CO2 chemoreflex contributions to ventilatory long‐term facilitation
Abstract figure legend To determine whether changes in CO2 chemoreflex sensitivity contribute to ventilatory long‐term facilitation (LTF), we tested the hypothesis that hypercapnic acute intermittent hypoxia (AIH) induces ventilatory LTF and enhances peripheral, but not central, chemoreceptor CO2 chemoreflex sensitivity.
Susan V. Cross +5 more
wiley +1 more source
Erythroid anion exchanger-1 (SLC4A1) modulates carbonic anhydrase inhibitor acetazolamide on respiration. [PDF]
Lai CT +5 more
europepmc +1 more source
Abstract figure legend Acidosis depolarises parasympathetic respiratory motoneurones in the dorsal motor nucleus of the vagus (DMV) and increases their firing frequency by reducing TWIK‐2 channel conductance. Acidosis also activates astrocytes, which further enhance neuronal excitability through NMDA receptor‐dependent glutamatergic signalling.
Daniel P. de Souza +4 more
wiley +1 more source
Altitude‐induced plasticity of respiratory central–peripheral chemoreflex interaction
Abstract figure legend Altitude‐induced plasticity of respiratory central–peripheral chemoreflex interaction. Seventeen participants completed modified rebreathing tests at low altitude and after 7–10 days of acclimatization at high altitude (3500 m). Central chemoreceptor activation was isolated using hypercapnic hyperoxia (end‐tidal PO2${{P}_{{{O}_2}}
Nasimi A. Guluzade +4 more
wiley +1 more source
Central hypoventilation with hypercapnia: the silent face of ventilatory control. [PDF]
Marques IMB, Lafetá ML, Ferreira EVM.
europepmc +1 more source
Genetic variants at immunoglobulin and mitochondrial loci associated with chronic hypercapnia in chronic obstructive pulmonary disease. [PDF]
Boersma R +9 more
europepmc +1 more source
Third Space Endoscopic Therapies for Benign Motility Disorders: A Narrative Review
ABSTRACT Objectives To review the evidence base, evolution, outcomes, adverse events (AEs), and management for third‐space endoscopy (TSE) procedures for management of benign motility disorders. Methods This review examines TSE procedures for motility disorders, reviewing the current available techniques, success, outcomes, and long‐term outcomes from ...
Sanjana Bhagwat, Amol Bapaye
wiley +1 more source
Chronic Hypercapnic Respiratory Failure in COPD in Lithuania: National Registry Trends and Prehospital Emergency-Care Professionals' Knowledge of Hypercapnia and Oxygen Therapy. [PDF]
Gauronskaitė R +3 more
europepmc +1 more source
ABSTRACT Objectives Nasal high flow (NHF) improves oxygenation, reduces the work of breathing, and stabilizes ventilation. In endoscopic retrograde cholangiopancreatography (ERCP) under dexmedetomidine‐based sedation, opioids are often required but increase the risk of respiratory depression and delayed recovery.
Tomotaka Mori +15 more
wiley +1 more source
When Hypercapnia Misleads: A Case of Respiratory-Onset Motor Neuron Disease. [PDF]
Kordi Y, Ismail M, Estabrook E.
europepmc +1 more source

