Results 61 to 70 of about 31,786 (211)
Journal of Education, Health and Sport, 2019 In the experiments on 27 old female rats, the effect of the anthracene derivative preparation on the state of the intercellular matrix of the connective tissue of the periodontal and oral mucosa in intact animals, as well as on the periodontitis model ...
N. N. Savelieva +3 more
doaj
Медицинский вестник Юга России, 2017 Objective: study and analyse features of metabolic disorders of connective tissue in postoperative abdominal hernia and its possible resolution.Materials and methods: 68 patients with postoperative ventral hernias of different age groups were studied and
S. G. Grivenko +2 more
doaj +1 more source
Move beyond free radical theory of aging
iMetaOmics, EarlyView.Free radicals play a dual, dose‐dependent role in aging. Low levels activate the key sensor adenosine 5'‐monophosphate‐activated protein kinase (AMPK), promoting cell survival mechanisms like autophagy and enhancing mitochondrial health. High levels, however, push AMPK to initiate cell death pathways, such as apoptosis. This positions AMPK as a central
Xiaofeng Dai, Meilan Hu, Ruohan Lyu
wiley +1 more source
Data‐Driven Engineering of Thermostable Collagen‐Mimetic Peptoid Triple Helices
Macromolecular Rapid Communications, EarlyView.Data‐driven active learning discovery of collagen‐mimetic peptoids capable of forming a thermostable collagen‐like triple helix using computational screening followed by experimental validation. ABSTRACT Collagen‐mimetic peptides (CMPs) are engineered molecules designed to replicate the triple‐helical structure of natural collagen.
Alex Berlaga +6 more
wiley +1 more source
PM&R, EarlyView.Abstract Background Osteoporosis fractures pose a significant public health concern, leading to substantial morbidity and mortality rates. The emerging evidence on the potential link between gut microbiota, proteins, and osteoporosis fractures suggests a complex relationship that warrants further investigation.
Qiong Wang +6 more
wiley +1 more source
Journal of Polymer Science, EarlyView.Gelatin derived from porcine tissue and sericin extracted from Bombyx mori cocoons are combined to form crosslinker‐free hydrogels with tunable composition, enabling extrusion‐based 3D printing and biocompatible constructs for biomedical applications. ABSTRACT Hydrogels can be processed by 3D printing to manufacture tailor made structures, broadening ...
André S. Macedo +7 more
wiley +1 more source
AlphaFold2‐Guided Cyclic Peptide Stabilizer Design to Target Protein–Protein Interactions
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The control and modulation of protein–protein interactions (PPIs) is of central importance for the majority of biological processes and most biomedical applications. Stabilization of PPIs, besides inhibition, is of growing pharmaceutical interest.
Niklas Halbwedl, Martin Zacharias
wiley +1 more source
Rapid Communications in Mass Spectrometry, EarlyView.ABSTRACT Rationale Recent advances in high‐throughput molecular analyses of collagen peptides, especially ZooMS (Zooarchaeology by Mass Spectrometry), have permitted breakthroughs in the analysis of archaeological material that is highly fragmented, a factor that hinders morphological identification.
Pauline Raymond +8 more
wiley +1 more source
Effects of Calcium Dobesilate on Colonic Anastomosis Healing: An Experimental Study
Turkish Journal of Colorectal Disease, 2019 Aim:Anastomotic leakage in colon anastomosis (CA) increases morbidity and mortality. Calcium dobesilate (CaD) has angioprotective, antioxidant, lymphatic flow enhancing-and neuroprotective effects.
Süleyman Demiryas +12 more
doaj +1 more source