Results 221 to 230 of about 128,840 (306)

Selective IL‐23 Inhibition in Conventional Treatment‐Refractory Pyoderma Gangrenosum: A Multicenter, Retrospective Study

open access: yesInternational Journal of Dermatology, Volume 65, Issue 10, Page 2055-2065, October 2026.
The clinical effects of selective IL‐23 inhibition in refractory pyoderma gangrenosum, highlighting progressive ulcer healing, reduction in inflammation and pain, and steroid‐sparing effect, supporting the role of the IL‐23/Th17 axis as a therapeutic target.
Luca Bettolini   +25 more
wiley   +1 more source

Genomic Medicine Sweden: Advancing precision medicine at the national level

open access: yesJournal of Internal Medicine, Volume 300, Issue 4, Page 397-419, October 2026.
Abstract High‐throughput sequencing has transformed clinical diagnostics of rare diseases (RD), cancer and infectious diseases by enabling the identification of disease‐causing genetic alterations and facilitating individualised treatment and care.
Anders Edsjö   +58 more
wiley   +1 more source

[Hypercholesterolemia and atherosclerosis].

open access: yesNihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1993
openaire   +2 more sources

Efficacy of 0.5% Tretinoin in the Treatment of Equine Aural Plaques

open access: yesVeterinary Dermatology, Volume 37, Issue 5, Page 664-671, October 2026.
Background: Equine aural plaques are a benign form of auricular papillomatosis caused by equine papillomavirus. Despite the efficacy of 5% imiquimod cream, a marked local reaction is frequently observed during therapy, often requiring sedation before application.
Felipe Sperandio de Mattos   +14 more
wiley   +1 more source

Urinary metabolic age from high-resolution nuclear magnetic resonance spectroscopy reveals longitudinal aging patterns. [PDF]

open access: yesJ Gerontol A Biol Sci Med Sci
Gauß KF   +7 more
europepmc   +1 more source

Metabolic Shifts Precede Cognitive Decline in the Male hAß‐KI Alzheimer's Mouse Model

open access: yesThe FASEB Journal, Volume 40, Issue 17, 15 September 2026.
A major barrier in Alzheimer's disease (AD) research is the lack of animals that recapitulate sporadic AD. The humanized amyloid‐beta knock‐in mice (hAß‐KI) exhibit age‐dependent cognitive decline and beta‐amyloid accumulation. However, limited research has been conducted related to AD risk factors and sex‐specific responses.
Evelin Melekh   +8 more
wiley   +1 more source

Next‐Generation Manufacturing: The Evolving Role of Biocatalysis in AstraZeneca

open access: yesChemBioChem, Volume 27, Issue 17, 14 September 2026.
Biocatalysis is strengthening AstraZeneca's manufacture of active pharmaceutical ingredients through faster development, robust scale‐up, and lower environmental impact. Case studies illustrate where biocatalysis delivers greatest value, while enabling platforms, teams, and partnerships shape its next phase.
Alba Diaz‐Rodriguez   +4 more
wiley   +1 more source

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