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Primary Hyperaldosteronism

Medical Clinics of North America, 1988
Primary hyperaldosteronism is a challenging diagnosis because of its low incidence and variable pathophysiology. Serum potassium, properly done, is the routine screening test, but is not without its limitations. Confirmation of the diagnosis requires demonstration of abnormally high and nonsuppressible values for aldosterone in plasma and urine and low
R H, Noth, E G, Biglieri
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Primary Hyperaldosteronism

Endocrine Practice, 1997
To characterize the syndrome of primary aldosteronism and summarize diagnostic and therapeutic strategies.We review the mechanisms of action of aldosterone and outline features that distinguish the major subtypes of aldosteronism.The state of aldosterone excess should be suspected in every patient manifesting hypertension and hypokalemia.
M T, Laurel, U M, Kabadi
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Familial hyperaldosteronism

The Journal of Steroid Biochemistry and Molecular Biology, 2001
Primary aldosteronism (PAL) may be as much as ten times more common than has been traditionally thought, with most patients normokalemic. The study of familial varieties has facilitated a fuller appreciation of the nature and diversity of its clinical, biochemical, morphological and molecular aspects.
Stowasser, Michael, Gordon, Richard D.
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Primary Hyperaldosteronism

Experimental and Clinical Endocrinology & Diabetes, 2002
Primary hyperaldosteronism (PHA) is regarded as a rare disease with prevalence rates of 0.5 to 2% within the hypertensive population. Recent studies using more detailed screening procedures in small hypertensive cohorts have suggested that PHA may be more common than previously thought (3-18%).
M, Quinkler, J, Lepenies, S, Diederich
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Normotensive secondary hyperaldosteronism

The Journal of Pediatrics, 1965
The case of a 2 1/2 year old boy is reported in which a separation of the dual effects ofangiotensin II were demonstrated: elevation of systemic blood pressure and stimulation of aldosterone secretion. The patient had hypokalemia, hyposthenuria, and growth retardation.
A J, Greenberg   +3 more
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Dexamethasone-Suppressible Hyperaldosteronism

The Journal of Clinical Endocrinology & Metabolism, 1973
Reinvestigation of an 18-yr-old male patient with dexamethasone-suppressible hyperaldosteronism after 6 yr of little or no treatment demonstrates that elevated blood pressure and increased urinary aldosterone excretion still were promptly decreased by a small dose of dexamethasone.
M I, New, E J, Siegal, R E, Peterson
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Diabetes in Hyperaldosteronism

2014
Primary aldosteronism (PA) is the most common cause of endocrine hypertension. PA is a heterogeneous disease, which can be divided into various different subtypes. The mechanisms through which aldosterone exerts an effect on glucose and insulin metabolism are different.
Crudo V   +3 more
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Diagnosis of Hyperaldosteronism

Endocrinology and Metabolism Clinics of North America, 1991
Hyperaldosteronism is associated with hypertension, potassium depletion, and suppressed plasma renin activity. It may involve one or both adrenal glands. This article reviews the different types of hyperaldosteronism and the diagnosis and management of each.
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Feline Primary Hyperaldosteronism

Veterinary Clinics of North America: Small Animal Practice, 2010
Primary hyperaldosteronism (PHA) is being recognized more frequently in cats. Usual hallmarks of the disease include hypokalemia and systemic hypertension. Ultrasound frequently detects an abnormality in the affected adrenal gland. Diagnosis is based on increased plasma or serum aldosterone concentrations, particularly in the face of hypokalemia and ...
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