Results 111 to 120 of about 764,872 (173)

Estudo do Inibidor da 3-Hidróxi-3-Metilglutaril- Coenzima A Redutase (Atorvastatina) na Transmissão e Toxicidade Glutamatérgica [PDF]

open access: yes, 2008
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.O glutamato é o principal neurotransmissor excitatório no Sistema Nervoso Central (SNC) de mamíferos participando da comunicação celular e diversas outras ...
Stroeh, Ellen
core  

The role of Coenzyme Q10 in statin-associated myopathy [PDF]

open access: yes, 2009
Statins, or 3-hydroxyl-3-methylglutaryl coenzyme HMG-CoA reductase inhibitors,\ud are cholesterol-lowering drugs which are frequently used in the primary and secondary\ud prevention of coronary artery disease. Current research and recommendations support\
Kalra, Dr Sanjay
core  

Effects of compactin, mevalonate and low-density lipoprotein on 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and low-density-lipoprotein-receptor activity in the human hepatoma cell line Hep G2

open access: yes, 1984
Compactin, an inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl-CoA) reductase, decreased cholesterol synthesis in intact Hep G2 cells. However, after the inhibitor was washed away, the HMG-CoA-reductase activity determined in the cell homogenate was ...
Griffioen, M., Havekes, L., Cohen, L.H.
core  

Exploration of natural product ingredients as inhibitors of human HMG-CoA reductase through structure-based virtual screening

open access: yes, 2015
Shih-Hung Lin,1 Kao-Jean Huang,1,2 Ching-Feng Weng,1 David Shiuan1 1Department of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien, Taiwan, Republic of China; 2Development Center of Biotechnology, Taipei, Taiwan ...
Huang KJ, Shiuan D, Weng CF, Lin SH
core  

Effects of HMG-CoA Reductase Inhibitors (Statins) On Bone Mineral Density and Metabolism

open access: yes, 2004
Hydroxy methylglutaryl coenzyme A reductase inhibitors (statins) have been shown to have effects on bone metabolism in laboratory studies. While early clinic studies have showed lower risk for osteoporotic fractures among statin users than nonusers ...
Mehmet Arman   +3 more
core  

HMG-CoA reductase inhibitors: Effects on chronic subacute inflammaton and onset of athesosclerosis induced by dietary cholesterol

open access: yes, 2005
Besides classical risk factors such as hypercholesterolemia and hypertension, chronic subacute inflammation has recently been recognized as an important force driving the development of atherosclerosis, the most common underlying cause of myocardial ...
Kooistra, T., Kleemann, R.
core  

Atorvastatin-Associated Liver Injury: Outcome After Statin Rechallenge. [PDF]

open access: yesFundam Clin Pharmacol
Bertin B   +5 more
europepmc   +1 more source

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