Results 151 to 160 of about 38,036 (248)

CO2 chemoreflex contributions to ventilatory long‐term facilitation

The Journal of Physiology, EarlyView.
Abstract figure legend To determine whether changes in CO2 chemoreflex sensitivity contribute to ventilatory long‐term facilitation (LTF), we tested the hypothesis that hypercapnic acute intermittent hypoxia (AIH) induces ventilatory LTF and enhances peripheral, but not central, chemoreceptor CO2 chemoreflex sensitivity.
Susan V. Cross, Elizabeth Keen, Tom E. Nightingale, Zubair Ahmed, George M. Balanos, Joseph F. Welch   +5 more
wiley   +1 more source

Hypercapnia enhances airway smooth muscle contractility via STIM1-dependent Ca2+ signaling. [PDF]

JCI Insight
Shigemura M, Kryvenko V, Pacheco JA, Puckelwartz MJ, Aleksic M, Magnani ND, Thompson E, Martin-Romero FJ, Cummins EP, Seeger W, Bräuninger A, Welch LC, Budinger GRS, Lecuona E, Dada LA, Bharat A, Vadász I, Prakriya M, Sznajder JI.   +18 more
europepmc   +1 more source

Electrophysiological properties of the dorsal motor nucleus of the vagus motoneurones controlling airway mucus secretion in rats

The Journal of Physiology, EarlyView.
Abstract figure legend Acidosis depolarises parasympathetic respiratory motoneurones in the dorsal motor nucleus of the vagus (DMV) and increases their firing frequency by reducing TWIK‐2 channel conductance. Acidosis also activates astrocytes, which further enhance neuronal excitability through NMDA receptor‐dependent glutamatergic signalling.
Daniel P. de Souza, Renato W. Martins Sá, Luiza Henrique de Souza, Fernando S. Ramalho, Davi J. A. Moraes   +4 more
wiley   +1 more source

Hypothalamic Glutamatergic/Orexinergic Neurons Attenuate Fentanyl-Induced Respiratory Depression via Medullary Pre-BöTzinger Complex Pathways. [PDF]

J Neurosci
Arakawa H, Arakawa K, Levitt ES.
europepmc   +1 more source

Beyond nocturnal hypercapnia: positioning obstructive sleep apnoea within a sleep-circadian-hypothalamic network. [PDF]

Eur Respir Rev
Lin YH, Lin KJ, Chen JY.
europepmc   +1 more source

Third Space Endoscopic Therapies for Benign Motility Disorders: A Narrative Review

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives To review the evidence base, evolution, outcomes, adverse events (AEs), and management for third‐space endoscopy (TSE) procedures for management of benign motility disorders. Methods This review examines TSE procedures for motility disorders, reviewing the current available techniques, success, outcomes, and long‐term outcomes from ...
Sanjana Bhagwat, Amol Bapaye
wiley   +1 more source

Molecular and Cellular Signaling Pathways of the Effects of Hypoxia and Hypercapnia on the Mechanisms of Neuroinflammation. [PDF]

Int J Mol Sci
Chekulaev PA, Zembatov GM, Namiot ED, Alekseeva TM, Ternovykh IK, Manasova ZS, Kulikov VP, Andriutsa NS, Tregub PP.   +8 more
europepmc   +1 more source

Respiratory Support With Nasal High Flow Reduces Opioid Requirements During Endoscopic Retrograde Cholangiopancreatography

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Nasal high flow (NHF) improves oxygenation, reduces the work of breathing, and stabilizes ventilation. In endoscopic retrograde cholangiopancreatography (ERCP) under dexmedetomidine‐based sedation, opioids are often required but increase the risk of respiratory depression and delayed recovery.
Tomotaka Mori, Takao Ayuse, Shuntaro Sato, Taiga Ichinomia, Rintaro Yano, Akane Shimakura, Yasuhiko Nakao, Kosuke Takahashi, Masanori Fukushima, Masafumi Haraguchi, Ryu Sasaki, Eisuke Ozawa, Satoshi Miuma, Stanislav Tatkov, Tetsuya Hara, Hisamitsu Miyaaki   +15 more
wiley   +1 more source

Defying An Ominous Sign: Complete Neurological Recovery after Bilateral Fixed Dilated Pupils in Hypercapnic Respiratory Failure. [PDF]

Eur J Case Rep Intern Med
Naimer SA.
europepmc   +1 more source

Avian Eggshell Evolutionary Adaptations Inform Biomimetic Strategies for Next‑Generation Precision Cancer Theranostics

Advanced Oncology, Volume 1, Issue 1, December 2026.
ABSTRACT The avian eggshell is a sophisticated, multi‐functional biocomposite and, more importantly, an autonomous life‐support system evolved to safeguard embryonic development across dynamic and hostile environments. Discussing eggshell‐inspired biomaterials beyond simple structural imitation, this review translates these evolutionary survival ...
Zhiqiang Liu, Sida Ling, Mengqi Zhao, Chunyan Zhu, Yaoye Zhou, Hengquan Hou, Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Zuyong Wang, Swee Hin Teoh   +11 more
wiley   +1 more source