Results 21 to 30 of about 219,244 (264)

Association between Internet Gaming Disorder and Adult Attention Deficit and Hyperactivity Disorder among A Sample of Medical Students of Al-Azhar University, Damietta [PDF]

International Journal of Medical Arts, 2023
Background: When it interferes with their ability to perform in social, professional, familial, educational, and psychological ways, gaming can become pathological for some players.
Abdelmonem Ibrahim Ali, Abdullah Ahmed Mekky, Ayman Abdelmaksoud   +2 more
doaj   +1 more source

Gabapentin in Refractory Partial Seizures

Pediatric Neurology Briefs, 1996
The efficacy of gabapentin as an additional medication in 32 children with refractory partial seizures was studied at the Children’s Hospital, Boston, MA.
J Gordon Millichap
doaj   +1 more source

Disordered eating in anorexia nervosa: give me heat, not just food

Frontiers in Public Health
The recommendation to apply external heat to patients with anorexia nervosa (AN) was first documented by William Gull in 1874. Gull encountered this practice during his tenure as a consultant physician, responsible for issuing medical certifications for ...
Emilio Gutierrez, Emilio Gutierrez, Naomi García, Olaia Carrera, Olaia Carrera   +4 more
doaj   +1 more source

Hypothyroidism, Motor Clumsiness, and ADHD

Pediatric Neurology Briefs, 2001
The behavioral characteristics of 63 children with early-treated congenital hypothyroidism (CH) were evaluated by parent and teacher ratings and compared to 34 healthy controls (ages 7.5-9.5 yrs) at the University of Jyvaskyla, Finland.
J Gordon Millichap
doaj   +1 more source

Kluver-Bucy Syndrome after Meningoencephalitis

Pediatric Neurology Briefs, 2011
Researchers at Medical College of Georgia, Augusta, GA, report a 10-year-old girl with a history of Listeria monocytogenes meningoencephalitis, contracted at 2½ years of age, who developed behavioral changes consistent with Kluver-Bucy syndrome at 2 ...
J Gordon Millichap
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Associations of Hyperactivity and Inattention Scores with Theta and Beta Oscillatory Dynamics of EEG in Stop-Signal Task in Healthy Children 7–10 Years Old

Biology, 2021
In the current study, we aimed to investigate the associations between the natural variability in hyperactivity and inattention scores, as well as their combination with EEG oscillatory responses in the Stop-Signal task in a sample of healthy children ...
Andrey V. Bocharov, Alexander N. Savostyanov, Helena R. Slobodskaya, Sergey S. Tamozhnikov, Evgeny A. Levin, Alexander E. Saprigyn, Ekaterina A. Proshina, Tatiana N. Astakhova, Ekaterina A. Merkulova, Gennady G. Knyazev   +9 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source