Results 71 to 80 of about 10,973 (224)

Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease

open access: yesArthritis &Rheumatology, Volume 78, Issue 3, Page 566-581, March 2026.
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman   +2 more
wiley   +1 more source

Hypergammaglobulinemia in Experimental Liver Injury

open access: yesExperimental Biology and Medicine, 1967
Summary and ConclusionsThe isolated perfused cirrhotic rat liver which is the site of mesenchymal cell proliferation incorporates 3 times as much C14 lysine into serum gamma globulin as the normal liver from litter mate controls. This data is interpreted as further evidence that hypergammaglobulinemia in active cirrhosis results partly from persistent ...
M, Jabbari, C M, Leevy
openaire   +2 more sources

Non‐Specific Interstitial Pneumonia in Anti‐Jo1 Synthetase Syndrome With Probable Gougerot Syndrome: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Anti‐synthetase syndrome (ASS) is a rare autoimmune disorder of idiopathic inflammatory myopathy spectrum, characterized by the presence of aminoacyl‐tRNA synthetase antibodies, most commonly anti‐Jo‐1. Clinically presents with interstitial lung disease (ILD), myositis, and arthritis, and may be confused with other autoimmune conditions such ...
Ali Gohar   +7 more
wiley   +1 more source

Autoimmune Hepatitis and Systemic Sclerosis: a Rare Association

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2019
A woman in her early 40s, with a history of excessive alcohol intake, presented with purpuric, ulcerative lesions on the lower limbs. On examination, hirsutism and generalized stiffening and thickening of the skin were noted.
Elisabete Pereira Coelho   +2 more
doaj   +1 more source

Expert‐Designed Fact Sheets and AI‐Based Analysis of Patient Symptoms to Combat Diagnostic Delays in Inherited Metabolic Diseases

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT The importance of early diagnosis of inherited metabolic diseases (IMDs) is well known, as it allows early intervention to prevent or reduce complications and improve prognosis, since many of these disorders are treatable. However, diagnosis can still be delayed, and many patients remain undiagnosed. Reducing diagnosis delays is a primary goal
Aline Cano   +108 more
wiley   +1 more source

Rapidly progressive immunoglobulin M monoclonal gammopathy presenting with nephrotic syndrome and hepatic failure

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2020
We report a 73-year-old male with no relevant past medical history who presented with nephrotic syndrome and jaundice. Subsequent studies revealed immunoglobulinM (IgM) monoclonal gammopathy.
Yao-Ko Wen
doaj   +1 more source

Diagnosis of some diseases through biomarkers [PDF]

open access: yes, 2019
Muchos gatos, como los perros, sufren de diferentes enfermedades. que en ese momento no permiten mostrar síntomas o signos que permiten identificar que la mascota sufre una enfermedad grave, ya que las características de los gatos son diferentes a las de
Gutiérrez Rodríguez, Andrea
core  

Conjugal Secondary Syphilis With Divergent Cutaneous Manifestations: Papulonodular Variant

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
Secondary syphilis (Papulonodular variant). Multiple erythematous papules and nodules on the (a) left side of the neck, (b) posterior neck, and (c) face. (d) Solitary indurated, erythematous papule over the shaft of the penis (arrow). ABSTRACT Syphilis should be considered in patients with atypical papulonodular eruptions, as even conjugal cases may ...
Mahesh Mathur   +5 more
wiley   +1 more source

Combined atypical primary hypoadrenocorticism and primary hypothyroidism in a dog [PDF]

open access: yes, 2016
A dog with combined atypical primary hypoadrenocorticism and primary hypothyroidism is described. The dog presented with waxing and waning, vague complaints since more than a year and had been treated with several drugs without complete resolution of ...
Binst, Dominique   +5 more
core  

Effect of ligands to toll-like receptors (TLR) 3, 7 and 9 on mice infected with mouse hepatitis virus A59 [PDF]

open access: yes, 2014
Mice infected with mouse hepatitis virus A59 (MHV-A59), an enveloped, positive-strand RNA Co-ronavirus, induce hepatitis, thymus involution, IgG2a-restricted hypergammaglobulinaemia, transaminase release and autoantibodies (autoAb) to liver and kidney ...
Aparicio, Jose Luis   +2 more
core   +1 more source

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