Results 51 to 60 of about 14,689 (241)

Redox‐Mediated Aluminum–Air Fuel Cells With Suppressed Hydrogen Evolution for Durable Power Generation

open access: yesAdvanced Energy Materials, EarlyView.
The redox‐mediated aluminum–air fuel cell (RM‐AAFC) integrates a soluble redox mediator, 7,8‐dihydroxy‐2‐phenazine sulfonic acid (DHPS), to facilitate the oxidation of aluminum and inhibit hydrogen evolution reaction (HER) through competitive reactions between DHPS reduction and HER on the Al surface.
Yuxi Song   +10 more
wiley   +1 more source

Synthesis and cytotoxic studies of a new series quinolinoxymethylcoumarins [PDF]

open access: yes, 2013
4-Bromomethylcoumarins (1a-k) were reacted with 8-hydroxyquinolines (2a-b) to yield quinolinoxymethylcoumarins (3a-o). The structure of all the synthesized compounds were confirmed by spectral studies and screened for their anticancer activities against ...
Pandi, V.   +4 more
core  

Epigenomic Regulation of Androgen Receptor Signaling: Potential Role in Prostate Cancer Therapy. [PDF]

open access: yes, 2017
Androgen receptor (AR) signaling remains the major oncogenic pathway in prostate cancer (PCa). Androgen-deprivation therapy (ADT) is the principle treatment for locally advanced and metastatic disease.
Cucchiara, Vito   +5 more
core   +2 more sources

Evaluation of a Product Intended for Microbiological Control in Animal Production, and Its Combination With Halquinol

open access: yesAnimal Research and One Health, EarlyView.
Activo Liquid and Halquinol inhibit Salmonella and Escherichia coli in culture media. Activo Liquid exhibits bactericidal action, whereas HA is bacteriostatic, and their combination results in positive or indifferent interactions. This combination effectively inhibits E. coli throughout digestion simulation, thus reducing the required concentrations of
Alberto Gonçalves Evangelista   +6 more
wiley   +1 more source

Prevention of Travelers' Diarrhea by Nonantibiotic Drugs [PDF]

open access: yes, 2017
Travelers have resorted to a variety of drugs for prevention of diarrhea. No beneficial prophylactic effect has been confirmed for halogenated hydroxyquinolines, lactobacilli, antimotility drugs, ethacridine, and various other agents.
DuPont, Herbert L.   +2 more
core  

Genetic code expansion for chemosensing and chemical actuation of biological functions

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Genetic code expansion (GCE) broadens the chemical repertoire for precise control of protein function in biological systems. This review highlights GCE‐based sensing and actuating systems that operate through selective interactions between noncanonical amino acids and chemical triggers.
Jieun Bae, Dong‐Hyun Kim, Minseob Koh
wiley   +1 more source

Anticancer drugs based on metal complexes of 2-imine-8-hydroxyquinolines

open access: yesFrontiers in Chemical Biology
Cancer treatment remains a public health challenge, requiring, more than ever, the development of effective and selective therapeutic drugs. Metal complexes of 8-hydroxyquinoline (8HQ) have long been recognized to exhibit significant potential in this ...
Leonor Côrte-Real   +2 more
doaj   +1 more source

Organocatalytic Enantioselective Functionalization of Hydroxyquinolines through an aza-Friedel-Crafts Alkylation with Isatin-derived Ketimines [PDF]

open access: yes, 2018
A highly enantioselective addition o hydroxyquinolines to isatin-derived ketimines hasbeen realized using a quinine-derived thiourea organocatalyst. The reaction affords chiral 3-amino-2-oxindoles bearing a quinoline moiety with a quaternary stereocenter
Aleman   +63 more
core   +2 more sources

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

open access: yesBMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang   +7 more
wiley   +1 more source

Cellular analysis of the action of epigenetics drugs and probes [PDF]

open access: yes, 2017
Small molecule drugs and probes are important tools in drug discovery, pharmacology, and cell biology. This is of course also true for epigenetic inhibitors.
A. Ganesan   +12 more
core   +1 more source

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