Results 21 to 30 of about 88,811 (347)
Vitamin D-Mediated Hypercalcemia: Mechanisms, Diagnosis, and Treatment.
Hypercalcemia occurs in up to 4% of the population in association with malignancy, primary hyperparathyroidism, ingestion of excessive calcium and/or vitamin D, ectopic production of 1,25-dihydroxyvitamin D [1,25(OH)2D], and impaired degradation of 1,25 ...
P. Tebben, Ravinder J Singh, R. Kumar
semanticscholar +1 more source
The most common cause of hypercalcemia in hospitalized patients is malignancy. Primary hyperparathyroidism most commonly causes hypercalcemia in the outpatient setting. These two account for over 90% of all cases of hypercalcemia.
Jelena Maletkovic+4 more
doaj +1 more source
Cellular and molecular mediators of bone metastatic lesions [PDF]
Bone is the preferential site of metastasis for breast and prostate tumor. Cancer cells establish a tight relationship with the host tissue, secreting factors that stimulate or inhibit bone cells, receiving signals generated from the bone remodeling ...
Battafarano, Giulia+3 more
core +2 more sources
Hypercalcemia and cancer: Differential diagnosis and treatment
Incidentally detected hypercalcemia usually presents in an indolent manner and is most likely caused by primary hyperparathyroidism. In contrast, hypercalcemia in the patient with a history of cancer presents in a wide range of clinical settings and may ...
Jonathan Zagzag+3 more
semanticscholar +1 more source
Severe hypercalcemia is a rare metabolic disorder in pediatric medicine. This report describes a rare case of severe hypercalcemia and its clinical manifestations in a 2-year-old toddler.
Jose Colleti Junior+5 more
doaj +1 more source
Hypercalcemia is a common metabolic abnormality in children and generally occurs due to hyperparathyroidism, vitamin D toxicity, some genetic disorders and malignant diseases.
Suna Kılınç+5 more
doaj +1 more source
Ionized hypercalcemia in 238 cats from a referral hospital population (2009‐2019)
Background Ionized calcium concentration ([iCa]) is more sensitive for detecting calcium disturbances than serum total calcium concentration but literature on ionized hypercalcemia in cats is limited.
Sophie E. Broughton+3 more
doaj +1 more source
AIMS OF THE STUDY: To investigate the prevalence of hypercalcemia (>2.60 mmol/l) and severe hypercalcemia (≥2.80 mmol/l) on admission. Symptoms, causes, course of serum calcium, treatment and outcome of severe hypercalcemia were evaluated and compared ...
Svenja Ravioli+4 more
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Diagnosis, Pathophysiology and Management of Hypercalcemia in Malignancy: A Review of the Literature
Hypercalcemia of malignancy is the most common life-threatening metabolic disorder in patients with advanced stage cancers and is a sign of poor prognosis. It usually presents with markedly elevated calcium level and is severely symptomatic.
Nikolaos Asonitis+5 more
semanticscholar +1 more source
A successful treatment of hypercalcemia with zoledronic acid in a 15-year-old boy with acute lymphoblastic leukemia [PDF]
Severe hypercalcemia in children is a rare medical emergency. We present a case of a 15-year-old boy with hypercalcemia (total calcium level, 14.2 mg/dL) with a normal complete blood count, no circulating blasts in the peripheral blood film, and no other
Hye-Jin Park+2 more
doaj +1 more source