Results 71 to 80 of about 114,297 (258)

Discordance Between Japanese and European Definitions of Acute‐on‐Chronic Liver Failure in Alcohol‐Related Cirrhosis: Insights From a 10‐Year Consecutive Cohort

Hepatology Research, EarlyView.
Substantial discordance was observed between Japanese and EASL‐CLIF definitions of acute‐on‐chronic liver failure in alcohol‐related cirrhosis. Many Japanese‐defined cases were classified as EASL‐CLIF grade 0 yet retained non‐negligible 1‐year mortality, highlighting the complementary roles of hepatic‐based and organ failure–based frameworks.
Hidehiro Kamezaki, Nana Yamada, Terunao Iwanaga, Takafumi Sakuma, Koji Takahashi, Junichi Senoo, Makoto Arai, Tatsuo Kanda, Sadahisa Ogasawara, Jun Kato   +9 more
wiley   +1 more source

Gilbert Syndrome with Concomitant Hereditary Spherocytosis Presenting with Moderate Unconjugated Hyperbilirubinemia

Internal Medicine, 2017
We experienced a case of a 19-year-old man with Gilbert syndrome with concomitant hereditary spherocytosis. The patient presented with moderate unconjugated hyperbilirubinemia, and inherited etiology was strongly suspected. The diagnosis of Gilbert syndrome was confirmed by the genetic analysis of the UGT1A1 gene, demonstrating UGT1A1*28 and compound ...
Aiso, Mitsuhiko, Yagi, Minami, Tanaka, Atsushi, Miura, Kotaro, Miura, Ryo, Arizumi, Toshihiko, Takamori, Yoriyuki, Nakahara, Sayuri, Maruo, Yoshihiro, Takikawa, Hajime   +9 more
openaire   +4 more sources

Circulating miR‐342‐3p as a biomarker for diagnosing gestational diabetes mellitus and predicting adverse perinatal outcomes: A retrospective cohort study

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims This study evaluated the clinical utility of circulating miR‐342‐3p for diagnosing gestational diabetes mellitus (GDM) and predicting adverse perinatal outcomes (APOs). Methods A retrospective cohort of 261 GDM women (the GDM group) and 261 propensity score‐matched healthy controls (the Normal group) was analyzed.
Kangjun Yu, Sanqiang Niu, Hai Liang
wiley   +1 more source

HEREDITARY SPHEROCYTOSIS IN MOTHER AND NEONATE DIAGNOSED BY ANEMIA AND HYPERBILIRUBINEMIA IN THE NEONATE

, 2003
We experienced a case of hereditary spherocytosis in both mother and neonate diagnosed by anemia and hyperbilirubinemia in the neonate. Phototherapy was effective against the neonatal jaundice ; however, anemia became severe and necessitated a blood ...
Ando, Yoshiya, Matsumoto, Yoshinari, Matsuda, Tetsunori, Otakara, Mormlto, Kakimoto, Kazuhiro   +4 more
core   +1 more source

Misdiagnosis of hereditary amyloidosis as AL (Primary) amyloidosis [PDF]

, 2002
Background: Hereditary, autosomal dominant amyloidosis, caused by mutations in the genes encoding transthyretin, fibrinogen A -chain, lysozyme, or apolipoprotein A-I, is thought to be extremely rare and is not routinely included in the differential ...
Booth, D.R., Gilbertson, J.A., Hawkins, P.N., Booth, S.E., Lachmann, H.J., Gillmore, J.D., Bybee, A., Pepys, M.B.   +7 more
core  

Extended microsatellite analysis in microsatellite stable, MSH2 and MLH1 mutation-negative HNPCC patients: Genetic reclassification and correlation with clinical features [PDF]

, 2004
Background: Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominant disorder predisposing to predominantly colorectal cancer (CRC) and endometrial cancer frequently due to germline mutations in DNA mismatch repair (MMR) genes, mainly ...
Gross, M., Lohse, P., Muders, M., Müller-Koch, Y., Daum, J., Mussack, T., Baretton, G., Kopp, R., Schiemann, Uwe, Holinski-Feder, E.   +9 more
core   +1 more source

Illuminating Connections: Exploring the Dynamic Relationship Between Phototherapy and the Skin

Pediatric Dermatology, EarlyView.
ABSTRACT The neonatal period represents a critical window for skin barrier maturation, microbial colonization, and immune development. As such, early‐life exposures may exert lasting effects on dermatologic and systemic health. A common early‐life exposure is blue light phototherapy (BLP), a life‐saving treatment for neonatal hyperbilirubinemia ...
Meshi Paz, Peter Lio
wiley   +1 more source

Multiorgan Dysfunction and Associated Prognosis in Transthyretin Cardiac Amyloidosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Transthyretin cardiac amyloidosis (ATTR‐CA) is a progressive and ultimately fatal cardiomyopathy. Biomarkers reflecting multiorgan dysfunction are of increasing importance in patients with heart failure; however, their significance in ATTR‐CA ...
Adam Ioannou, Christian Nitsche, Aldostefano Porcari, Rishi K. Patel, Yousuf Razvi, Muhammad U. Rauf, Ana Martinez‐Naharro, Lucia Venneri, Antonella Accietto, Lucrezia Netti, Francesco Bandera, Ruta Virsinskaite, Tushar Kotecha, Dan Knight, Aviva Petrie, Carol Whelan, Ashutosh Wechalekar, Helen Lachmann, Philip N. Hawkins, Julian D. Gillmore, Marianna Fontana   +20 more
doaj   +1 more source

Breakthrough Hemolysis in Paroxysmal Nocturnal Hemoglobinuria: Mechanistic Insights and Management Strategies

Transfusion, EarlyView.
Abstract Background Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal hematopoietic stem cell disorder caused by somatic mutations in the PIGA gene, resulting in loss of glycosylphosphatidylinositol (GPI)‐anchored proteins, including the complement regulatory proteins, CD55 and CD59.
Ganesh Raman, Meghana Vivek, Rida Hasan, Siobán Keel, Laura Connelly‐Smith   +4 more
wiley   +1 more source

Assembly of Bioactive Superstructures via Metal–Phenolic Complexation for Blood Purification

Angewandte Chemie, Volume 138, Issue 40, 28 September 2026.
Bioactive superstructures are assembled via metal–phenolic‐mediated assembly on agarose templates, followed by modification with human serum albumin. These superstructures demonstrate high bilirubin adsorption efficiency, strong antibacterial activity, and anticoagulant activity, providing a strategy for the rational design of multifunctional blood ...
Po Wang, Jingqu Chen, Siying Chen, Binsha Peng, Zhifeng Zhou, Ling Zhang, Rui Xie, Xiaojie Ju, Wei Wang, Dawei Pan, Liangyin Chu, Frank Caruso, Zhuang Liu   +12 more
wiley   +2 more sources