Results 121 to 130 of about 3,705 (210)

Detection of specific HPV subtypes responsible for the pathogenesis of condylomata acuminata. [PDF]

, 2013
BACKGROUND: The low-risk human papillomavirus types 6 and 11 are responsible for approximately 90% of anogenital wart cases, with approximately 190,000 new and recurrent cases reported in the UK in 2010.
Ball, Siolian LR, Goon, Peter KC, Hawkins, Matthew G, Sonnex, Christopher, Stanley, Margaret A, Sterling, Jane C, Vaughan, Katie, Winder, David M   +7 more
core   +4 more sources

Identification and characterization of 40 novel hydroxymethylbilane synthase mutations that cause acute intermittent porphyria [PDF]

, 2018
Brenden Chen, Constanza Solis‐Villa, Angelika Erwin, Manisha Balwani, Irina Nazrenko, John D. Phillips, Robert J. Desnick, Makiko Yasuda   +7 more
openalex   +1 more source

Structural evidence for the partially oxidized dipyrromethene and dipyrromethanone forms of the cofactor of porphobilinogen deaminase: structures of the Bacillus megaterium enzyme at near-atomic resolution. [PDF]

, 2014
The enzyme porphobilinogen deaminase (PBGD; hydroxymethylbilane synthase; EC 2.5.1.61) catalyses an early step of the tetrapyrrole-biosynthesis pathway in which four molecules of the monopyrrole porphobilinogen are condensed to form a linear tetrapyrrole.
Akhtar, M, Azim, N, Coker, A, Cooper, JB, Deery, E, Erskine, P, Warren, MJ, Wolfenden, BA, Wood, SP   +8 more
core   +1 more source

Decision letter for "Identification and molecular analysis of 17 novel variants of hydroxymethylbilane synthase in Chinese patients with acute intermittent porphyria"

, 2021

openalex   +2 more sources

Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis [PDF]

, 2008
Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute.
Anura Hewagama, Bruce C. Richardson, Dipak Patel, Faith M. Strickland, Sushma Yarlagadda   +4 more
core   +1 more source

A method to correlate mRNA expression datasets obtained from fresh frozen and formalin-fixed, paraffin-embedded tissue samples: A matter of thresholds [PDF]

, 2015
Background: Gene expression profiling of tumors is a successful tool for the discovery of new cancer biomarkers and potential targets for the development of new therapeutic strategies.
Foekens, J.A. (John), Kros, J.M. (Johan), Martens, J.W.M. (John W. M.), Meijer van Gelder, M.E. (Marion), Mustafa, D.A.M. (Dana), Sieuwerts, A.M. (Anieta), Smid, M. (Marcel), Weerd, V. (Vanja) de, Weiden, M.M. (Marcel) van der   +8 more
core   +1 more source

Peroxisome proliferator-activated receptor γ agonism attenuates endotoxaemia-induced muscle protein loss and lactate accumulation in rats [PDF]

, 2017
The peroxisome proliferator-activated receptor γ (PPARγ) agonist rosiglitazone (Rosi) appears to provide protection against organ dysfunction during endotoxaemia.
Alamdari, Berger, Bergmeyer, Bodine, Cai, Chew, Collin, Crossland, Crossland, Dawson, Dumitru Constantin-Teodosiu, Ebisui, Forsberg, Furuyama, Gamrin, Garcia-Martinez, Hannah Crossland, Harris, Kim, Klaude, Lang, Lecker, Lecker, Lee, Lehmann, Li, Liu, Lowry, Mallinson, Mammucari, Milan, Murch, Murton, Paul L. Greenhaff, Plomgaard, Ricote, Sandri, Sheila M. Gardiner, Smith, Soop, Stitt, Tawa, Vary, Voisin, Wang, Wieland, Wray, Yamazaki, Zhao, Zhou   +49 more
core   +2 more sources

Critical evaluation of HPV16 gene copy number quantification by SYBR green PCR

BMC Biotechnology, 2008
Background Human papilloma virus (HPV) load and physical status are considered useful parameters for clinical evaluation of cervical squamous cell neoplasia. However, the errors implicit in HPV gene quantification by PCR are not well documented.
Pett Mark R, Herdman Michael T, Stanley Margaret, Foster Nicola, Ng Grace, Roberts Ian, Teschendorff Andrew, Coleman Nicholas   +7 more
doaj   +1 more source

Acute intermittent porphyria caused by novel mutation in HMBS gene, misdiagnosed as cholecystitis

Neuropsychiatric Disease and Treatment, 2014
Majid Alfadhel,1,3 Neam Saleh,2 Helal Alenazi,2 Henry Baffoe-Bonnie21Division of Genetics, Department of Pediatrics, 2Division of General Medicine, Department of Medicine, King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia; 3College of Medicine,
Alfadhel M, Saleh N, Alenazi H, Baffoe-Bonnie H   +3 more
doaj  

Trends and Challenges in Experimental Macromolecular Crystallography [PDF]

, 2017
Macromolecular X-ray crystallography underpins the vigorous field of structural molecular biology having yielded many protein, nucleic acid and virus structures in fine detail.
Boggon, T. J., Cassetta, A., Chayen, N. E., Deacon, A., Gleichmann, T., Habash, J., Harrop, S. J., Helliwell, J. R., Hädener, A., Nieh, Y. P., Niemann, A. C., Peterson, M. R., Raftery, J., Siddons, D. P., Snell, E. H., Stojanoff, V., Thompson, A. W., Ursby, T., Wulff, M.   +18 more
core