Results 101 to 110 of about 31,786 (211)
Advanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. ABSTRACT Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen +9 more
wiley +1 more source
RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy
Advanced Science, Volume 13, Issue 13, 3 March 2026.This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu +12 more
wiley +1 more source
Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription
Advanced Science, Volume 13, Issue 13, 3 March 2026.This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen +14 more
wiley +1 more source
Advanced Science, Volume 13, Issue 13, 3 March 2026.Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan +19 more
wiley +1 more source
Медицинский вестник Юга России, 2012 Purpose: To evaluate the prevalence and the role of undifferentiated connective tissue dysplasia in the pathogenesis of recurrent erysipelas.Materials and Methods: This retrospective study includes patients with primary and recurrent erysipelas who ...
A. B. Ashirova, S. N. Orlova
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Food Frontiers, Volume 7, Issue 2, March 2026.Hesperetin inhibits bleomycin‐induced idiopathic pulmonary fibrosis by regulating gut microbiota and acetate and butyrate levels via the gut‐lung axis. ABSTRACT In the post‐epidemic and aging era, idiopathic pulmonary fibrosis (IPF) has become one of the major diseases endangering human health.
Xia Meng +9 more
wiley +1 more source
Food Frontiers, Volume 7, Issue 2, March 2026.Anti‐photoaging effects of Ganoderma lucidum‐derived ergothioneine in UVB‐irradiated HaCaT cells and skin photoaging mice. ABSTRACT The increasing incidence of skin photoaging associated with enhanced ultraviolet (UV) exposure highlights the need for effective preventive and therapeutic interventions.
Zihao Zong +12 more
wiley +1 more source
Uncovering the role of genetic polymorphisms in cervical insufficiency
International Journal of Gynecology &Obstetrics, Volume 172, Issue 3, Page 1335-1341, March 2026.Pathways and genes implicated in CI pathogenesis. Abstract Cervical insufficiency (CI) is characterized by spontaneous dilation of the cervix in the absence of painful uterine contractions in the mid‐trimester, leading to premature delivery. It is responsible for up to 20% of second trimester pregnancy losses, mostly <24 weeks.
Kallirhoe Kalinderi +3 more
wiley +1 more source
Journal of Intelligent Medicine, Volume 3, Issue 1, Page 47-68, March 2026.Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran +5 more
wiley +1 more source