Results 51 to 60 of about 14,689 (241)
The redox‐mediated aluminum–air fuel cell (RM‐AAFC) integrates a soluble redox mediator, 7,8‐dihydroxy‐2‐phenazine sulfonic acid (DHPS), to facilitate the oxidation of aluminum and inhibit hydrogen evolution reaction (HER) through competitive reactions between DHPS reduction and HER on the Al surface.
Yuxi Song +10 more
wiley +1 more source
Synthesis and cytotoxic studies of a new series quinolinoxymethylcoumarins [PDF]
4-Bromomethylcoumarins (1a-k) were reacted with 8-hydroxyquinolines (2a-b) to yield quinolinoxymethylcoumarins (3a-o). The structure of all the synthesized compounds were confirmed by spectral studies and screened for their anticancer activities against ...
Pandi, V. +4 more
core
Epigenomic Regulation of Androgen Receptor Signaling: Potential Role in Prostate Cancer Therapy. [PDF]
Androgen receptor (AR) signaling remains the major oncogenic pathway in prostate cancer (PCa). Androgen-deprivation therapy (ADT) is the principle treatment for locally advanced and metastatic disease.
Cucchiara, Vito +5 more
core +2 more sources
Activo Liquid and Halquinol inhibit Salmonella and Escherichia coli in culture media. Activo Liquid exhibits bactericidal action, whereas HA is bacteriostatic, and their combination results in positive or indifferent interactions. This combination effectively inhibits E. coli throughout digestion simulation, thus reducing the required concentrations of
Alberto Gonçalves Evangelista +6 more
wiley +1 more source
Prevention of Travelers' Diarrhea by Nonantibiotic Drugs [PDF]
Travelers have resorted to a variety of drugs for prevention of diarrhea. No beneficial prophylactic effect has been confirmed for halogenated hydroxyquinolines, lactobacilli, antimotility drugs, ethacridine, and various other agents.
DuPont, Herbert L. +2 more
core
Genetic code expansion for chemosensing and chemical actuation of biological functions
Genetic code expansion (GCE) broadens the chemical repertoire for precise control of protein function in biological systems. This review highlights GCE‐based sensing and actuating systems that operate through selective interactions between noncanonical amino acids and chemical triggers.
Jieun Bae, Dong‐Hyun Kim, Minseob Koh
wiley +1 more source
Anticancer drugs based on metal complexes of 2-imine-8-hydroxyquinolines
Cancer treatment remains a public health challenge, requiring, more than ever, the development of effective and selective therapeutic drugs. Metal complexes of 8-hydroxyquinoline (8HQ) have long been recognized to exhibit significant potential in this ...
Leonor Côrte-Real +2 more
doaj +1 more source
Organocatalytic Enantioselective Functionalization of Hydroxyquinolines through an aza-Friedel-Crafts Alkylation with Isatin-derived Ketimines [PDF]
A highly enantioselective addition o hydroxyquinolines to isatin-derived ketimines hasbeen realized using a quinine-derived thiourea organocatalyst. The reaction affords chiral 3-amino-2-oxindoles bearing a quinoline moiety with a quaternary stereocenter
Aleman +63 more
core +2 more sources
Enhanced strategies for cuproptosis‐like death in bacterial infection treatment
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang +7 more
wiley +1 more source
Cellular analysis of the action of epigenetics drugs and probes [PDF]
Small molecule drugs and probes are important tools in drug discovery, pharmacology, and cell biology. This is of course also true for epigenetic inhibitors.
A. Ganesan +12 more
core +1 more source

