Results 111 to 120 of about 4,710,511 (291)

Enhancement of Classifier Performance with Adam and RanAdam Hyper-Parameter Tuning for Lung Cancer Detection from Microarray Data—In Pursuit of Precision

Bioengineering
Microarray gene expression analysis is a powerful technique used in cancer classification and research to identify and understand gene expression patterns that can differentiate between different cancer types, subtypes, and stages.
Karthika M S, Harikumar Rajaguru, Ajin R. Nair   +2 more
doaj   +1 more source

Hyper-parameter grid search predictive validity.

, 2018
Predictive validity metrics for the mean and standard deviation of attainment predictions of space-time distance model, over the grid of hyper-parameters tested using out-of-sample predictive validity.
Nicholas Graetz (5626766), Emmanuela Gakidou (250582), Joseph Friedman (6029804)   +2 more
core   +1 more source

Adaptive Network Stabilization Despite Profound Structural Reorganization in Human Organotypic Cultures

Advanced Science, EarlyView.
Adult human organotypic cortical slices undergo marked neuronal loss, laminar disruption, and glial activation, yet their network activity progressively stabilizes after a variable period. Electrophysiology, longitudinal calcium imaging, and quantitative histology show that structurally remodeled human circuits show adaptive capacity resulting in ...
Estilla Zsófia Tóth, Rebeka Stelcz, Réka Bod, Ábel Petik, Eszter Juhász, Kinga Tóth, Liza Szalai, Nour Essam, Fanni Somogyi, Beatrix Kovács, Amirmahdi Mojtahedzadeh, Attila György Bagó, Loránd Erőss, Péter Orbay, Johanna Petra Szabó, Dániel Fabó, Boglárka Hajnal, Bence Rácz, Daniel Hillier, István Ulbert, Lucia Wittner   +20 more
wiley   +1 more source

Hyper-parameters used in building empirical distributions.

, 2019
Hyper-parameters used in building empirical distributions.
Takayuki Kanda (295659), Adrien Gregorj (7512317), Claudio Feliciani (6103127), Francesco Zanlungo (295657), Zeynep Yucel (7512314)   +4 more
core   +1 more source

Developing Highly Effective Nanoparticle mRNA Therapeutic for Pediatric Acute Respiratory Distress Syndrome

Advanced Science, EarlyView.
Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng, Wen Gao, Jonathan Do, Danli Lu, Ying‐Wei Lan, Andreas Damianos, Gautam Verma, Ali Al Siraj, Isabella Lowry, Lance Peter, Nicholas E. Banovich, Fei Sun, Hua He, Tanya V. Kalin, Vladimir V. Kalinichenko   +14 more
wiley   +1 more source

Demonstration of hyper-programming in Java [PDF]

, 2011
We demonstrate the use of a hyper-programming system to build persistent Java applications in PJama, an orthogonally persistent version of Java. This allows program representations to contain type-safe links to persistent objects embedded directly within
Zirintsis, E, Morrison, Ronald, Kirby, Graham Njal Cameron   +2 more
core   +2 more sources

Plant Metabolites Screening Identifies 7‐epi‐10‐Deacetyltaxol Inhibiting Cell Division by Interfering With the Cell Cycle and Microtubule Organization

Advanced Science, EarlyView.
In this study, an efficient screening system is developed for plant metabolites to find a compound, 7‐epi‐10‐deacetyltaxol, inhibits tissue elongation. It suppresses plant growth through brassinosteroid and microtubule pathways. It is later applied to animal cells and human tumor organoids, resulting in similar cell division suppression. These findings
Yan‐Jie Zhang, Yu‐Xuan Bai, Geng G. Tian, Bin Zhang, Ding‐Yi Lu, Qing‐Ping Yao, Wen‐Hao Tian, Xiao‐Na Wei, Jing‐Ting Yang, Ze‐Yu Xiong, Yi Lu, Yu‐Tong Jiang, Chun‐Hui Cai, Yu‐Ming Lu, Xian‐Qing Jia, Li‐Li Jing, Bao‐Jun Yang, Ying‐Xin Qi, Xin‐Xin Han, Ji Wu, Wen‐Hui Lin   +20 more
wiley   +1 more source

NeuHH: A Neuromorphic-Inspired Hyper-Heuristic Framework for Solving the Capacitated Single-Allocation p-Hub Location Routing Problem

Vehicles
This paper introduces a novel neuromorphic-inspired hyper-heuristic framework (NeuHH) for solving the Capacitated Single-Allocation p-Hub Location Routing Problem (CSAp-HLRP), a challenging combinatorial optimization problem that jointly addresses hub ...
Kassem Danach, Hassan Harb, Semaan Amine, Mariem Belhor   +3 more
doaj   +1 more source

A Hepatocyte‐to‐Stellate Cell Axis Couples Alternate‐Day Fasting to Liver Fibrosis Resolution via ATG7 S‐Nitrosylation

Advanced Science, EarlyView.
Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang, Mengqi Zeng, Cunxiao Sun, Yuhan Gou, Zhaode Feng, Weiqiang Lv, Chaoying Yan, Hansen Wu, Pengfei Zhang, Jie Xu, Ke Cao, Hao Li, Mingge Ding, Zhongbo Liu, Xing Zhang, Jiankang Liu, Xuan Zou, Zhihui Feng   +17 more
wiley   +1 more source

Physics-informed two-tier neural network for non-linear model order reduction

Advanced Modeling and Simulation in Engineering Sciences
In recent years, machine learning (ML) has had a great impact in the area of non-intrusive, non-linear model order reduction (MOR). However, the offline training phase often still entails high computational costs since it requires numerous, expensive ...
Yankun Hong, Harshit Bansal, Karen Veroy
doaj   +1 more source