Results 41 to 50 of about 7,879 (209)

Hypereosinophilia–An Unusual Cause of Multiple Embolic Strokes and Multi-Organ Dysfunction [PDF]

Journal of Clinical and Diagnostic Research, 2013
‘Eosinophilia’ can occur due to a large number of allergic, infectious, neoplastic, and idiopathic diseases. It can range in severity from a self-limiting condition to a life-threatening disorder. The term ‘hypereosinophilia’ refers to eosinophil levels
Geeta A. Khwaja, Ashish Duggal, Amit Kulkarni, Neera Choudhary, Meena Gupta, Debashish Chowdhury, Vikram Bohra, Dhruv Zutshi   +7 more
doaj   +1 more source

Recalcitrant course of bullous pemphigoid indicating coexisting hypereosinophilic syndrome: A case report and literature review

Clinical Case Reports, 2023
Key Clinical Message As dermatologists, we must be aware that even limited localized lesions may signal a life‐threatening condition, for which early diagnosis and treatment can improve the prognosis. Abstract Bullous pemphigoid is an autoimmune disorder
Raziyeh Ganji, Reem Diab, Farideh Mousavi, Fahimeh Abdollahimajd   +3 more
doaj   +1 more source

Eosinophilia characterized by a rare CCT6B mutation and responsive to tyrosine kinase inhibition: Case report and literature review

Leukemia Research Reports, 2021
Hypereosinophilic syndrome is a rare disorder arising from neoplastic, or idiopathic causes. The availability of NGS panels has increasingly identified rare mutations as underlying pathogenic events and have led to reclassification of cases of idiopathic
Abhay Singh, Jeffrey Baron, Namrata Singh, Gopisree Peringeth, Eunice S. Wang   +4 more
doaj   +1 more source

Hypereosinophilic Syndrome Simulating an Acute Coronary Syndrome [PDF]

, 2015
Objectives: to report a case of hypereosinophilic syndrome which presented clinically acute coronary syndrome. Materials and methods: we describe a case of a 69-year-old woman with acute coronary syndrome and peripheral hypereosinophilia.
Neves, Clarinda, Neves, Joana, Franco, Fátima, Clarinda Neves, José Mesquita Bastos, Joana Neves, Ferreira, Raquel, Raquel Ferreira, Fátima Franco, Bastos, José Mesquita   +9 more
core   +1 more source

Acute kidney injury secondary to thrombotic microangiopathy associated with idiopathic hypereosinophilic syndrome: a case report and review of the literature

Journal of Medical Case Reports, 2019
Background Renal involvement in idiopathic hypereosinophilic syndrome is uncommon. The mechanism of kidney damage can be explained as occurring via two distinct pathways: (1) thromboembolic ischemic changes secondary to endocardial disruption mediated by
Diana Curras-Martin, Swapnil Patel, Huzaif Qaisar, Sushil K. Mehandru, Avais Masud, Mohammad A. Hossain, Gurpreet S. Lamba, Harry Dounis, Michael Levitt, Arif Asif   +9 more
doaj   +1 more source

Watershed Infarctions and Hypereosinophilic Syndrome Secondary to Metastatic Lung Cancer: A Case Report [PDF]

, 2021
Watershed infarcts are traditionally attributed to ischemia caused by hypoperfusion, with or without vessel stenosis. Implicated diseases usually include atherosclerosis, congestive heart failure, hypotension, angiitis, and less commonly ...
Tsui, Brian Q, Thomas, Mariam, Hathout, Gasser, Tsui, Brian Q ; Thomas, Mariam ; Hathout, Gasser   +3 more
core   +1 more source

Idiopathic Hypereosinophilic Syndrome Presenting With Acute Heart Failure and Mesenteric Thromboembolism: Review of the Literature*

, 2018
Acute heart failure due to cardiac involvement of idiopathic hypereosinophilic syndrome has poor prognosis and high mortality rate. We present a 52 year old male patient with hypereosinophilic syndrome resulting in acute heart failure and mesenteric ...
Demet Menekșe Gerede, Cebrail Yarlıoğlueș, İrem Müge Akbulut, Mustafa Fırat Coșkun, İrem Dinçer, Hüseyin Göksülük   +5 more
core   +1 more source

Hypereosinophilia causes progressive cardiac pathologies in mice

iScience, 2023
Summary: Hypereosinophilic syndrome is a progressive disease with extensive eosinophilia that results in organ damage. Cardiac pathologies are the main reason for its high mortality rate.
Nicola Laura Diny, Megan Kay Wood, Taejoon Won, Monica Vladut Talor, Clarisse Lukban, Djahida Bedja, Nadan Wang, Hannah Kalinoski, Abdel Daoud, C. Conover Talbot, Jr., Brian Leei Lin, Daniela Čiháková   +11 more
doaj   +1 more source

Hypereosinophilic Syndrome: Contemporary Approaches to Molecular-Genetic Diagnostics and Gene-Engineered Biologic Therapy

Медицина и биотехнологии
Introduction. In recent years, there has been a growing interest among researchers in conditions associated with hypereosinophilia and the therapeutic potential of genetically engineered biological agents.
Larisa A. Balykova, Anna V. Krasnopolskaya, Marina V. Shirmankina, Diva Augusta T. Mendes, Anastasia M. Khanina   +4 more
doaj   +1 more source

Tezepelumab for refractory eosinophilic granulomatosis with polyangiitis-related asthma

Respiratory Research
Conventional immunosuppressants are ineffective for the management of EGPA-related asthma. Tezepelumab is a human monoclonal antibody that inhibits thymic stromal lymphopoietin (TLSP) that has proven efficacy in several phase 3 studies for the treatment ...
Nina Vincent-Galtié, Quentin Marquant, Emilie Catherinot, Felix Ackermann, Antoine Magnan, Colas Tcherakian, Matthieu Groh   +6 more
doaj   +1 more source