Results 1 to 10 of about 27,341 (230)
Effect of Ezetimibe on Glucose Metabolism and Inflammatory Markers in Adipose Tissue
Biomedicines, 2020 Despite numerous studies, the effects of ezetimibe on glucose metabolism are poorly understood. Here, we aimed to investigate the effects of ezetimibe on glucose metabolism and the expression of inflammatory markers.
Yongin Cho +2 more
exaly +4 more sources
Ezetimibe and Cancer: Is There a Connection?
Frontiers in Pharmacology, 2022 The high level of serum cholesterol caused by the excessive absorption of cholesterol can lead to hypercholesteremia, thus promoting the occurrence and development of cancer.
Jia Gu +8 more
doaj +2 more sources
Expanding the therapeutic landscape: ezetimibe as non-statin therapy for dyslipidemia [PDF]
The Korean Journal of Internal Medicine, 2023 Dyslipidemia is a significant risk factor for atherosclerotic cardiovascular disease (ASCVD), and statins are the primary therapeutic options for reducing low-density lipoprotein cholesterol (LDL-C) levels.
Jeongmin Lee, Seung-Hwan Lee
doaj +2 more sources
Bioscience Journal, 2023 Ezetimibe is an approved drug for lowering plasma LDL (low-density lipoprotein) level via inhibition of cholesterol absorption. Derivatives of ezetimibe reduce inflammatory response and oxidative stress.
Suhyeon Park, Ji-Soo Park, Sang-Kyu Park
doaj +3 more sources
Frontiers in Immunology, 2022 Ankylosing spondylitis (AS) is a chronic inflammatory disease that causes spinal inflammation and fusion. Although the cause of AS is unknown, genetic factors (e.g., HLA-B27) and environmental factors (e.g., sex, age, and infection) increase the risk of ...
Jeonghyeon Moon +18 more
doaj +2 more sources
Trends in Ezetimibe Prescriptions as Monotherapy or Fixed-Dose Combination in Germany 2012–2021
Frontiers in Cardiovascular Medicine, 2022 AimsAddition of ezetimibe to statin therapy is recommended by current guidelines when low-density lipoprotein cholesterol (LDL-C) targets are not achieved with statin monotherapy.
Julius L. Katzmann +7 more
doaj +2 more sources
Journal of Lipid Research, 2009 This study evaluates changes in cholesterol balance in hypercholesterolemic subjects following treatment with an inhibitor of cholesterol absorption or cholesterol synthesis or coadministration of both agents. This was a randomized, double blind, placebo-
Thomas Sudhop +2 more
exaly +3 more sources
Pharmaceutics, 2022 Two active pharmaceutical ingredients (APIs) with limited solubility, simvastatin and ezetimibe, prepared as a drug-drug solid dispersion (SD) was evaluated for physicochemical, microstructural, and aqueous dissolution properties.
Agata Górniak +4 more
doaj +2 more sources
Ezetimibe alone for over 75 years old as a primary prevention to decrease cardiovascular events [PDF]
Annals of MedicineThe EWTOPIA 75 (Ezetimibe Lipid-Lowering Trial on Prevention of Atherosclerotic Cardiovascular Disease in 75 or Older) study supports the reduction in the risk of atherosclerotic cardiovascular disease (ASCVD) events with ezetimibe without statin therapy
Alpo Vuorio +2 more
doaj +2 more sources
Разработка и регистрация лекарственных средств, 2023 Introduction. As a part of the registration of the drug product a bioequivalence study of the fixed-dose combination "Ezetimibe + rosuvastatin" (JSC "Sanofi-aventis group", Russia) compared with coadministered Ezetrol® (ezetimibe) and Crestor ...
A. L. Khokhlov +6 more
doaj +1 more source