Results 81 to 90 of about 2,437,081 (240)

Nonesophageal Eosinophilic Gastrointestinal Disorders: Clinical Care and Future Directions [PDF]

, 2018
Eosinophilic gastrointestinal disorders are a set of conditions with a wide range of clinical manifestations and treatment modalities. The disorders are suspected to result from an abnormal inflammatory response to allergen(s), and individuals may ...
Gupta, Sandeep K., Naramore, Sara
core   +1 more source

Wells syndrome: clinical findings and management in a large cohort of 48 patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives: Wells syndrome (WS) is a rare inflammatory skin disorder typically characterized by erythematous, edematous, and pruritic plaques. Despite its distinct histopathological features, WS remains an underdiagnosed disease due to its variable clinical presentations and overlap with other dermatological conditions.
Marco Adriano Chessa, Silvia Robuffo, Tullio Brunetti, Luca Rapparini, Bianca Maria Piraccini, Cosimo Misciali, Beatrice Raone, Iria Neri, Federica Filippi   +8 more
wiley   +1 more source

"Idiopathic eosinophilic vasculitis": another side of hypereosinophilic syndrome? A comprehensive analysis of 117 cases in asthma-free patients.

Journal of Allergy and Clinical Immunology: In Practice, 2019
BACKGROUND The absence of asthma may rule out a diagnosis of eosinophilic granulomatosis with polyangiitis (EGPA) in patients with hypereosinophilic syndrome (HES) and features of vasculitis.
G. Lefèvre, A. Leurs, Jean-Baptiste Gibier, M. Copin, D. Staumont‐Sallé, F. Dezoteux, C. Chenivesse, B. Lopez, L. Terriou, E. Hachulla, D. Launay, N. Étienne, M. Labalette, P. Degroote, F. Pontana, T. Quéméneur, P. Hatron, N. Schleinitz, J. Viallard, M. Hamidou, T. Martin, C. Morati-Hafsaoui, M. Groh, M. Lambert, J. Kahn   +24 more
semanticscholar   +1 more source

Association of Eosinophil Counts and Ratios With Clinical Outcomes After Acute Ischemic Stroke

Brain and Behavior, Volume 16, Issue 4, April 2026.
This study demonstrates for the first time that low peripheral eosinophil levels are independent predictors of adverse 5‐year outcomes in ischemic stroke or TIA patients, providing a novel basis for risk stratification and future mechanistic research.
Yangying Lu, Lei Zhang, Hongyi Yan, Yuesong Pan, Jing Jing, Xia Meng, Xingquan Zhao, Liping Liu, Yilong Wang, Yongjun Wang, Honglian Wang, Wenchao Li, Bihong Zhu   +12 more
wiley   +1 more source

The Internal Architecture of Leukocyte Lipid Body Organelles Captured by Three-Dimensional Electron Microscopy Tomography [PDF]

, 2013
Lipid bodies (LBs), also known as lipid droplets, are complex organelles of all eukaryotic cells linked to a variety of biological functions as well as to the development of human diseases.
Dvorak, Ann Marie, Melo, Rossana C. N., Paganoti, Guillherme F., Weller, Peter Fahey   +3 more
core   +7 more sources

Straight to Phase III: Model‐Informed Approach Speeds Depemokimab Clinical Development in Interleukin‐5‐Driven Diseases

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1005-1015, April 2026.
Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin, Stein Schalkwijk, Isabelle J. Pouliquen, Alienor Berges, Nicholas Bird, Richard Follows, Daren Austin   +6 more
wiley   +1 more source

Major Basic Protein Deposition Without Eosinophilic Infiltration in Hypercontractile Esophagus: A Case Report

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Hypercontractile esophagus is a motility disorder characterized by excessive contractions in the esophageal body. Certain cases of hypercontractile esophagus exhibit eosinophilic infiltration in the muscle layer; however, its clinical significance is unclear.
Tetsuya Tatsuta, Keinosuke Hizuka, Shigeharu Ueki, Masatoshi Kaizuka, Shinji Oota, Keisuke Hasui, Hidezumi Kikuchi, Hiroto Hiraga, Daisuke Chinda, Hirotake Sakuraba   +9 more
wiley   +1 more source

Ruxolitinib found to cause eyelash growth: a case report

Journal of Medical Case Reports, 2017
Background Hypereosinophilic syndrome is a hematologic disorder in which the eosinophils proliferate. Oral Janus kinase inhibitors are known to be effective treating hypereosinophilic syndrome.
Julia Song, Alice Song, Trisa Palmares, Michael Song, Harold Song   +4 more
doaj   +1 more source

Idiopathic Eosinophilic Pneumonia with Associated Pulmonary Vasculitis in Horse: A Case Series [PDF]

, 2016
Various eosinophilic lesions and their association with diseases have been described in horses. Multisystemic Eosinophilic Epitheliotropic Disease (MEED) characterized by eosinophilic granulomas in various organs represent the most diffuse manifestation.
Magi, Gian Enrico, Mari, Subeide, Mariotti, Francesca, Rossi, Giacomo   +3 more
core   +1 more source

Comorbid Chronic Rhinosinusitis and Asthma: Shared Risk Factors and Treatment Implications—An EAACI Task Force Report

Allergy, Volume 81, Issue 4, Page 1000-1023, April 2026.
ABSTRACT Chronic rhinosinusitis (CRS) and asthma are prevalent conditions that often coexist. These diseases share common inflammatory mechanisms, such as T‐helper cell 2 (T2)‐high inflammation, driven by interleukin (IL)‐4, IL‐5, and IL‐13 cytokines.
Sanna Toppila‐Salmi, Sietze Reitsma, Valérie Hox, Simon Gane, Philippe Gevaert, Juan Maza‐Solano, Alma Helevä, Ida Sulku, Kaisa Santala, Iiris Kangasniemi, Ludger Klimek, Adam Chaker, Aspasia Karavelia, Michael Rudenko, Oliver Pfaar, Laura Van Gerven, Shaari Ariana, Michele Schiappoli, Marie Lundberg, Jan Hagemann, Ibon Eguíluz‐Gracia, Andre Moreira   +21 more
wiley   +1 more source