Results 151 to 160 of about 38,999 (275)

Gene Expression Profiling of Pancreatic Ductal Adenocarcinoma Cells in Hypercapnia Identifies SIAH3 as a Novel Prognostic Biomarker

Hypercapnia is a key feature of the respiratory microenvironment in many pathologic conditions. It occurs both as a regional and as a systemic process, and it is associated with multiple metabolic changes such as mitochondrial dysfunction, decreased ATP ...
Aditi Jain, Charles J. Yeo, Nitzan Zohar, Ryan Maguire, Harish Lavu, Dmitriy Bosykh, Avinoam Nevler, Saed Khalilieh, Wilbur B. Bowne   +8 more
core   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Oxygen, carbon dioxide, and nitric oxide: role in the pathophysiology of obstructive sleep apnea. [PDF]

Med Gas Res
Fabozzi A, Tondo P, Antonaglia C, Steffanina A, Lacedonia D, Confalonieri M, Bonini M, Palange P.   +7 more
europepmc   +1 more source

Elevated carotid body tonic activity contributes to ventilatory acclimatization and de‐acclimatization to high altitude at rest and during exercise

The Journal of Physiology, EarlyView.
Abstract figure legend Participants spent 13 days at high altitude (3800 m), where the reduced inspired oxygen pressure (↓PiO2$ \downarrow {P_{{\mathrm{i}}{{\mathrm{O}}_2}}}$) which elicited ventilatory acclimatization and increased inhibition of ventilation by transient hyperoxia (ΔV̇E$\Delta {\dot V_{\mathrm{E}}}$).
Ayechew A. Getu, L. Madden Brewster, Travis D. Gibbons, James D. Anholm, Michael Stembridge, Philip N. Ainslie, Jay M. J. R. Carr   +6 more
wiley   +1 more source

Severe Hypercapnia and Hemodynamic Instability During Carbon Dioxide Insufflation During Robot-Assisted Thoracic Surgery. [PDF]

Cureus
Watanabe M, Shiraha N, Shikatani Y, Uehara K.   +3 more
europepmc   +1 more source

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

The Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

Supraphysiological ascorbic acid infusion attenuates cerebrovascular dysfunction in middle-aged and older adults. [PDF]

Physiol Rep
DeConne TM, Sanjana F, Habash EM, Decker KP, Nichols W, Hobson JC, Rizzi NA, Martens CR.   +7 more
europepmc   +1 more source

Intrinsic pH chemosensitivity of acutely dissociated medullary serotonergic and retrotrapezoid neurones

The Journal of Physiology, EarlyView.
Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu, Eduardo Bravo, George Bradley Richerson   +2 more
wiley   +1 more source

Holter-Detected Arrhythmias in Acute Exacerbations of COPD: NT-proBNP Correlates and Hypercapnia Associated with COPD-Related Readmission. [PDF]

Int J Chron Obstruct Pulmon Dis
Ding N, Chen J, Qiu W, Lu Y, Chen Z, Cai R, Chen A.   +6 more
europepmc   +1 more source

Acid-Base Phenotypes in Sedative Toxidrome: Characterisation, Agent-Specific Patterns and Clinical Associations. [PDF]

Emerg Med Australas
Chandru P, Gunja N.
europepmc   +1 more source