Results 71 to 80 of about 8,688 (201)

Rethinking Common Diagnoses: Idiopathic Multicentric Castleman Disease Presenting as TAFRO Syndrome: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Idiopathic multicentric Castleman disease (TAFRO subtype) can mimic common differentials. High suspicion is required for chronic systemic symptoms and generalized lymphadenopathy. As fine‐needle aspiration is often non‐diagnostic, early excisional biopsy is important.
Divita Rohatgi, Annesha Chakraborty, Sourav Kumar, Anurag Rohatgi   +3 more
wiley   +1 more source

Potent antiretroviral therapy initiates normalization of hypergammaglobulinemia and a decline in HIV type 1-specific antibody responses

, 2001
Next to a profound T cell immunodeficiency, HIV-1 infection induces activation and dysfunction of B cells, resulting in hypergammaglobulinemia. Whereas T cell immune reconstitution with potent antiretroviral therapy has been extensively documented ...
Nijholt, L., Notermans, Daan W., Notermans, D. W., de Ronde, A., Nijholt, Liekle, Roos, M. T., Bakker, M., De Ronde, Anthony, Danner, Sven A., De Jong, J. Jacques, Roos, Marijke T.L., Cremers, J., Cremers, Jeanne, Goudsmit, Jaap, Hellings, J. A., Goudsmit, J., Bakker, Margreet, Hellings, Jan Albert, de Jong, J. J., Danner, S. A.   +19 more
core   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

MyD88 negatively controls hypergammaglobulinemia with autoantibody production during bacterial infection

, 2008
A large body of evidence has convincingly shown that Toll-like receptors are necessary sensors for infections with pathogens, but their activation was also suggested to generate autoimmunity.
Korganow, Anne-Sophie, Jaulhac, Benoit, Knapp, Anne-Marie, Pasquali, Jean-Louis, Martin, Thierry, Woods, Anne, Arditi, Bérénice, Soulas-Sprauel, Pauline   +7 more
core   +1 more source

Hypergammaglobulinemia in Experimental Liver Injury

Experimental Biology and Medicine, 1967
Summary and ConclusionsThe isolated perfused cirrhotic rat liver which is the site of mesenchymal cell proliferation incorporates 3 times as much C14 lysine into serum gamma globulin as the normal liver from litter mate controls. This data is interpreted as further evidence that hypergammaglobulinemia in active cirrhosis results partly from persistent ...
M, Jabbari, C M, Leevy
openaire   +2 more sources

Exercise‐induced vasculitis with histological and genetic evidence of complement involvement

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Massimo Cugno, Paolo Calzari, Alessandra Di Benedetto, Francesca Laura Boggio, Chiara Moltrasio, Luigi Porcaro, Angelo Valerio Marzano   +6 more
wiley   +1 more source

HIV‐1 Vpr Drives a B Cell‐Like Phenotype in Primary CD4+ T Cells

MedComm, Volume 7, Issue 10, October 2026.
During acute HIV‐1 infection, Vpr induces transcriptional and epigenetic remodeling of primary CD4+ T cells, activating a transient B cell‐like program characterized by CD19, MS4A1, CD22, and PAX5 expression and increased chromatin accessibility at lymphocyte differentiation genes.
Peipei Wang, Jieying Li, Wei Wang, Zhuoyue Meng, Huixin Wu, Shumin Du, Kai Deng, Jinfeng Cai   +7 more
wiley   +1 more source

Peptide‐Enabled Nanoplatforms for Malaria and Leishmaniasis: From Intracellular Targeting to Translational Diagnostic Perspectives

ChemMedChem, Volume 21, Issue 18, 28 September 2026.
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales, Ana Clara Lunardi Yagi, Túlio Custódio Reis, Jessica Ingrid Cazorla, Jade Rojas Villar, Marcia A. Graminha, Roxana Yesenia Pastrana Alta, Fernando Rogério Pavan   +7 more
wiley   +1 more source

Autoimmune Hepatitis and Systemic Sclerosis: a Rare Association

European Journal of Case Reports in Internal Medicine, 2019
A woman in her early 40s, with a history of excessive alcohol intake, presented with purpuric, ulcerative lesions on the lower limbs. On examination, hirsutism and generalized stiffening and thickening of the skin were noted.
Elisabete Pereira Coelho, Ana Rita Matos, Sofia Caridade   +2 more
doaj   +1 more source

Solitary crystal-storing histiocytosis of the tongue in a patient with rheumatoid arthritis and polyclonal hypergammaglobulinemia

, 1998
A 73-year-old woman with a long history of rheumatoid arthritis and polyclonal hypergammaglobulinemia developed a solitary mass in the tongue, which on morphologic and immunohistochemical analyses was consistent with crystal-storing histiocytosis, a rare
C. Bosman, CORSI, ALESSANDRO, R. Romeo, M. Saponara, F. D. Camassei, R. Boldrini, F. R. Piro   +6 more
core