Hydroxymethylglutaryl-coa reductase inhibitors

Results 121 to 130 of about 13,094 (219)

A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters.

The Journal of biological chemistry, 2000
A novel human organic transporter, OATP2, has been identified that transports taurocholic acid, the adrenal androgen dehydroepiandrosterone sulfate, and thyroid hormone, as well as the hydroxymethylglutaryl-CoA reductase inhibitor, pravastatin. OATP2 is expressed exclusively in liver in contrast to all other known transporter subtypes that are found in
B, Hsiang +6 more
openaire +1 more source

Statins decrease mortality in Lebanese patients with sepsis: A multicenter study

Pharmacy Practice, 2013
Background: Sepsis is a significant public health concern. The clinical response to statins is variable among sepsis patients. Objective: The aim of the study was to determinate the effect of statin-treatment on mortality in Lebanese patients with sepsis.
Ajrouche R +6 more
doaj

The discovery of PCSK9 inhibitors: A tale of creativity and multifaceted translational research. [PDF]

, 2013
Elguindy, A, Yacoub, MH
core +1 more source

Switching to rosuvastatin plus ezetimibe in statin-treated stroke patients with low-density lipoprotein cholesterol levels above 70 mg/dL (SWITCH): a prospective observational study

Lipids in Health and Disease
Background Effective lipid management is critical for secondary stroke prevention, however, many patients fail to achieve target low-density lipoprotein cholesterol (LDL-C) levels with statin monotherapy. This study evaluated the real-world effectiveness
Wookjin Yang +18 more
doaj +1 more source

Evaluating early administration of the hydroxymethylglutaryl-CoA reductase inhibitor simvastatin in the prevention and treatment of delirium in critically ill ventilated patients: a randomised, placebo-controlled trial (MoDUS)

, 2017
Background: Delirium in critically ill patients is associated with poor clinical outcomes. Neuroinflammation might be an important mechanism in the pathogenesis of delirium, and since simvastatin has anti-inflammatory properties it might reduce delirium.
Page, Valerie J. +6 more
openaire +2 more sources

Statins for the treatment of dementia [PDF]