Addiction, Volume 121, Issue 10, Page 2682-2690, October 2026.Abstract Background and aims Increased risk of alcohol dependence is recognised following bariatric surgery. Modified gastrointestinal anatomy and neurohormonal profiles lead to altered alcohol metabolism, peak blood alcohol concentrations and enhanced reward circuits and cravings.
Thomas J. Williams +4 more
wiley +1 more source
Genetic yield of next-generation sequencing for detecting monogenic familial hypercholesterolemia in uzbek patients with coronary artery disease. [PDF]
PLoS OneAlieva RB +10 more
europepmc +1 more source
Pubertal Timing Associates With Cardiometabolic Markers During Puberty and in Young Adulthood
Acta Paediatrica, Volume 115, Issue 10, Page 2168-2190, October 2026.ABSTRACT Aim To study how pubertal timing associates with cardiometabolic measures in puberty and young adulthood. Methods Cardiovascular risk factors, anthropometry and pubertal development were regularly studied in STRIP study subjects until age 26 years.
Saga Nummela +7 more
wiley +1 more source
"RAL" the LDLR to lysosomes for degradation. [PDF]
Life MetabGuan Y, Huang Y, Li Z, Wang Y.
europepmc +1 more source
The Crosstalk Between Diabetes and Alzheimer's Disease: A Molecular Perspective
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.Increasing evidence indicates an association between type 2 diabetes mellitus and Alzheimer’s disease, contributing to the proposed concept of AD as “type 3 diabetes.” Shared biological features such as impaired insulin signaling, chronic inflammation, mitochondrial dysfunction, and oxidative stress have been observed in both T2DM and AD.
Deniz Catakli +3 more
wiley +1 more source
Clinical Genetics, Volume 110, Issue 4, Page 502-507, October 2026.This study illustrates the phenotypic variability of LZTR1‐related Noonan syndrome type 10 in two pediatric patients, including presentations without congenital heart defects. The findings emphasize the importance of whole‐exome sequencing and longitudinal re‐evaluation of variants of uncertain significance in achieving accurate diagnosis.
Karolina Skrzyńska +3 more
wiley +1 more source
Serum Folate in Relation to Lipid Abnormalities in Community-Dwelling Adults: A Population-Based Cross-Sectional Study in Zhejiang Province, China. [PDF]
NutrientsChen X +5 more
europepmc +1 more source
Weight Loss Outcomes of Routine Dietetic Treatment in Primary Care
Clinical Obesity, Volume 16, Issue 5, October 2026.Clinically relevant weight loss (≥ 5%) is a key treatment goal in dietetic care for patients with overweight or obesity. Although clinical trials are usually highly effective in reaching this treatment goal, little is known about success rates during routine dietetic treatment, the typical timing of reaching this treatment goal, and how long it is ...
Annemieke van de Riet +5 more
wiley +1 more source
Lifestyle and Cardiovascular Risk Factors by Educational Attainment in a Mediterranean Setting: A Cross-Sectional Analysis of a Population-Based Sample. [PDF]
Glob HeartÁlamo-Junquera D +7 more
europepmc +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8925-8935, October 2026.ABSTRACT Aims To assess whether self‐reported leisure‐time physical activity, moderate‐to‐vigorous leisure‐time physical activity, and genetically determined cardiorespiratory fitness are associated with age‐related BMI trajectories and incident obesity. Methods We pooled 14 993 adults (30–90 years; 52.7% women; cohorts: REGICOR‐ACRISC, ILERVAS, ARTPER)
Javier Hernando‐Redondo +13 more
wiley +1 more source