Lignan 7-hydroxymatairesinol in the context of post-genomic pharmacology [PDF]
ФармакоэкономикаObjective: to determine the molecular mechanisms of action of 7-hydroxymatairesinol (7(OH)MR), the main lignan of spruce extracts, characterized by oncoprotective and anti-inflammatory properties.Material and methods.
А. N. Rubashkina +3 more
doaj +3 more sources
Screening Analyses of Pinosylvin Stilbenes, Resin Acids and Lignans in Norwegian Conifers [PDF]
Molecules, 2006 The content and distribution of stilbenes and resin acids in Scots pine (Pinus sylvestris) and spruce (Picea abies), sampled in central Norway, have been examined. The contents of pinosylvin stilbenes in pine heartwood/living knots were 0.2-2/2-8 % (w/w).
Anne Fiksdahl +3 more
doaj +4 more sources
Pharmacoinformational, basic and clinical studies of 7-hydroxymatairesinol in the context of searching for effective and safe therapeutic approaches to the treatment of mastopathy [PDF]
Фармакокинетика и Фармакодинамика7-hydroxymatairesinol (7(OH)MR) is the main lignan of spruce extracts, characterized by oncoprotective and anti-inflammatory properties. The results of chemoreactome modeling made it possible to formulate the molecular mechanisms of the pharmacological ...
А. N. Rubashkina +2 more
doaj +3 more sources
Chemical Profiling, Pharmacological Activities, and Toxicity Assessment of <i>Juniperus phoenicea</i> sp. <i>turbinata</i> L. Extract: Integrated In Vitro, In Vivo, and In Silico Insights. [PDF]
Food Sci NutrHydroethanolic leaf and fruit extracts of Juniperus phoenicea showed high phenolic content, dominated by ferulic acid. Both extracts were non‐toxic and exhibited strong anti‐inflammatory, analgesic, antioxidant, and antimicrobial activities. Molecular docking confirmed stable binding to key inflammatory and microbial targets, supporting its ...
Chelouati T +13 more
europepmc +2 more sources
Sample Preparation and Separation of Lignans by Liquid Chromatography. [PDF]
J Sep SciABSTRACT Lignans are important phytochemicals found mostly in the resins of coniferous trees, but are also introduced into human diets through foods such as sesame seeds and extra‐virgin olive oil. They are pharmacologically interesting mainly because of their antioxidant activities, and they have also been shown to have cytotoxic and antimicrobial ...
Paloluoto M, Wiedmer SK.
europepmc +2 more sources
Antiparasitic Potential of Bioactive Compounds From <i>Punica granatum</i>: Preventive and Therapeutic Effects. [PDF]
J Parasitol ResDiseases caused by parasites are a global public health problem. Due to their heterogeneity and diversity, they can affect various hosts, and some diseases are considered zoonotic. Therapeutic control in parasitic diseases has lost its effectiveness over the last decades.
Vargas-Villanueva JR +4 more
europepmc +2 more sources
A New Lariciresinol-Type Butyrolactone Lignan Derived from Hydroxymatairesinol and Its Identification in Spruce Wood [PDF]
, 2016 When the natural lignan hydroxymatairesinol (1) was treated with an alkaline aqueous solution, it partially rearranged to isomeric forms of a lariciresinol-type butyrolactone lignan.
Annika I. Smeds (1726909) +5 more
core +3 more sources
Phytobioactive compounds as therapeutic agents for human diseases: A review
Food Science &Nutrition, Volume 11, Issue 6, Page 2500-2529, June 2023., 2023 Phytobioactive compounds are plant secondary metabolites and have remarkable therapeutic potential. Polyphenols, alkaloids, terpenes, and polysaccharides isolated from medicinal plants showed remarkable antioxidant, anticancer, cytotoxic, anti‐inflammatory, cardioprotective, hepatoprotective, immunomodulatory, neuroprotective, and antidiabetic ...
Muhammad Riaz +10 more
wiley +1 more source
Phenolic Compounds: From Traditional Uses to Innovative Applications and Everything in Between. [PDF]
Mol Nutr Food ResThis review deals with many aspects related to the study of phenolic compounds, starting with advances in extraction, detection, and quantification methods, going through bioavailability, bioactivity, and beneficial health properties, and discussing antioxidant and antimicrobial uses and mechanisms.
da Cunha MSB +5 more
europepmc +2 more sources
The role of 7-hydroxymatairezinol in modulation of estrogen metabolism and therapy for mastopathy [PDF]
Гинекология, 2020 Quantitative estimates of the effect of 7-hydroxymatairesinol (7-HMR) intake on estrogen balance and clinical aspects of the course of fibrocystic mastopathy have been carried out. Aim.
Anna N. Rubashkina +3 more
doaj +1 more source