Results 91 to 100 of about 456,784 (284)

Contrasting Effects of Oxytocin on MK801-Induced Social and Non-Social Behavior Impairment and Hyperactivity in a Genetic Rat Model of Schizophrenia-Linked Features

Brain Sciences
Social withdrawal in rodents is a measure of asociality, an important negative symptom of schizophrenia. The Roman high- (RHA) and low-avoidance (RLA) rat strains have been reported to exhibit differential profiles in schizophrenia-relevant behavioral ...
Daniel Sampedro-Viana, Toni Cañete, Paula Ancil-Gascón, Sonia Cisci, Adolf Tobeña, Alberto Fernández-Teruel   +5 more
doaj   +1 more source

The effects of cyber bullying or victimization behaviors on social reciprocity and online cognition of adolescents with attention-deficit/hyperactivity disorder

Psychiatry and Behavioral Sciences, 2020
Objective: Cyberbullying or its victimization reported previously at a higher rate within adolescents with attention-deficit/hyperactivity disorder (ADHD) might have related with their social reciprocity or online cognition deficits.
Rezzan Aydin Gorucu, Cihat Kagan Gurkan, Merve Canli, Hilal Tugba Kilic   +3 more
doaj   +1 more source

ADHD : from childhood into adulthood [PDF]

, 2013
This is an overview of the some of the most recent and seminal research done on Attention Deficit Hyperactivity Disorders (ADHD). ADHD is currently one of the most common reasons for referral to child mental health services and still is under-recognised ...
Camilleri, Nigel, Makhoul, Samer
core  

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

Advanced Science, EarlyView.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang, Yuchen Wang, Binbin Li, Xin Li, Chenyu Liu, Yanhao Chen, Cheng Tian, Dongmei Wang, Xiaosong Gu, Chunping Jiang, Yuda Wei, Qiurong Ding   +11 more
wiley   +1 more source

Declaración de Cartagena para el Trastorno por Déficit de Atención con Hiperactividad (TDAH): rompiendo el estigma

Revista Ciencias de la Salud, 2010
In 2007, the Declaration of Mexico for Attention Deficit Hyperactivivity Disorder (ADHD) was developed by a group of specialists in mental health and neuroscience. This statement summarizes the most recent scientific information about the disorder.
Eduardo Barragán Pérez, Juan David Palacio Ortiz, Francisco De la Peña Olvera   +2 more
doaj  

Contribuição dos fatores de risco psicossociais para o transtorno de déficit de atenção/hiperatividade Contribution of psychosocial risk factors for attention deficit/hyperactivity disorder

Arquivos de Neuro-Psiquiatria, 2005
OBJETIVO: Analisar a contribuição dos fatores psicossociais para a ocorrência do transtorno de déficit de atenção/hiperatividade (TDAH). MÉTODO: Este é um estudo retrospectivo de casos-controles que analisou 403 alunos de uma escola pública primária ...
Marcio M. Vasconcelos, Ana Flávia de A. Malheiros, Jairo Werner Jr., Adriana R. Brito, Jane Bardawil Barbosa, Ítalo S. Oliveira Santos, Daniel Fampa N. Lima   +6 more
doaj   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

Locomotor hyperactivity in 14-3-3Zeta KO mice is associated with dopamine transporter dysfunction [PDF]

, 2013
Dopamine (DA) neurotransmission requires a complex series of enzymatic reactions that are tightly linked to catecholamine exocytosis and receptor interactions on pre- and postsynaptic neurons.
A Abi-Dargham, A Aitken, A Breier, A Vina-Vilaseca, AA Williams, AH Wong, B Giros, B Giros, BL Summers, BT Baune, C Itagaki, CA Tamminga, D Berg, D Sulzer, DL Levy, FA Middleton, H Fu, H Jaaro-Peled, H Khoshbouei, H Koike, HC Baxter, J Sun, J Wang, JA English, JA English, JA Lieberman, JA Lieberman, JH Son, JM van Rossum, K Toska, K Toyo-oka, K Toyo-Oka, KL Holton, M Laruelle, M Laruelle, M Miranda, M Rosner, M van den Buuse, M van den Buuse, MS Samuel, O Halskau Jr., P Coyle, PC Hart, PS Cheah, S Leucht, S Sivagnanasundaram, S Sivagnanasundaram, SG Amara, SR Jones, T Ichimura, T Ichimura, WC Drevets, WT Carpenter, Y Jia   +53 more
core   +2 more sources

ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC‐I Antigen Presentation That Promotes Tumor Immune Evasion

Advanced Science, EarlyView.
ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao, Linlin Sheng, Jianhao Qiu, Junjie Ma, Kai Jin, Binggong Zhao, Tianrun Miao, Jing Chen, Yehong Li, Zhan Zhang, Dongfeng Sun, Yongmeng Li, Hui Tian   +12 more
wiley   +1 more source

ADHD-associated risk taking is linked to exaggerated views of the benefits of positive outcomes [PDF]

, 2016
Attention deficit and hyperactivity disorder (ADHD) is often assumed to be associated with increased engagement in risk-taking behaviors. The current study sought to understand the mental processes underlying this association using a theory-driven ...
Aloni, Hamutal, Barke, Edmund, Pollak, Yehuda, Shoham, Rachel, Yaniv, Ilan   +4 more
core   +2 more sources