Results 121 to 130 of about 120,195 (312)

How well can familial hypercholesterolemia be identified in an electronic health record database? [PDF]

, 2018
Katherine E Mues,1 Alina N Bogdanov,2 Keri L Monda,1 Larisa Yedigarova,3 Alexander Liede,1 Lee Kallenbach2 1Center for Observational Research, Amgen Inc., Thousand Oaks, CA, USA; 2Practice Fusion, San Francisco, CA, USA; 3US Medical Affairs, Amgen ...
Yedigarova L, Monda KL, Kallenbach L, Mues KE, Liede A, Bogdanov AN   +5 more
core  

Adaptive Pudendal Nerve Stimulation: A Pilot Study on Safety, Technical Feasibility, and Clinical Effect

Neurourology and Urodynamics, EarlyView.
ABSTRACT Purpose To evaluate the safety, procedural feasibility, and pilot clinical outcomes for a new implanted device delivering adaptive pudendal nerve stimulation. Materials and Methods Thirteen adult women with treatment‐refractory mixed (n = 8) or urge (n = 5) urinary incontinence were implanted with a Picostim‐DyNeuMo system incorporating an ...
Siemen Herroelen, Charles H. Knowles, Sean Doherty, Mo Benjaber, Jacob Kerr, Karen Wendt, Aidan Crawley, Tim Denison, Stefan De Wachter   +8 more
wiley   +1 more source

Utilidad de la ecografía de alta resolución en la valoración de la aterosclerosis preclínica, riesgo cardiovascular y diagnóstico de la hipercolesterolemia familiar [PDF]

, 2006
[spa] La presente tesis valora la utilidad de la ecografía carotídea de alta resolución, como técnica diagnóstica incruenta, útil, validada, reproducible y de bajo coste que nos permite:1.
Junyent Priu, Mireia
core  

CHOLESTEROL ASSIMILATION OF Lactobacillus plantarum L8 AND Lactobacillus pentosus S1 THROUGH IN-VITRO CHOLESTEROL LOWERING ACTIVITY.

Journal of Academia, 2022
Probiotics gives a new insight in treating hypercholesterolemia. Recent research found that probiotics such as Lactobacillus possess multiple health benefits including cholesterol assimilation in human body.
Athifah Ismail , Ilyanie Hj Yaacob , Ida Muryany Md Yasin   +2 more
doaj  

Familial Hypercholesterolemia

Heart Views, 2021
openaire   +3 more sources

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Optical mapping reveals a higher level of large‐scale structural variants in a family with paternally transmitted myotonic dystrophy and independent Parkinson's disease

The Journal of Pathology, EarlyView.
Abstract Myotonic dystrophy type 1 (DM1) is a clinically challenging multisystem neuromuscular hereditary disorder, with generational increase in severity and earlier age at onset. It is caused by an unstable cytosine‐thymine‐guanine repeat expansion at the DMPK locus, accompanied by associated genetic and epigenetic modifications.
Md Mehedi Hasan, Jenna Craddock, Tingting Gong, Ruth J Lyons, Igor Stevanovski, Sanjog R Chintalaphani, Ira W Deveson, Weerachai Jaratlerdsiri, Kishore R Kumar, Vanessa M Hayes   +9 more
wiley   +1 more source

Accelerating virtual patient generation with a Bayesian optimization and machine learning surrogate model

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 486-494, March 2025.
Abstract The pharmaceutical industry has increasingly adopted model‐informed drug discovery and development (MID3) to enhance productivity in drug discovery and development. Quantitative systems pharmacology (QSP), which integrates drug action mechanisms and disease complexities to predict clinical endpoints and biomarkers is central to MID3.
Hiroaki Iwata, Ryuta Saito
wiley   +1 more source

Patient lifestyle changes for hypercholesterolemia [PDF]

, 2015
Bakalaura darba tēma – “Pacienta dzīvesveida izmaiņas hiperholesterinēmijas gadījumā”. Paaugstināts holesterīna līmenis jeb hiperholesterinēmija ir viens no galvenajiem cēloņiem saslimšanā ar sirds asinsvadu slimībām un insultu.
Sančeza, Elizabete
core  

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source