Results 161 to 170 of about 119,690 (213)

Hypercholesterolemia and angiogenesis

The American Journal of Cardiology, 1993
Hypercholesterolemia is associated with endothelial cell dysfunction, which may be partly related to an accumulation of toxic lipoprotein degradation products in artery walls. Oxidized low-density lipoprotein and its products have been incriminated in the impairment of transmembrane signaling, a process that may alter the responsiveness of endothelial ...
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Hypercholesterolemia and dyslipidemia

Current Treatment Options in Cardiovascular Medicine, 2000
Disorders of cholesterol and lipoprotein metabolism are at the heart of atherosclerosis and coronary artery disease (CAD). CAD, however, is a metabolic disorder that involves a complex interaction between genetic susceptibility and environmental conditions.
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Hypercholesterolemia and Platelets

1978
Many lines of evidence have linked the circulating plasma lipoproteins with thrombosis, and both with atherosclerosis. Many theories of atherogenesis include mural thrombosis as one of the inciting factors, or the sole inciting factor, for atherosclerotic plaque formation.
R S, Lees, A C, Carvalho
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Lovastatin for Hypercholesterolemia

Drug Intelligence & Clinical Pharmacy, 1988
Lovastatin is the first 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor approved for the treatment of primary hypercholesterolemia. It is indicated as adjunctive therapy to dietary control and should be initiated at 20 mg/d in the evening. With higher dosages, twice-daily dosing is preferred, particularly when the dosage reaches the
F P, Zeller, K C, Uvodich
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Guggul for hypercholesterolemia

American Journal of Health-System Pharmacy, 2005
The mukul myrrh tree ( Commiphora mukul ), a native of India, secretes the substance guggul (also known as guggulu or guggulipid) when its bark is injured. Guggul has been used in Ayurvedic medicine for thousands of years to treat arthritis and obesity.
Kelly M, Shields, Michael P, Moranville
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Treatment of Hypercholesterolemia

Medical Clinics of North America, 1982
After discussing the indications for treatment of familial hypercholesterolemia and the importance of a differential diagnosis, the authors describe drug therapy for the disorder with special attention to combined drug regimens. The surgical treatment of hypercholesterolemia and the treatment of homozygous and other forms of hypercholesterolemia are ...
J P, Kane, M J, Malloy
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Familial hypercholesterolemia

Current Treatment Options in Cardiovascular Medicine, 2002
Heterozygous familial hypercholesterolemia is a common, severe form of elevated plasma, low-density lipoprotein (LDL) cholesterol. Familial hypercholesterolemia is under-recognized and under-treated despite well-known benefits from available lipid-lowering medications.
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Therapy for Hypercholesterolemia

Primary Care: Clinics in Office Practice, 1990
For most patients, hypercholesterolemia can be effectively lowered with drug therapy but only after several issues have been considered. First, drug therapy should never be considered without adequate dietary intervention. Dietary therapy may be effective for many patients with mild to moderate elevations in cholesterol. None of the drugs used to treat
B L, Carter, F R, Bakht
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Hyperinsulinemia in patients with hypercholesterolemia

Journal of Clinical Endocrinology & Metabolism, 1992
An independent association between hypercholesterolemia and high insulin levels has not consistently emerged from large-scale epidemiologic observations. We selected 39 patients with elevated low-density (LDL) cholesterol levels but normal body weight, blood pressure, and glucose tolerance, and compared them to 36 normocholesterolemic, healthy control ...
PAOLISSO, Giuseppe, Ferrannini E, Sgambato S, Varricchio M, D'Onofrio F.   +4 more
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MANAGEMENT OF HYPERCHOLESTEROLEMIA

Cardiology Clinics, 2000
Benefit from the treatment of hyperlipidemia has now been conclusively documented, and this article has focused on the clinical trial data supporting diet and drug therapy in adult patients with different lipoprotein disorders and discussed therapeutic approaches with a focus on reducing plasma concentrations of LDL cholesterol. National guidelines for
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