Results 101 to 110 of about 128,840 (306)

Hypercholesterolemia Promotes an Osteoporotic Phenotype [PDF]

, 2012
A role for hypercholesterolemia in the development of osteoporosis has been suggested in published reports. However, few studies contain direct evidence of a role for maintenance of cholesterol homeostasis in bone health.
Goldstein, Steven A., Solomon, Keith R., Pelton, Kristine, Krieder, Jaclynn, Freeman, Michael R., Joiner, Danese   +5 more
core   +1 more source

A multicenter, controlled, randomized trial of home‐applied dual‐light photodynamic therapy in stage I to III periodontitis (LumoNorth2022 study)

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis is a widespread, chronic infection‐triggered inflammatory condition in which professional supportive periodontal care (SPC) and daily oral hygiene form the backbone to reduce the disease activity. Light‐based treatments have shown promising antibacterial effects, but their potential for routine home use has not been ...
Paula Tegelberg, Meeri Ojala, Merja Ylipalosaari, Jori Lindroth, Anna Maria Heikkinen, Hanna Lähteenmäki, Saila Pakarinen, Ismo T. Räisänen, Timo Sorsa, Tommi Pätilä   +9 more
wiley   +1 more source

What is precision public health and where does FH fit in? [PDF]

Presentation at the FH Summit October 21, 2019, theme: familial hypercholesterolemia as a prototype for precision public health.Khoury-FHsummit-2019_508 ...

core  

Severity of periodontitis and risk of ischemic stroke: A systematic review and meta‐analysis

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis is a prevalent chronic inflammatory disease with a systemic inflammatory burden and is implicated with vascular pathology. This systematic review and meta‐analysis evaluates the association between varying severities of periodontitis and ischemic stroke with various diagnostic criteria.
Steven Sitt, Chloe J. Chang, Chin‐Wei Wang   +2 more
wiley   +1 more source

Familial Hypercholesterolemia in Pediatric Patients

, 2020
Familial hypercholesterolemia is one of the most common severe genetic conditions in the pediatric population. When left untreated, familial hypercholesterolemia could lead to cardiovascular events and, in some cases, death. This article will explore the
Ichull, Joseph A, Jr
core   +1 more source

The genetic basis of familial hypercholesterolemia: inheritance, linkage, and mutations

, 2010
Isabel De Castro-Orós1, Miguel Pocoví2, Fernando Civeira11Lipid Unit and Laboratorio de Investigación Molecular, Hospital Universitario Miguel Servet, Instituto Aragonés de Ciencias de la Salud (I+CS), Zaragoza,
Fernando Civeira, Miguel Pocoví, Isabel De Castro-Orós   +2 more
core  

The safe and effective use of tofacitinib and ustekinumab combination therapy in infantile onset inflammatory bowel disease

JPGN Reports, EarlyView.
Abstract Infantile‐onset inflammatory bowel disease (IOIBD) is a rare and severe subset of very‐early‐onset IBD, often associated with immune dysregulation and poor response to conventional therapies. Data regarding the use of Janus kinase inhibitors (JAKI) in this population is limited.
Smridhi Mahajan, Christian Wysocki, Bhaskar Gurram   +2 more
wiley   +1 more source

IMM-H007 promotes hepatic cholesterol and triglyceride metabolism by activating AMPKα to attenuate hypercholesterolemia

Acta Pharmaceutica Sinica B
Hypercholesterolemia is a significant risk factor for the development of atherosclerosis. 2′,3′,5′-Tri-O-acetyl-N6-(3-hydroxyphenyl) adenosine (IMM-H007), a novel AMPK agonist, has shown protective effects in metabolic diseases.
Jiaqi Li, Mingchao Wang, Kai Qu, Yuyao Sun, Zequn Yin, Na Dong, Xin Sun, Yitong Xu, Liang Chen, Shuang Zhang, Xunde Xian, Suowen Xu, Likun Ma, Yajun Duan, Haibo Zhu   +14 more
doaj   +1 more source

Genetically confirmed familial hypercholesterolemia in outpatients with hypercholesterolemia.

Journal of geriatric cardiology : JGC, 2018
Familial hypercholesterolemia (FH) is an autosomal dominant disorder of lipoprotein metabolism which can lead to premature coronary heart disease (pCHD). There are about 3.8 million potential FH patients in China, whereas the clinical and genetic data of FH are limited.Dutch Lipid Clinic Network (DLCN) criteria was used to diagnose FH in outpatients ...
Wang, Xu, Jiang, Long, Sun, Li-Yuan, Wu, Yue, Wen, Wen-Hui, Wang, Xi-Fu, Liu, Wei, Zhou, Yu-Jie, Wang, Lu-Ya   +8 more
openaire   +2 more sources

The effects of royal jelly on human health: A narrative review of clinical studies

JSFA reports, EarlyView.
Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Georgios Goras, Andreas Thrasyvoulou, Evanthia Tsilimpokou   +2 more
wiley   +1 more source