Use of Denosumab in Children With Osteoclast Bone Dysplasias: Report of Three Cases. [PDF]
Denosumab has been used successfully to treat disease-associated osteoclast overactivity, including giant cell tumor of bone. Given its mechanism of action, denosumab is a potent potential treatment of other osteoclast bone dysplasias including central ...
Bernthal, Nicholas M +8 more
core +2 more sources
Severe hypercalcemia is a rare metabolic disorder in pediatric medicine. This report describes a rare case of severe hypercalcemia and its clinical manifestations in a 2-year-old toddler.
Jose Colleti Junior +5 more
doaj +1 more source
A successful treatment of hypercalcemia with zoledronic acid in a 15-year-old boy with acute lymphoblastic leukemia [PDF]
Severe hypercalcemia in children is a rare medical emergency. We present a case of a 15-year-old boy with hypercalcemia (total calcium level, 14.2 mg/dL) with a normal complete blood count, no circulating blasts in the peripheral blood film, and no other
Hye-Jin Park +2 more
doaj +1 more source
Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis [PDF]
BACKGROUND: Treatment with glucocorticoids is associated with bone loss starting soon after therapy is initiated and an increased risk of fracture. METHODS: We performed a randomized, double-placebo, double-blind clinical trial of 18 months' duration ...
Ale Algra +14 more
core +4 more sources
Severity of Ionized Hypercalcemia and Hypocalcemia Is Associated With Etiology in Dogs and Cats
Background: Calcium disorders are common in small animals, but few studies have investigated the etiology of ionized hypercalcemia and hypocalcemia in large populations. This study aimed to determine the incidence of ionized calcium disorders in dogs and
Michelle Coady +2 more
doaj +1 more source
Sarcoidosis presenting as granulomatous myositis in a 16-year-old adolescent [PDF]
BACKGROUND: Sarcoidosis is a multi-system disease characterized by the presence of non-caseating epithelioid granulomas in affected tissues, including skeletal muscle.
Eutsler, Eric Eutsler +4 more
core +2 more sources
Can atorvastatin calcium cause asymptomatic hypercalcemia?
The use of statins may have unnatural effects. A 54-year-old woman was admitted to the hospital with an incidental finding of hypercalcemia (10.8 mg/dL). There was no disease other than hyperlipidemia, and the patient had been on a course of atorvastatin
Suleyman Hilmi Ipekci +3 more
doaj +1 more source
Prevalence of hypercalcemia in primary hypoadrenocorticism in dogs: Multicenter, retrospective study
Background Hypoadrenocorticism is an important differential for hypercalcemia. The etiology of hypercalcemia in hypoadrenocorticism in dogs is unclear.
Harriet Hall +6 more
doaj +1 more source
The Effect of Moderate Dietary Protein and Phosphate Restriction on Calcium-Phosphate Homeostasis in Healthy Older Cats [PDF]
Background Dietary phosphate and protein restriction decreases plasma PTH and FGF‐23 concentrations and improves survival time in azotemic cats, but has not been examined in cats that are not azotemic.
Antoniucci +51 more
core +3 more sources
Here we describe, to our knowledge, the first case where an evolution of mechanisms responsible for hypercalcemia occurred in undifferentiated thymic carcinoma and discuss specific management strategies for hypercalcemia of malignancy (HCM).
Cheng Cheng +2 more
doaj +1 more source

