetrahydrofuran, aryltetralin ...
Patrik A. Runeberg +2 more
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The influence of lignans on the quality of life of women of perimenopausal age [PDF]
Гинекология, 2018 Problems associated with the state of health of women in the second half of her life are one of the priorities of modern medicine. The aim of the study was to determine the efficacy and safety of the drug in comparison with placebo in patients of ...
K G Serebrennikova, N A Arutyunyan
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Lignans Extract from Knotwood of Norway Spruce—A Possible New Weapon against GTDs
Journal of Fungi, 2022 Grapevine trunk diseases (GTDs) pose a major threat to the wine industry worldwide. Currently, efficient biological methods or chemical compounds are not available for the treatment of infected grapevines.
Milan Špetík +7 more
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Antimicrobial Activity of Hydroxymatairesinol (HMR) Lignan
Iraqi Journal of Pharmaceutical Sciences, 2017 Lignans are natural products widely distributed in the plant kingdom. They are composed of two β-β-linked phenylpropane (shikimate-derived biogenetic subunits).
Widad M.K. Al-Ani, Fitua M. Aziz
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Акушерство, гинекология и репродукция, 2023 Introduction. Establishing the effects of anticancer drugs on the transcriptome is an important procedure in postgenomic pharmacology necessary to comprehensively assess the desired and undesirable effects of candidate drugs.
I. Yu. Torshin +2 more
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