Results 121 to 130 of about 13,154 (208)

Evaluating early administration of the hydroxymethylglutaryl-CoA reductase inhibitor simvastatin in the prevention and treatment of delirium in critically ill ventilated patients: a randomised, placebo-controlled trial (MoDUS)

, 2017
Background: Delirium in critically ill patients is associated with poor clinical outcomes. Neuroinflammation might be an important mechanism in the pathogenesis of delirium, and since simvastatin has anti-inflammatory properties it might reduce delirium.
Page, Valerie J., Casarin, Annalisa, Ely, E. Wesley, Zhao, Xiaobei Bei, McDowell, Cliona, Murphy, Lynn, McAuley, Danny F   +6 more
openaire   +2 more sources

The discovery of PCSK9 inhibitors: A tale of creativity and multifaceted translational research. [PDF]

, 2013
Elguindy, A, Yacoub, MH
core   +1 more source

Drug interaction potential of 2-((3,4-dichlorophenethyl)(propyl)amino)-1-(pyridin-3-yl)ethanol (LK-935), the novel nonstatin-type cholesterol-lowering agent [PDF]

, 2014
Acimovic J, Bernhardt R, Kocjan D, Kuzman D, Kóbori László, Kőhalmy Krisztina, Monostory Katalin, Pascussi JM, Rozman D, Szabó Pál Tamás, Temesvári Manna, Wilzewski B   +11 more
core   +1 more source

Lipid-Lowering Efficacy and Adverse Events of CETP Inhibitor Combination Therapy: A Systematic Review and Network Meta-Analysis. [PDF]

J Cardiovasc Pharmacol
Guo P, Yu X, Wei X, Xiong X, Jiang J.
europepmc   +1 more source

Computational Evaluation of Statin Analogs Targeting HMG-CoA Reductase for Coronary Artery Disease Treatment. [PDF]

ChemistryOpen
Mtulo YB, Deogratias G, Mgaya JE, Paluch AS, Paul L.   +4 more
europepmc   +1 more source

Natural products as HMG-CoA reductase inhibitors (statins) for the management of non-communicable diseases. [PDF]

Inflammopharmacology
Muhammad RN, Aborehab NM, Aly SH, Nasr NN, Hindam MO, Mustafa AM, Faheem SA, Fawzy MH, Abo-El Fetoh ME, El-Dessouki AM, Rabie MA, El-Shiekh RA, Youssef ME.   +12 more
europepmc   +1 more source

Intracellular cholesterol transport proteins: roles in health and disease [PDF]

, 2016
Graham, Annette, Soffientini, Ugo
core   +1 more source

Current perspectives on lipid management in diabetic kidney disease: Can fibrates offer advantages over statins for renal outcomes? [PDF]

J Res Med Sci
Chitsazi MR, Safari F, Malekpour E, Mirzaei SA, Shafieyoun MH, Golafshan F, Rouzbahani H, Nekookhoo M, Noursina A, Siavash M.   +9 more
europepmc   +1 more source

Lipid metabolism in colorectal cancer: dual roles and statin therapy. [PDF]

Discov Oncol
Lu P, Wang Z.
europepmc   +1 more source

Clinical efficacy of combining fenofibrate with statins in patients with diabetes and hyperlipidemia: a meta-analysis. [PDF]

Front Endocrinol (Lausanne)
Huang J, Meng K, Qiu H.
europepmc   +1 more source