Results 61 to 70 of about 1,721 (163)
The Role of Selection for Function in Aging and Chronic Diseases: A Novel Evolutionary Perspective
This conceptual diagram shows how aging alters selection within the body: strong early‐life Darwinian selection prevents aberrant structures, while weakened selective pressure in later life allows persistent damage‐related entities to stabilize. These may reorganize internally, becoming resistant, under a late‐life “selection for function” that favors ...
Antoine M. Dujon +8 more
wiley +1 more source
Acute myocardial infarction is one of the leading causes of death in the world. Owing to the limited regenerative capacity of the heart, the development of therapeutic devices using cell therapy and tissue engineering has gained importance. Preclinical validation of these devices can provide evidence of their safety and efficacy in implantation in ...
Nancy G. Viveros-Moreno +6 more
wiley +1 more source
Shintani functions, real spherical manifolds, and symmetry breaking operators
For a pair of reductive groups $G \supset G'$, we prove a geometric criterion for the space $Sh(\lambda, \nu)$ of Shintani functions to be finite-dimensional in the Archimedean case. This criterion leads us to a complete classification of the symmetric
B. Kostant +6 more
core +1 more source
Background The peripapillary hyperreflective ovoid mass‐like structure (PHOMS) has been defined by the Optic Disc Drusen Studies (ODDS) Consortium as a distinct finding separate from the optic disc drusen (ODD). Given that PHOMS is neither a precursor nor subtype of ODD, its role as an independent risk factor for optic nerve diseases and its secondary ...
Rafaela Saalfeld +4 more
wiley +1 more source
Anaesthesia in adreno-cortical hyperfunction [PDF]
Ľon n’a pas souvent ľoccasion ďanesthesier des patients souffrant ďhypercortico-surrenalisme. La bonne conduite de ces cas de surrenalectomie requiert une parfaite connaissance de la physiopathologie des syndromes ďhypercorticosurrenalisme.
openaire +2 more sources
Are menopause, aging and prostate cancer diseases? [PDF]
Blagosklonny MV.
europepmc +1 more source
Towards disease-oriented dosing of rapamycin for longevity: does aging exist or only age-related diseases? [PDF]
Blagosklonny MV.
europepmc +1 more source
Cellular senescence: when growth stimulation meets cell cycle arrest. [PDF]
Blagosklonny MV.
europepmc +1 more source
This paper is dedicated to the question of surjectivity of the Cauchy-Riemann operator on spaces $\mathcal{EV}(\Omega,E)$ of $\mathcal{C}^{\infty}$-smooth vector-valued functions whose growth on strips along the real axis with holes $K$ is induced by a ...
Kruse, Karsten
core
Rapamycin treatment early in life reprograms aging: hyperfunction theory and clinical practice. [PDF]
Blagosklonny MV.
europepmc +1 more source

