Results 31 to 40 of about 2,437,081 (240)

Allergy and the Heart

JACC: Case Reports, 2020
A 40-year-old woman with history of atopy and peripheral eosinophilia presented with clinical signs of heart failure. Echocardiography revealed a restrictive cardiomyopathy with biventricular thrombi.
Cullen E. Buchanan, MD, Ekta Kakkar, MD, Stephen C. Dreskin, MD, PhD, Larry A. Allen, MD, MHS, Daniel W. Groves, MD, Natasha L. Altman, MD   +5 more
doaj   +1 more source

FIP1L1-PDGFRA-Associated Hypereosinophilic Syndrome as a Treatable Cause of Watershed Infarction

Stroke, 2021
Supplemental Digital Content is available in the text. Background and Purpose: Ischemic stroke has been reported in various conditions associated with eosinophilia.
Juliette Tennenbaum, M. Groh, L. Venditti, F. Campos-Gazeau, Emilie Chalayer, T. de Broucker, M. Hamidou, M. Hunault, A. Lyoubi, Raphael Meunier, T. Muron, D. Sène, B. Slama, C. Guidoux, G. Lefèvre, J. Kahn, C. Denier, J. Rohmer   +17 more
semanticscholar   +1 more source

Imatinib-induced interstitial pneumonitis – a literature review and case report [PDF]

, 2020
Imatinib is generally well tolerated, with mild common side effects such as nausea and vomiting, diarrhea, muscle cramps, fatigue, skin rash and edema; however, pulmonary complications are uncommon. A 73-year-old woman undergoing one month treatment with
Ciulei, George, Coste, Sorina Cezara, Cozma, Angela, Fabian, Ovidiu, Minciuna, Iulia, Muresan, Flaviu, Negrean, Vasile, Orasan, Olga Hilda, Para, Ioana, Sitar-Taut, Adela, Stefan, Andreea Maria, Tarmure, Simina, Urian, Laura   +12 more
core   +2 more sources

The increasing incidence and prevalence of hypereosinophilic syndrome in the United Kingdom

Immunity, Inflammation and Disease, 2021
Data on the burden of hypereosinophilic syndrome (HES) are limited. This study investigated the incidence and prevalence of HES using real‐world data from patients in the United Kingdom.
G. Requena, J. Logie, Daniel C Gibbons, J. Steinfeld, M. V. Van Dyke   +4 more
semanticscholar   +1 more source

Idiopathic hypereosinophilic syndrome presenting with recalcitrant oral and genital ulcers responding well to thalidomide

Indian Dermatology Online Journal, 2023
Hypereosinophilic syndrome is a myeloproliferative disorder characterized by abnormal accumulation of eosinophils in the blood or peripheral tissues. It is uncommonly seen in children.
Sahana M Srinivas, Pooja G Chebbi, Sanjay K Shivappa   +2 more
doaj   +1 more source

Efficacy and safety of mepolizumab in hypereosinophilic syndrome: A phase III, randomized, placebo-controlled trial

Journal of Allergy and Clinical Immunology, 2020
Background: Anti–IL-5 therapy is a potential treatment for patients with hypereosinophilic syndrome (HES), although its clinical efficacy is unclear. Objective: We sought to investigate the clinical efficacy and safety of mepolizumab versus placebo in ...
F. Roufosse, J. Kahn, M. Rothenberg, A. Wardlaw, A. Klion, S. Y. Kirby, M. Gilson, J. Bentley, E. Bradford, S. Yancey, J. Steinfeld, G. Gleich   +11 more
semanticscholar   +1 more source

Hypereosinophilic syndrome: considerations for the cardiologist

Heart, 2021
Eosinophil-mediated endomyocardial damage is a well-known complication in patients with hypereosinophilic syndromes (HES). Although management and survival have improved significantly, some patients continue to develop severe cardiomyopathy as a direct ...
A. Bondue, C. Carpentier, F. Roufosse
semanticscholar   +1 more source

Hypereosinophilic syndrome

The Indian Journal of Pediatrics, 2006
Hypereosinophilic syndrome is a leukoproliferative disease characterised by sustained overproduction of eosinophils. The three diagnostic criteria for this disorder are (1) Eosinophilia of greater than 1500 cells/ml, persisting for longer than 6 months, (2) lack of another diagnosis to explain the eosinophilia and (3) signs and symptoms of organ ...
C, Venkatesh, E, Mahender, S, Janani, S, Malathi, M, Vijayakumar, B R, Nammalwar   +5 more
  +7 more sources

Association of Thrombosis With Hypereosinophilic Syndrome in Patients With Genetic Alterations

JAMA Network Open, 2021
Key Points Question What are the incidence of and risk factors associated with thrombotic events in patients with hypereosinophilic syndromes? Findings In this cohort study that included 71 adults with hypereosinophilic syndrome, thrombotic events were ...
O. Leiva, O. Baker, Andrew Jenkins, A. Brunner, H. Al-Samkari, R. Leaf, R. Rosovsky, A. Fathi, James I Weitzman, L. Bornikova, V. Nardi, G. Hobbs   +11 more
semanticscholar   +1 more source

Idiopathic Hypereosinophilic Syndrome. A Clinical Case

Архивъ внутренней медицины, 2022
Idiopathic hypereosinophilic syndrome is a rare phenomenon in medical practice. The main criterion for diagnosis is a persistent increase in the level of eosinophils above 1.5 * 109/ l in the blood serum and the absence of clinical and laboratory and ...
E. A. Lopina, A. G. Dushina, R. A. Libis
doaj   +1 more source