Results 91 to 100 of about 164,160 (174)

The Trypanosoma brucei sphingolipid synthase, an essential enzyme and a drug target [PDF]

, 2009
Sphingolipids are important structural components of eukaryotic membranes, in addition they and their precursors are involved in signal transduction processes.
Pan, Ssu-Ying
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Effects of NO synthase inhibitors on the synovial microcirculation in the mouse knee joint [PDF]

, 1999
Production of nitric oxide by the inducible NO synthase (iNOS) is known to be enhanced in chronic joint inflammation and osteoarthritis as well as aseptic loosening of joint prostheses.
Refior, H. J., Messmer, K., Krombach, F., Veihelmann, A.   +3 more
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Systematically Analyzing the Pathogenic Variations for Acute Intermittent Porphyria

Frontiers in Pharmacology, 2019
The rare autosomal dominant disorder acute intermittent porphyria (AIP) is caused by the deficient activity of hydroxymethylbilane synthase (HMBS).
Yibao Fu, Jinmeng Jia, Lishu Yue, Ruiying Yang, Yongli Guo, Yongli Guo, Yongli Guo, Xin Ni, Xin Ni, Xin Ni, Tieliu Shi, Tieliu Shi   +11 more
doaj   +1 more source

The importance of sucrose synthase for AM symbiosis in maize, in pea and in Medicago [PDF]

, 2002
The arbuscular mycorrhiza (AM) is probably the most widespread symbiotic associations on earth, occurring in the roots of about 90 % of the land plant species. The fungal partners are soil-borne fungi of the order Glomales in the phylum of Glomero.
Corbière, Hélène Louise Françoise
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First report of Babesia gibsoni in Central America and survey for vector-borne infections in dogs from Nicaragua

Parasites & Vectors, 2014
Background Although many vector-borne diseases are important causes of morbidity and mortality in dogs in tropical areas and potential zoonoses, there is little information on these conditions in Central America.
Lanjing Wei, Patrick Kelly, Kate Ackerson, Jilei Zhang, Heba S El-Mahallawy, Bernhard Kaltenboeck, Chengming Wang   +6 more
doaj   +1 more source

Structural-functional correlations of Hydroxymethylbilane synthase

, 2009
Acute intermittent porphyria (AIP) is an autosomal dominantly inherited disorder, classified as acute hepatic porphyria. It is characterized by a deficiency of hydroxymethylbilane synthase (HMBS, EC 4.3.1.8), the third enzyme in heme biosynthesis ...
Douděrová, Dana
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Lipopolysaccharide induces nitric oxide synthase expression and platelet-activating factor increases nitric oxide production in human fetal membranes in culture [PDF]

, 2004
Platelet-activating factor and nitric oxide may be involved in the initiation of human labour as inflammatory mediators. The aim of this study was to test whether platelet-activating factor and lipopolysaccharide were able to induce nitric oxide synthase
Damian J Murphy, Dunmore, Simon J., Murphy Damian J, Carson Ray J, Rodrigo, Nalinda, Seyffarth Gunter, Nelson, Paul N., Dunmore Simon J, Simon J Dunmore, Nalinda Rodrigo, Carson, Ray J., Seyffarth, Gunther, Rodrigo Nalinda, Paul N Nelson, Murphy, Damian J., Nelson Paul N, Gunter Seyffarth, Ray J Carson   +17 more
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Table1_Molecular analysis of eight splicing variants in the hydroxymethylbilane synthase gene.docx

, 2023
Background: Molecular genetic testing is the most sensitive and specific method to confirm acute intermittent porphyria (AIP), a rare autosomal dominant disease, caused by Hydroxymethylbilane synthase (HMBS) gene mutation.
Shuang Li (146392), Fei Gao (29262), Jiajia Wang (157207), Jianhong Wang (225432), Yi Ren (30049), Jiajia Lei (13966887), Jianhong Yin (17415276), Yan Wang (15435), Jing Yang (13969), Yunfeng Liu (477558)   +9 more
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Whole Exome Sequencing Identified a Novel Heterozygous Mutation in HMBS Gene in a Chinese Patient With Acute Intermittent Porphyria With Rare Type of Mild Anemia

Frontiers in Genetics, 2018
Acute intermittent porphyria (AIP) is a rare hereditary metabolic disease with an autosomal dominant mode of inheritance. Germline mutations of HMBS gene causes AIP.
Yongjiang Zheng, Jiehua Xu, Shengran Liang, Dongjun Lin, Santasree Banerjee   +4 more
doaj   +1 more source

Acute Intermittent Porphyria: Diagnostic Conundrums [PDF]

, 1994
Summary: Acute intermittent porphyria is a genetic disorder of haem biosynthesis caused by defects in the gene encoding hydroxymethylbilane synthase on the long arm of chromosome 11.
T. J. Peters, W. S. Wassif, Thunell, S., Ylva Flodenis, A. C. Deacon, Peters, T. J., Floderus, Ylva, Wassif, W. S., Deacon, A. C., S. Tliunelp   +9 more
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