Results 31 to 40 of about 318,792 (292)

Kluver-Bucy Syndrome after Meningoencephalitis

open access: yesPediatric Neurology Briefs, 2011
Researchers at Medical College of Georgia, Augusta, GA, report a 10-year-old girl with a history of Listeria monocytogenes meningoencephalitis, contracted at 2½ years of age, who developed behavioral changes consistent with Kluver-Bucy syndrome at 2 ...
J Gordon Millichap
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Developing a model of occupational therapy practice for children with attention deficit hyperactivity disorder (ADHD) [PDF]

open access: yes, 2005
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 15/06/2005.This three-stage study led to the development of a delineation model of occupational therapy practice for children with Attention Deficit ...
Chu, Sidney Kin Hoi
core   +5 more sources

Attention-deficit/hyperactivity disorder: a closer look [PDF]

open access: yes, 1999
Plan BThis paper examines Attention-Deficit Hyperactivity Disorder. More specifically, the aim of this paper is to discuss some of the many operational definitions of ADHD.
O'Neill, Michael J.
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

A study of an animal model of Attention-Deficit/ Hyperactivity Disorder using in vivo chronoamperometry and behavioural responses to methylphenidate and guanfacine [PDF]

open access: yes, 2010
Includes abstract.~Includes bibliographical references (leaves 119-147).Attention-Deficit/Hyperactivity Disorder (ADHD) is a childhood disorder that is behaviorally characterized by developmentally inappropriate levels of inattention, impulsivity and ...
Hsin-Wen Hsieh, Jennifer
core   +1 more source

Occupational therapy for children with attention deficit hyperactivity disorder (ADHD), Part 1: A delineation model of practice [PDF]

open access: yes, 2007
In the United Kingdom (UK), occupational therapy for children with attention deficit hyperactivity disorder (ADHD) is a small field of practice (Chu 2003a), even though 5% of school-aged children in the population are affected by the condition ...
Reynolds, F
core   +4 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Associations of Hyperactivity and Inattention Scores with Theta and Beta Oscillatory Dynamics of EEG in Stop-Signal Task in Healthy Children 7–10 Years Old

open access: yesBiology, 2021
In the current study, we aimed to investigate the associations between the natural variability in hyperactivity and inattention scores, as well as their combination with EEG oscillatory responses in the Stop-Signal task in a sample of healthy children ...
Andrey V. Bocharov   +9 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

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