Results 61 to 70 of about 7,879 (209)

Multiple Cerebral Infarcts and Encephalopathy as the First Clinical Manifestations of Hypereosinophilic Syndrome: A Case Report and Narrative Review

Pulse
Background: Hypereosinophilic syndrome is characterized by a peripheral blood eosinophil count >1.5 × 103/μL on two different examinations within a month of each other and/or a 20% or higher percentage of eosinophils in a bone marrow section ...
Sonia Romano, Giulia Avola, Marco Cesare Angeli, Francesca Brazzale, Elena Giacopazzi, Paola Castellini, Antonio Genovese   +6 more
doaj   +1 more source

Eosinophilic Granulomatous Polyangiitis Presenting With Finger Swelling as the Main Manifestation: A Case Report and Analysis

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT EGPA should be considered in elderly patients with asthma presenting with unexplained finger swelling and eosinophilia. Early recognition prevents delayed diagnosis.
Lingfang Zhou
wiley   +1 more source

Ruxolitinib found to cause eyelash growth: a case report

Journal of Medical Case Reports, 2017
Background Hypereosinophilic syndrome is a hematologic disorder in which the eosinophils proliferate. Oral Janus kinase inhibitors are known to be effective treating hypereosinophilic syndrome.
Julia Song, Alice Song, Trisa Palmares, Michael Song, Harold Song   +4 more
doaj   +1 more source

Successful Management of Septic Splenitis in an Abyssinian Cat

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
A 3.5‐year‐old female neutered Abyssinian with pyrexia of unknown origin and splenomegaly was diagnosed with septic splenitis. Complete resolution of clinical signs followed splenectomy and antibiotic treatment with pradofloxacin. Septic splenitis, although uncommon, should be considered as a differential diagnosis in patients with splenomegaly and ...
Martina Vecín Sancho, Perrine Henry, Mica Taylor, Catherine Davidson, María Lázaro Muñoz, Efa Llewellyn, Maša Vilfan, Paola Cazzini, Linda Morrison, Kelly Blacklock, Danièlle Gunn‐Moore   +10 more
wiley   +1 more source

Wells syndrome: clinical findings and treatment management in a large cohort of 48 patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 5, Page 644-656, May 2026.
Summary Background and Objectives: Wells syndrome (WS) is a rare inflammatory skin disorder typically characterized by erythematous, edematous, and pruritic plaques. Despite its distinct histopathological features, WS remains an underdiagnosed disease due to its variable clinical presentations and overlap with other dermatological conditions.
Marco Adriano Chessa, Silvia Robuffo, Tullio Brunetti, Luca Rapparini, Bianca Maria Piraccini, Cosimo Misciali, Beatrice Raone, Iria Neri, Federica Filippi   +8 more
wiley   +1 more source

Association of Eosinophil Counts and Ratios With Clinical Outcomes After Acute Ischemic Stroke

Brain and Behavior, Volume 16, Issue 4, April 2026.
This study demonstrates for the first time that low peripheral eosinophil levels are independent predictors of adverse 5‐year outcomes in ischemic stroke or TIA patients, providing a novel basis for risk stratification and future mechanistic research.
Yangying Lu, Lei Zhang, Hongyi Yan, Yuesong Pan, Jing Jing, Xia Meng, Xingquan Zhao, Liping Liu, Yilong Wang, Yongjun Wang, Honglian Wang, Wenchao Li, Bihong Zhu   +12 more
wiley   +1 more source

Steroid‐Free Remission of Eosinophilic Granulomatosis With Polyangiitis Achieved With Low‐Dose Mepolizumab: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
Successful steroid‐free remission of MPO‐ANCA‐negative eosinophilic granulomatosis with polyangiitis (EGPA). Due to concurrent poorly controlled diabetes, standard high‐dose glucocorticoids were avoided. Low‐dose mepolizumab (100 mg/month) monotherapy was initiated, resulting in rapid eosinophil reduction, resolution of pulmonary infiltrates, and ...
Suzuka Matsuoka, Yuki Takigawa, Jun Nishimura, Hiromi Watanabe, Kenichiro Kudo, Ken Sato, Keiichi Fujiwara, Takuo Shibayama   +7 more
wiley   +1 more source

SUCCESSFUL LONG-TERM CONTROL OF IDIOPATHIC HYPEREOSINOPHILIC SYNDROME WITH ETOPOSIDE

, 1991
A 38-year-old man with idiopathic hypereosinophilic syndrome had an inadequate response to steroids and severe side effects from hydroxyurea treatment, which necessitated withdrawal of the treatment. Successful control of clinical symptoms and eosinophil
SMIT, AJ, DEVRIES, EGE, DEVRIES, EGE; id_orcid, VANESSEN, LH   +3 more
core   +2 more sources

A novel JAK1 variant in chronic eosinophilic leukaemia with response to benralizumab

British Journal of Haematology, EarlyView.
Isabel C. Vallecillo‐Viejo, Michael D. Claiborne, Charles F. Anderson, Samantha Shafer, Alan Saven, Bryce A. Seifert, Morgan Similuk, Magdalena Walkiewicz, Irina Maric, Pia R. Crespo, Lori Broderick, Andrew A. White, Amy D. Klion   +12 more
wiley   +1 more source

Straight to Phase III: Model‐Informed Approach Speeds Depemokimab Clinical Development in Interleukin‐5‐Driven Diseases

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1005-1015, April 2026.
Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin, Stein Schalkwijk, Isabelle J. Pouliquen, Alienor Berges, Nicholas Bird, Richard Follows, Daren Austin   +6 more
wiley   +1 more source