Results 131 to 140 of about 180,738 (304)

Global scientific trends in hypercholesterolemia research from 2003 to 2023: a data-driven bibliometric and visual analysis

Frontiers in Cardiovascular Medicine
BackgroundCardiovascular disease remains the leading cause of mortality and disability worldwide. Hypercholesterolemia is a significant causal factor of ischemic heart disease, contributing to half of all cardiovascular fatalities.MethodsThis study ...
Haoxin Guo, Haoxin Guo, Qihui Wang, Qihui Wang, Yinling Wang, Yinling Wang, Xiaolong Dong, Xiaolong Dong, Zhongqing Wang, Hui Kang, Hui Kang, Shitong Cheng, Shitong Cheng   +12 more
doaj   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Familial hypercholesterolemia

Clinica Chimica Acta, 1971
Kehayoglou, K.A., Karli, N.J., Kiriazidis, K.J., Theodossiou, A.   +3 more
openaire   +3 more sources

Comprehensive Evidence for Mortality and Underlying Morbidity Related to Visceral Fat Distribution

Med Research, EarlyView.
ABSTRACT Linking obesity to mortality is an intriguing and controversial topic. This study tried to comprehensively assess 8 adiposity surrogates and mortality association among middle‐to‐old‐aged adults to identify a superior one, and explore explanatory disorders. Data sources included the National Health and Nutrition Examination Survey (NHANES), UK
Haolong Zhou, Danyang Ling, Qin Huang, Jiaojun Liang, Guanhua Su, Zhangbo Cui, Ziwei Chen, Xiaowen Ma, Zhou Jiang, Shuo Zheng, Haodong Tian, Qi Wang   +11 more
wiley   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Simultaneous Cerebral Blood Flow and Cerebrovascular Reactivity Obtained From Novel Multi‐Band Multi‐Echo Pseudo‐Continuous Arterial Spin Labeling (M2‐PCASL) Sequence: A Test–Retest Reliability Study

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose We aim to assess the reliability of cerebral blood flow (CBF) and cerebrovascular reactivity (CVR) obtained simultaneously from a novel multi‐band pseudo‐continuous arterial spin labeling (M2‐PCASL) sequence and hypercapnic gas challenge, to examine factors influencing CBF variability, and to evaluate the impact of carbon dioxide (CO2)
Jody Todd, Maria‐Julieta Mateos, Ibraheem Budeir, Deqiang Qiu   +3 more
wiley   +1 more source

Familial Hypercholesterolemia

Journal of Atherosclerosis and Thrombosis, 2014
Tamio, Teramoto, Jun, Sasaki, Shun, Ishibashi, Sadatoshi, Birou, Hiroyuki, Daida, Seitaro, Dohi, Genshi, Egusa, Takafumi, Hiro, Kazuhiko, Hirobe, Mami, Iida, Shinji, Kihara, Makoto, Kinoshita, Chizuko, Maruyama, Takao, Ohta, Tomonori, Okamura, Shizuya, Yamashita, Masayuki, Yokode, Koutaro, Yokote, Mariko, Harada-Shiba, Hidenori, Arai, Hideaki, Bujo, Atsushi, Nohara, Takao, Ohta, Shinichi, Oikawa, Tomoo, Okada, Akihiko, Wakatsuki   +25 more
openaire   +3 more sources

Chronic Disease and Disability in an 18th‐Century Portuguese Nun: An Integrative Multisource Approach

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT This study presents an integrative approach to chronic disease and disability in a Portuguese nun who died in 1779. The aim is to interpret her condition by combining osteopathological and burial context evidence with written sources. It offers a concise example of how bringing these sources together can enhance pathological interpretation and
Nathalie Antunes‐Ferreira
wiley   +1 more source

Computational Evaluation of Statin Analogs Targeting HMG‐CoA Reductase for Coronary Artery Disease Treatment

ChemistryOpen, EarlyView.
Molecular dynamics analysis of novel statin analogs shows that binding induces superior stabilization of HMG‐CoA reductase. As shown by the solvent‐accessible surface area profile, ligand‐induced rigidity offers a new, effective strategy for drug design. Cardiovascular diseases remain a leading cause of global mortality.
Yoshua B. Mtulo, Geradius Deogratias, James E. Mgaya, Andrew S. Paluch, Lucas Paul   +4 more
wiley   +1 more source

The Dynamic Evolution of Lipid Profiles Following Transjugular Intrahepatic Portosystemic Shunt in Patients With Liver Cirrhosis

Portal Hypertension &Cirrhosis, EarlyView.
Cirrhosis is frequently accompanied by varying degrees of lipid profile abnormalities. This study confirms that these profiles are differentially affected by disease etiology and progressively worsen—with significant reductions in TC, HDL‐C, and LDL‐C—as liver disease severity increases. TIPS improves lipid profiles, particularly by increasing HDL‐C in
Jiamin Xu, Qinnian Li, Lagan Kumar Manandhar, Bilian Zhu, Chenrui Zhang, Weimin Bao, Yingmei Tang   +6 more
wiley   +1 more source