Results 61 to 70 of about 318,792 (292)

Attention Deficit Hyperactivity Disorder (ADHD) and Ethnicity: A Literature Review [PDF]

, 2005
Attention Deficit Hyperactivity Disorder (ADHD) is one of the most expensive mental disorders, costing U.S. citizens $77 billion every year (Reinberg, 2004). Although ADHD effects between 3-7% of U.S.
Bryant, Shanel M.
core  

Post hoc analyses of the impact of previous medication on the efficacy of lisdexamfetamine dimesylate in the treatment of attention-deficit/hyperactivity disorder in a randomized, controlled trial [PDF]

, 2014
David R Coghill,1 Tobias Banaschewski,2 Michel Lecendreux,3 César Soutullo,4 Alessandro Zuddas,5 Ben Adeyi,6 Shaw Sorooshian7 1Division of Neuroscience, University of Dundee, Dundee, UK; 2Child and Adolescent Psychiatry and Psychotherapy, Central
Banaschewski T, Sorooshian S, Sorooshian, Shaw, Coghill DR, Lecendreux M, Coghill, DR, Soutullo, C, Soutullo, César, Banaschewski, Tobias, SOROOSHIAN S., Banaschewski, T, Adeyi, B, Coghill, David R., Zuddas, Alessandro, Adeyi B, Adeyi, Ben, Sorooshian, S, Zuddas A, Zuddas, A, Lecendreux, Michel, Lecendreux, M, Soutullo C   +21 more
core   +1 more source

Computation and Structure‐Guided Arginine Scanning Engineers a Hyperactive AP Endonuclease for Multiplex Viral RNA Sensing

Advanced Science, EarlyView.
Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang, Ting Wu, Feizuo Wang, Boyang Wang, Xin Yu Wong, Senfeng Zhang, Shengsheng Ma, Yao Liu, Fangyao Yao, Zhifeng Zeng, Siyuan Yang, Kunming Liu, Qi Wang, Yilong Wang, Yunxiang Zang, Xiaolong Wang, Xingxu Huang, Shao Li, Quanquan Ji, Tao Hu, Chunyi Hu   +20 more
wiley   +1 more source

Are language production problems apparent in adults who no longer meet diagnostic criteria for attention-deficit/hyperactivity disorder? [PDF]

, 2012
In this study, we examined sentence production in a sample of adults (N = 21) who had had attention-deficit/hyperactivity disorder (ADHD) as children, but as adults no longer met DSM-IV diagnostic criteria (APA, 2000).
Veld, Sean N., Sean N. Veld, Veld, Sean, Engelhardt, Paul, Fernanda Ferreira, Engelhardt, Paul E., Nigg, Joel T., Ferreira, Fernanda, Paul E. Engelhardt, Joel T. Nigg   +9 more
core   +1 more source

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

Advanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li, Xiao‐Bo Qian, Hai‐Long Zhang, Di Li, Ling Ji, Xin‐Chun Xu, Jia‐Sheng Ding, Li‐Jun Yin, Li Zhang, Guang‐Yin Xu, Rong Gao   +10 more
wiley   +1 more source

Attention deficit hyperactivity disorder: reframing “deficit” as creative strength

, 2012
Creative ideas are those that are both novel and useful. Creativity is considered to be a valuable social resource, which has supported the development of society in myriad domains.
Beaven, Alexandra
core   +1 more source

A Personalized Haplotype‐Resolved Near‐Gapless Genome Framework for Somatic Variant Discovery in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A patient‐specific, haplotype‐resolved genome framework improves detection and interpretation of somatic variants in hepatocellular carcinoma. Using multi‐platform sequencing, the personalized assembly resolves complex regions including centromeres and MHC/HLA loci, enhances structural variant discovery, and links regulatory alterations to allele ...
Jiazheng Lin, Yao Xiao, Shuangzi Luo, Yifan Li, Wenfei Zhang, Xiaoyu Zhang, Xinyi Wang, Di Wu, Jieru Hong, Yongkun Luan, Xun Huang, Yixiu Wang, Ningbo Wu, Xiaoxiao Hu, Fei Zhao, Wei Li, Xiao Luo, Bi Shi   +17 more
wiley   +1 more source

Leukodystrophy presenting as hyperactivity and bipolarity with uncommon adverse drug reaction

Indian Journal of Psychological Medicine, 2017
Leukodystrophy is a group of demyelinating neurodegenerative diseases of brain with varied presentation and multiple etiologies. Prognosis is predominantly dismal.
Roshan Sutar, Anirban Ray, Shekhar P Sheshadri   +2 more
doaj   +1 more source

Trajectories of growth and symptoms of attention-deficit/hyperactivity disorder in children : a longitudinal study [PDF]

, 2011
Background Empirical evidence suggests that prenatal growth is associated with attention deficit/hyperactivity disorder (ADHD) and its symptoms. Data on the importance of postnatal growth is, however scanty.
Dieter Wolke, Aulikki Lano, Kati Heinonen, Andersson Sture, Lano Aulikki, Eriksson Johan G, Andersson, Sture, Kajantie, Eero, Raikkonen, Katri, Johan G Eriksson, Eero Kajantie, Heinonen, Kati, Vartia Timo, Eriksson, Johan G., Räikkönen Katri, Sture Andersson, Timo Vartia, Heinonen Kati, Wolke Dieter, Vartia, Timo, Wolke, Dieter, Lano, Aulikki, Katri Räikkönen, Kajantie Eero, Pesonen Anu-Katriina, Anu-Katriina Pesonen, Pesonen, Anu-Katriina   +26 more
core   +2 more sources

USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis

Advanced Science, EarlyView.
This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui, Yuanlong Hu, Lin Lin, Lei Zhang, Chao Li, Yunlun Li   +5 more
wiley   +1 more source