Results 71 to 80 of about 5,947 (218)

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason, John P. Woodhouse, Joanna S. Yi, M. Monica Gramatges, Olga A. Taylor, Veronica A. Morales, Shalini Dhamodharan, Marley Roberts, Karen R. Rabin, Philip J. Lupo, Michael E. Scheurer, Van Huynh, Steven D. Mittelman, Etan Orgel, Austin L. Brown   +14 more
wiley   +1 more source

TGA/Chemometric Test Is Able to Detect the Presence of a Rare Hemoglobin Variant Hb Bibba

Frontiers in Molecular Biosciences, 2019
In this study the TGA/Chemometric test was applied for diagnosis of a case of congenital hemolytic anemia for which the common first level diagnostic tests were not able to find the erythrocyte congenital defect.
Roberta Risoluti, Patrizia Caprari, Giuseppina Gullifa, Loretta Diana, Matteo Luciani, Antonio Amato, Stefano Materazzi   +6 more
doaj   +1 more source

First Reported Case of Fulminant Weil's Disease in South Khorasan, Eastern Iran: Diagnostic Challenges in a Non‐Endemic Region and Implications for Military Deployment

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Weil's disease should be considered even in non‐endemic regions when compatible clinical findings are accompanied by relevant exposure history. This case is epidemiologically notable as the first documented report from South Khorasan Province, highlighting the diagnostic challenges of leptospirosis in non‐endemic settings and the potential ...
Zohreh Azarkar, Anahita Arian, Motahareh Mahi‐Birjand, Parvin Askari   +3 more
wiley   +1 more source

Salvage Therapy With Inotuzumab Ozogamicin in Relapsed/Refractory B‐ALL After CAR‐T Therapy and HSCT: A Case Series

Cancer Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background Although inotuzumab ozogamicin (InO) has been approved as an effective agent for patients with refractory/relapsed (r/r) B‐cell acute lymphoblastic leukemia (B‐ALL), data in the context of post chimeric antigen receptor (CAR)‐T cell therapy and allogeneic hematopoietic stem cell transplantation (allo‐HSCT) relapse are lacking.
Honghu Li, Luxin Yang, Lizhen Liu, Xiaoyu Lai, Lixia Zhu, Kui Zhao, Qian Luo, He Huang, Yi Luo   +8 more
wiley   +1 more source

Hereditary Spherocytosis

, 2014
Hereditary Spherocytosis (HS) is a hemolytic anemia where red blood cell membranes are spherical unlike common red blood cells, which are flat and round.
Loeser, Dolores
core   +1 more source

Table1_Case report: A rare case of pyruvate kinase deficiency and Crigler-Najjar syndrome type II with a novel pathogenic variant of PKLR and UGT1A1 mutation.pdf

, 2023
Pyruvate Kinase Deficiency (PKD) and Crigler-Najjar syndrome are rare autosomal recessive liver diseases. PKD is caused by homozygous or compound heterozygous mutations in the PKLR gene, leading to non-spherocytic hereditary hemolytic anemia.
Long Wu, Huan Wu (617276), Huan Wu, Bao-fang Zhang (5586845), Bao-fang Zhang, Quan Zhang, Long Wu (655081), Quan Zhang (168081)   +7 more
core   +1 more source

A challenging diagnosis of hereditary microspherocytosis (Minkowski-Chauffard disease) in a child (a case report)

Сучасна педіатрія: Україна
Hereditary microspherocytosis (HM) is an inherited hemolytic anemia associated with erythrocyte membrane abnormalities which should be suspected in patients with a triad of symptoms: anemia, jaundice, and splenomegaly.
L.I. Vakulenko, A.V. Riznyk
doaj   +1 more source

Silent Risks in the Blood Supply: Co‐Inherited Glucose‐6‐Phosphate Dehydrogenase Deficiency and Sickle Cell Trait Among Donors at the Cape Coast Teaching Hospital, Ghana: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims Blood transfusion saves lives, but red cell enzymopathies and hemoglobin variants can reduce red cell survival under oxidative stress. In sub‐Saharan Africa, blood donors are not routinely screened for glucose‐6‐phosphate dehydrogenase (G6PD) deficiency or sickle cell trait (SCT).
Bashirudeen Kofi Mensa Essel, Walter Quarm, Comfort Fynn, Rebecca Peniel Storph, Evans Duah, Edward Morkporkpor Adela, Emmanuel Ofori, Nana Benyin Aidoo, Patrick Adu   +8 more
wiley   +1 more source

Real‐world progression‐free survival and overall survival in patients with HR+/HER2− advanced breast cancer treated in first‐line with ribociclib, endocrine monotherapy or chemotherapy: Results from the observational RIBANNA study

International Journal of Cancer, Volume 159, Issue 1, Page 210-223, 1 July 2026.
What's New? The CDK4/6 inhibitor ribociclib in combination with an endocrine‐based therapy has demonstrated significant progression‐free and overall survival benefits in patients with advanced/metastatic HR+/HER2‐ breast cancer in the pivotal MONALEESA trials.
Peter A. Fasching, Cosima Brucker, Thomas Decker, Anne Engel, Thomas Göhler, Christian Jackisch, Jan Janssen, Andreas Köhler, Kerstin Lüdtke‐Heckenkamp, Diana Lüftner, Frederik Marmé, Marion van Mackelenbergh, Beate Rautenberg, Marcus Schmidt, Rudolf Weide, Pauline Wimberger, Elena Kisseleff, Christina Pfister, Claudia Quiering, Christian Roos, Achim Wöckel   +20 more
wiley   +1 more source

Etiological analyses of marked neonatal hyperbilirubinemia in a single institution in Taiwan

, 2012
[[abstract]]Background: Hyperbilirubinemia is a common disorder during the neonatal period. Severe neonatal hyperbilirubinemia (NH) carries a potential for permanent neurological impairment.
Cheng, SW;Chiu, YW;Weng, YH
core