Results 101 to 110 of about 66,582 (323)

Opportunities and Challenges of Population Pharmacogenomics

Annals of Human Genetics, EarlyView.
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou, Yoomi Park, Mahamadou D. Camara, Volker M. Lauschke   +3 more
wiley   +1 more source

Decreased dentin tubules density and reduced thickness of peritubular dentin in hyperbilirubinemia-related green teeth [PDF]

, 2017
It is stated anecdotally that patients with liver diseases in childhood who develop green teeth have increased risk for rampant caries, which may be secondary to changes in dental structure.
Alves, Fabio A., Antunes, Alberto, Giannini, Marcelo, Goes, Mario Fernando, Lopes, Márcio Ajudarte, Machado, José Lécio, Neves-Silva, Rodrigo, Paes Leme, Adriana Franco, Santos Silva, Alan Roger, Tenório, Maria-Dânia   +9 more
core   +1 more source

Analysis of the intestinal microbiota and profiles of blood amino acids and acylcarnitines in neonates with hyperbilirubinemia

BMC Microbiology
Objective This study aimed to discuss the distinctive features of the intestinal microbiota in neonates with hyperbilirubinemia and to comprehensively analyse the composition of the intestinal microbiota as well as the levels of free amino acids and ...
Junguo Li, Shenglin Ye, Xinyuan Huang, Guolong Yang, Yijin Wang, Jianghui Zeng, Chunhui Lai   +6 more
doaj   +1 more source

Postprandial Hyperglycaemia Screening and Pregnancy Outcomes‐Lessons From COVID ‐19

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background During COVID‐19, the diagnosis and treatment of GDM differed from conventional criteria. In Australia, during the alternative testing period, women with fasting glucose < 4.7 mmol/L were not diagnosed with GDM. Aim To describe the maternal and neonatal outcomes of pregnant women with fasting blood glucose < 4.7 mmol/L for whom the ...
Beenu Bastian, Lisa Gaye Smithers, Ansar Kunjunju, Alexia Pape, Monique Francois   +4 more
wiley   +1 more source

Factors Affecting the Relationship Between Total and Unbound Bilirubin in Preterm and Term Infants

Acta Paediatrica, EarlyView.
ABSTRACT Aim Newborn infants universally experience jaundice, most of which is physiologic, but in some high‐risk situations, it may lead to neurological dysfunction or death. Unbound bilirubin (Bf) may be the best predictor of bilirubin toxicity in this population. The goal of the study is to examine the relationship between total serum bilirubin (TSB)
Thomas Hegyi, Dalya Chefitz, Alan Weller, Andrew Huber, Mary Carayannopoulos, William Oh, Alan Kleinfeld   +6 more
wiley   +1 more source

Systemic lupus erythematosus‐associated autoantibodies in sickle cell disease: Spontaneous emergence in a patient and in transgenic sickle mice

British Journal of Haematology, Volume 206, Issue 4, Page 1213-1217, April 2025.
Summary We describe a patient with sickle cell disease (SCD) and elevated antiphospholipid antibodies (aPL) who developed multi‐organ failure resembling catastrophic antiphospholipid syndrome. Autoimmune screening revealed several autoantibodies characteristic of systemic lupus erythematosus (SLE). Notably, routinely housed and unmanipulated transgenic
Urshita Sinha, Suman Setty, Céleste Pilon, Julia J. Brown, Maria Armila Ruiz, Guohui Ren, Joyce Rauch, Santosh L. Saraf, Jerrold S. Levine   +8 more
wiley   +1 more source

Successful Pregnancy Outcome In Maternal Crigler Najjar Syndrome Type II. [PDF]

, 2012
Estimated incidence of Crigler-Najjar syndrome(CNS) is 1 case per 1,000,000 births(1 million). The overall prevalence of CN syndrome is unknown, with only several hundred people reported to have this disease.
Padmalatha, VV, Poornima, M, Rao, SR, Shakuntala, PN   +3 more
core  

Neonatal hyperbilirubinemia and Rhesus disease of the newborn: incidence and impairment estimates for 2010 at regional and global levels. [PDF]

, 2013
BACKGROUND: Rhesus (Rh) disease and extreme hyperbilirubinemia (EHB) result in neonatal mortality and long-term neurodevelopmental impairment, yet there are no estimates of their burden.
Bell, Jennifer, Bhutani, Vinod K, Blencowe, Hannah, Cousens, Simon, de Almeida, Maria-Fernanda, Du, Lizhong, Ebbesen, Finn, Fahmy, Nahed, Khanna, Rajesh, Kumar, Praveen, Lawn, Joy E, Mori, Rintaro, Okolo, Angela A, Olusanya, Bolajoko O, Paul, Vinod K, Sgro, Michael, Slusher, Tina M, Zipursky, Alvin   +17 more
core   +2 more sources

Umbilical Cord Blood Bilirubin as a Predictor of Significant Hyperbilirubinemia Requiring Phototherapy among Full-term Healthy Neonates: A Prospective Study [PDF]

Indian Journal of Medical Biochemistry
Aim and background: Jaundice is a clinical condition characterized by transient bilirubin conjugation deficiency resulting in neonatal hyperbilirubinemia.
Preethi B Patil, Prasanna Saka, Abhay K Chidananda   +2 more
doaj   +1 more source

Umbilical cord blood bilirubins, gestational age, and maternal race predict neonatal hyperbilirubinemia

PLoS ONE, 2018
Objective No validated biomarker at birth exists to predict which newborns will develop severe hyperbilirubinemia. This study’s primary aim was to build and validate a prediction model for severe hyperbilirubinemia using umbilical cord blood bilirubins ...
A. Castillo, T. Grogan, G. Wegrzyn, Karrie V. Ly, V. Walker, K. Calkins   +5 more
semanticscholar   +1 more source