Molecules, 2021 Despite the common use of salens and hydroxyquinolines as therapeutic and bioactive agents, their metal complexes are still under development. Here, we report the synthesis of novel mixed-ligand metal complexes (MSQ) comprising salen (S), derived from (2,
Badriah Saad Al-Farhan +7 more
doaj +1 more source
Validated stability indicating liquid chromatographic determination of ebastine in pharmaceuticals after pre column derivatization: Application to tablets and content uniformity testing [PDF]
, 2011 An accurate, simple, sensitive and selective reversed phase liquid chromatographic method has been developed for the determination of ebastine in its pharmaceutical preparations. The proposed method depends on the complexation ability of the studied drug
Fawzia Ibrahim +3 more
core +2 more sources
, 2014 Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust +15 more
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Anti-trypanosomal 8-hydroxyl naphthyridines are chelators of divalent transition metals [PDF]
, 2018 The lack of information regarding the mechanisms of action (MoA) or specific molecular targets of phenotypically active compounds can prove a barrier to their development as chemotherapeutic agents.
Fairlamb, Alan +10 more
core +2 more sources
High-throughput screening with the Eimeria tenella CDC2-related kinase2/cyclin complex EtCRK2/EtCYC3a [PDF]
, 2012 The poultry disease coccidiosis, caused by infection with Eimeria spp. apicomplexan parasites, is responsible for enormous economic losses to the global poultry industry.
Aziz +12 more
core +1 more source
8‐Hydroxyquinolines are bactericidal against Mycobacterium tuberculosis
Drug development research (Print), 2019 There is an urgent need for new treatments effective against Mycobacterium tuberculosis, the causative agent of tuberculosis. The 8‐hydroxyquinoline series is a privileged scaffold with anticancer, antifungal, and antibacterial activities. We conducted a
J. Odingo +11 more
semanticscholar +1 more source
Synthesis of 4-Alkoxy-8-hydroxyquinolines [PDF]
The Journal of Organic Chemistry, 2007 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Juha P, Heiskanen +5 more
openaire +2 more sources
In vitro selective growth-inhibitory effect of 8-hydroxyquinoline on Clostridium perfringens versus Bifidobacteria in a medium containing chicken ileal digesta [PDF]
, 2016 Clostridium perfringens-induced necrotic enteritis is generally controlled by antibiotics. However, because of increasing antibiotic resistance, other antibacterial agents are required, preferably ones that do not affect the beneficial intestinal ...
Hovorkova, Petra +3 more
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Preparation of 8-hydroxyquinoline wires by decomposition of tris(8-hydroxyquinoline) aluminium [PDF]
Journal of Experimental Nanoscience, 2012 We fabricated 8-hydroxyquinoline (HQ) wires by two methods, decomposition of tris(HQ) aluminium at low pressure in a tube furnace and heating of HQ powder at atmospheric pressure. Fabricated wires were crystalline, and exhibited the same optical properties (absorption and photoluminescence) as HQ powder.
Chan, WK +4 more
openaire +3 more sources
The synthesis of Waltherione F and analogues with modifications at the 2- and 3-positions as potential antitrypanosomal agents [PDF]
, 2019 Chagas disease also know as American Trypanosomiasis (AT) is a tropical parasitic disease endemic in South America, is caused by Trypanosoma cruzi which is transmitted by the blood‐sucking insect vectors called triatomine bugs.
Arroyo Aguilar +20 more
core +1 more source