Results 31 to 40 of about 10,507 (195)

Liver eosinophilic infiltrate is a significant finding in patients with chronic hepatitis C. [PDF]

, 2008
Eosinophilic infiltrate of liver tissue is described in primary cholestatic diseases, hepatic allograft rejection and drug-induced liver injury, but its significance and its implications in chronic hepatitis C are unknown.
ALESSI, N, CABIBI, Daniela, CAMMA', Calogero, CRAXI, Antonio, DI MARCO, Vito, DONATELLI, Maria, PETTA, Salvatore, TARANTINO, Giuseppe   +7 more
core   +1 more source

Acute kidney injury secondary to thrombotic microangiopathy associated with idiopathic hypereosinophilic syndrome: a case report and review of the literature

Journal of Medical Case Reports, 2019
Background Renal involvement in idiopathic hypereosinophilic syndrome is uncommon. The mechanism of kidney damage can be explained as occurring via two distinct pathways: (1) thromboembolic ischemic changes secondary to endocardial disruption mediated by
Diana Curras-Martin, Swapnil Patel, Huzaif Qaisar, Sushil K. Mehandru, Avais Masud, Mohammad A. Hossain, Gurpreet S. Lamba, Harry Dounis, Michael Levitt, Arif Asif   +9 more
doaj   +1 more source

Eosinophilia characterized by a rare CCT6B mutation and responsive to tyrosine kinase inhibition: Case report and literature review

Leukemia Research Reports, 2021
Hypereosinophilic syndrome is a rare disorder arising from neoplastic, or idiopathic causes. The availability of NGS panels has increasingly identified rare mutations as underlying pathogenic events and have led to reclassification of cases of idiopathic
Abhay Singh, Jeffrey Baron, Namrata Singh, Gopisree Peringeth, Eunice S. Wang   +4 more
doaj   +1 more source

Wells Syndrome with Multiorgan Involvement Mimicking Hypereosinophilic Syndrome

Case Reports in Dermatology, 2009
Eosinophil-associated diseases represent a spectrum of heterogeneous disorders, where blood and cutaneous eosinophilia is the most important feature and eosinophils are the principal cause of cutaneous lesions.
M. Carlesimo, L. Fidanza, E. Mari, G. Feliziani, A. Narcisi, G. De Marco, A. Bartolazzi, G. Camplone   +7 more
doaj   +1 more source

Idiopathic hypereosinophilic syndrome: A rare diagnosis in children

Clinical Case Reports, 2020
Idiopathic hypereosinophilic syndrome (IHES) is one of numerous hypereosinophilic syndromes. The incidence of IHES among children is unknown, but it is considered a rare disease.
Kristine Appel Uldall Pallesen, Troels Herlin, Mette Holm, Christian Høst, Mette Christiansen, Mette Ramsing, Mads Kirchheiner Rasmussen, Mette Sommerlund   +7 more
doaj   +1 more source

Hypereosinophilic Syndrome Leading to Severe Right-Sided Heart Failure in a Patient with Ebstein's Anomaly

Case Reports in Cardiology, 2013
A 36-year-old male with mild Ebstein's anomaly developed severe right-sided heart failure, following a 5-year-long course of hypereosinophilic syndrome. No regular followups had been done, during the years of antineoplastic therapy.
Joas John Kyabonaki, Bjarne Linde Nørgaard, Søren Høyer, Niels Holmark Andersen   +3 more
doaj   +1 more source

Hypereosinophilic Syndrome: What to Expect in Echo

Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2020
Hypereosinophilic syndrome is characterized by eosinophilic tissue damage. The clinical presentation is variable. When there is cardiac involvement, which occurs in 40%–60% of cases, it is referred commonly as Loeffler's endocarditis.
Ashok Garg, Deepak Agrawal, G. L. Sharma
doaj   +1 more source

Hypereosinophilia causes progressive cardiac pathologies in mice

iScience, 2023
Summary: Hypereosinophilic syndrome is a progressive disease with extensive eosinophilia that results in organ damage. Cardiac pathologies are the main reason for its high mortality rate.
Nicola Laura Diny, Megan Kay Wood, Taejoon Won, Monica Vladut Talor, Clarisse Lukban, Djahida Bedja, Nadan Wang, Hannah Kalinoski, Abdel Daoud, C. Conover Talbot, Jr., Brian Leei Lin, Daniela Čiháková   +11 more
doaj   +1 more source

Eosinofiilsed kopsuhaigused [PDF]

, 2012
Eosinofiilsete kopsuhaiguste (EK) puhul on peamiseks koekahjustust põhjustavaks rakuliigiks eosinofiilid, mis kogunevad kopsude interstiitsiumi ja hingamisteedesse.
Altraja, Alan, Makke, Vahur, Püttsepp, Enn   +2 more
core   +2 more sources

Activation of tyrosine kinases by mutation of the gatekeeper threonine. [PDF]

, 2008
Protein kinases targeted by small-molecule inhibitors develop resistance through mutation of the gatekeeper threonine residue of the active site. Here we show that the gatekeeper mutation in the cellular forms of c-ABL, c-SRC, platelet-derived growth ...
Azam, Mohammad, Daley, George, Gray, Nathanael, KURIYAN, John, Seeliger, Markus   +4 more
core   +1 more source