Results 161 to 170 of about 30,831 (196)
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Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC)
Advanced Drug Delivery Reviews, 2001The objective of this article is to review the spectrum of mathematical models that have been developed to describe drug release from hydroxypropyl methylcellulose (HPMC)-based pharmaceutical devices. The major advantages of these models are: (i) the elucidation of the underlying mass transport mechanisms; and (ii) the possibility to predict the effect
Jürgen Siepmann, N A Peppas, N A Peppas
exaly +3 more sources
International Journal of Pharmaceutics, 2020
Controlled release tablets are important dosage forms enabling a slower release of the drug and better pharmacokinetics for some drugs and hydrophilic matrix tablets utilizing hydroxypropyl methylcellulose (HPMC) are one of the most common types. One of the main challenges with using HPMC is its poor flow when implemented in a direct compression ...
Tamara Minko +2 more
exaly +3 more sources
Controlled release tablets are important dosage forms enabling a slower release of the drug and better pharmacokinetics for some drugs and hydrophilic matrix tablets utilizing hydroxypropyl methylcellulose (HPMC) are one of the most common types. One of the main challenges with using HPMC is its poor flow when implemented in a direct compression ...
Tamara Minko +2 more
exaly +3 more sources
Stabilization of Misoprostol with Hydroxypropyl Methylcellulose (HPMC) Against Degradation by Water
Pharmaceutical Research, 1990The stability of misoprostol oil is significantly improved in a hydroxypropyl methylcellulose (HPMC) dispersion (1:100). In order to assess the effect of water on misoprostol stability, the rate of misoprostol degradation was investigated in the misoprostol/HPMC dispersion at 55 degrees C, along with the water sorption isotherm, under seven different ...
T T, Kararli, T, Catalano
exaly +3 more sources
Food and Chemical Toxicology, 2012
The effect of hydroxyethyl methylcellulose (HEMC), in comparison with hydroxypropyl methylcellulose (HPMC), on the body weight and lipid metabolism in mice fed with high fat diet was investigated. The animals were given normal control diet (NC group), high fat diet (HF group), or high fat diet supplemented with either HEMC (HF+HEMC group) or HPMC (HF ...
In Chul Um +2 more
exaly +3 more sources
The effect of hydroxyethyl methylcellulose (HEMC), in comparison with hydroxypropyl methylcellulose (HPMC), on the body weight and lipid metabolism in mice fed with high fat diet was investigated. The animals were given normal control diet (NC group), high fat diet (HF group), or high fat diet supplemented with either HEMC (HF+HEMC group) or HPMC (HF ...
In Chul Um +2 more
exaly +3 more sources
Calorimetric Studies of Dissolution of Hydroxypropyl Methylcellulose E5 (HPMC E5) in Water
Journal of Pharmaceutical Sciences, 1993The interaction of water with polymers is important because it directly or indirectly affects various properties such as rheological and transport properties. In this study, the hydration/dissolution of a hydrophilic polymer was investigated by calorimetric techniques.
H N, Joshi, T D, Wilson
openaire +2 more sources
International Journal of Pharmaceutics, 2020
An extrusion based 3D printer was used to prepare the semi-solid tablets with different drug loading dosages (75, 100, 125 mg) under ambient temperature. The active pharmaceutical ingredient, theophylline, was uploaded within the hydrogels prepared of hydroxypropyl methylcellulose (HPMC) K4M or E4M.
Yiliang Cheng +2 more
exaly +3 more sources
An extrusion based 3D printer was used to prepare the semi-solid tablets with different drug loading dosages (75, 100, 125 mg) under ambient temperature. The active pharmaceutical ingredient, theophylline, was uploaded within the hydrogels prepared of hydroxypropyl methylcellulose (HPMC) K4M or E4M.
Yiliang Cheng +2 more
exaly +3 more sources
Ophthalmic Plastic & Reconstructive Surgery, 2005
The insertion of an orbital implant in the posterior Tenon's space or in the eviscerated sclera must be smooth, without entrapment or dragging of adjacent soft tissue. Anterior Tenon's fascia and conjunctiva must be closed without undue tension that could lead to subsequent postoperative implant exposure.
D Julian, de Silva, Jane M, Olver
openaire +2 more sources
The insertion of an orbital implant in the posterior Tenon's space or in the eviscerated sclera must be smooth, without entrapment or dragging of adjacent soft tissue. Anterior Tenon's fascia and conjunctiva must be closed without undue tension that could lead to subsequent postoperative implant exposure.
D Julian, de Silva, Jane M, Olver
openaire +2 more sources
Carbohydrate Polymers, 2014
The influence of the physicochemical parameters of substituted aromatic molecules on the phase transition from sol to gel of hydroxypropyl methylcellulose (HPMC) has been investigated using a homologous series of substituted phenols. Using a turbimetric methodology, concentration dependent suppression of phase transition temperature of HPMC was ...
Simon R, Banks +5 more
openaire +2 more sources
The influence of the physicochemical parameters of substituted aromatic molecules on the phase transition from sol to gel of hydroxypropyl methylcellulose (HPMC) has been investigated using a homologous series of substituted phenols. Using a turbimetric methodology, concentration dependent suppression of phase transition temperature of HPMC was ...
Simon R, Banks +5 more
openaire +2 more sources
European Journal of Pharmaceutics and Biopharmaceutics, 2010
Scratch resistance (SR) of externally plasticized hydroxypropyl methylcellulose (HPMC) films intended for tablet film coatings was studied. Special attention was paid to effects of short-term aging and ultraviolet (UV) treatment on the SR properties of these films.
Hanhijärvi, Kalle +8 more
openaire +4 more sources
Scratch resistance (SR) of externally plasticized hydroxypropyl methylcellulose (HPMC) films intended for tablet film coatings was studied. Special attention was paid to effects of short-term aging and ultraviolet (UV) treatment on the SR properties of these films.
Hanhijärvi, Kalle +8 more
openaire +4 more sources
Pakistan journal of pharmaceutical sciences, 2022
Meloxicam (MEL) is an oxicam derivative with low water solubility that is useful in the treatment of colorectal cancer (CRC) as a COX-2 inhibitor. MEL-loaded HPMC micro particles were fabricated using an oil-in-oil (o/o) emulsion solvent evaporation (ESE) method.
Syed Abdul, Wasay +10 more
openaire +3 more sources
Meloxicam (MEL) is an oxicam derivative with low water solubility that is useful in the treatment of colorectal cancer (CRC) as a COX-2 inhibitor. MEL-loaded HPMC micro particles were fabricated using an oil-in-oil (o/o) emulsion solvent evaporation (ESE) method.
Syed Abdul, Wasay +10 more
openaire +3 more sources