Results 61 to 70 of about 8,688 (201)

Failure to thrive and hypergammaglobulinemia in a 13-year-old girl with Castleman Disease, a case report

, 2023
Castleman Disease is a rare, lymphoproliferative, non-malignant disorder with two subtypes, unicentric or multicentric, depending on the number of lymph node regions affected.
Van Parys, Hélène, Chantrain, Christophe, Beckers, Dominique, Tuerlinckx, David, Somja, Joan   +4 more
core   +1 more source

European Consortium for Lipodystrophies consensus definition and classification framework for monogenic lipodystrophy

Journal of Internal Medicine, EarlyView.
Abstract Lipodystrophy comprises a heterogeneous group of disorders characterized by reduced adipose tissue often associated with severe metabolic complications. Lipodystrophy may be genetic, acquired, or secondary to medical therapies initiated for other conditions.
Robert K. Semple, Martin Wabitsch, Baris Akinci, Saif Alyaarubi, Marjoleine F. Broekema, Rebecca J. Brown, Giovanni Ceccarini, Carolina Cecchetti, Solaf M. Elsayed, Antía Fernández‐Pombo, Alessandra Gambineri, Ingrid M. Jazet, Lotte Kleinendorst, Konstanze Miehle, Elif A. Oral, Flavia Prodam, Ferruccio Santini, David B. Savage, Nadia Shaukat Ali, Ekaterina Sorkina, Magdalena Szopa, Marie‐Christine Vantyghem, Camille Vatier, Corinne Vigouroux, Julia von Schnurbein, David Araújo‐Vilar   +25 more
wiley   +1 more source

A Case of Lethal Idiopathic Plasmacytic Lymphadenopathy with Polyclonal Hypergammaglobulinemia: A Medical Challenge for the Forensic Pathologist

, 2016
A rare case of lethal idiopathic plasmacytic lymphadenopathy (IPL) with polyclonal hyperimmunoglobulinemia with chronic renal failure is described. A 40-year-old woman who had suffered from upper airways disease was admitted to the Emergency Room with ...
Solarino B., Di Vella G., Tattoli L., Schiraldi O.   +3 more
core   +1 more source

Patient Journey, Disease Burden, Treatment Patterns, and the Impact of Delayed Diagnosis Among Patients With Sjögren's Disease: A Real‐World US Survey

ACR Open Rheumatology, Volume 8, Issue 10, October 2026.
Objective The aim of this study was to investigate disease burden, treatment patterns, and impact of delayed diagnosis on patient outcomes in Sjögren's disease (SjD) in a real‐world setting in the United States. Methods Data were drawn from the Adelphi Primary Sjögren's Syndrome Disease Specific Programme, a US‐based cross‐sectional collaborative ...
Anjana Lalla, Antton Egana, Jack Milligan, Nicola Massey, James Haughton   +4 more
wiley   +1 more source

Correlation Between Dermal Interstitial Immunoglobulin G and Hypergammaglobulinemia [PDF]

, 1991
The diffuse dermal immunofluorescence (DDIF) observed in human skin biopsies that is produced by fluorochrome-conjugated antisera reactive with human immunoglobulin G (IgG) has commonly been viewed in the past as an artifact of direct immunofluorescence ...
Sontheimer, Richard D, Lieu, Tsu-San, Brown, Christine   +2 more
core   +1 more source

Active chronic sarcoidosis is characterized by increased transitional blood B cells, increased IL-10-producing regulatory B cells and high BAFF levels.

PLoS ONE, 2012
BackgroundSarcoidosis is a multisystemic disease of unknown etiology characterized by a disproportionate Th1 granulomatous immune response in the organs involved.
Anne Saussine, Abdellatif Tazi, Séverine Feuillet, Michel Rybojad, Caroline Juillard, Anne Bergeron, Valérie Dessirier, Fatiha Bouhidel, Anne Janin, Armand Bensussan, Martine Bagot, Jean-David Bouaziz   +11 more
doaj   +1 more source

IgG4‐to‐IgG Ratio and Orbital Involvement Predict Clinical Response to B Cell Depletion in IgG4‐Related Disease

ACR Open Rheumatology, Volume 8, Issue 10, October 2026.
Objective IgG4‐related disease (RD) demonstrates ethnic variations in phenotype, but data from diverse US populations are limited. We characterized ethnic differences in organ involvement and evaluated predictors of treatment response in a multiethnic cohort.
Young Min Cho, Alejandro Quinteros, Pallavi Khattar, Morris Clive Edelman, Lara El Khoury, Galina Marder   +5 more
wiley   +1 more source

Candidate SNP markers of gender-biased autoimmune complications of monogenic diseases are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters

Frontiers in Immunology, 2016
Some variations of human genome (for example, single nucleotide polymorphisms [SNPs]) are markers of hereditary diseases and drug responses. Analysis of them can help to improve treatment.
Mikhail P. Ponomarenko
doaj   +1 more source

POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, Volume 101, Issue 10, Page 2632-2651, October 2026.
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley   +1 more source

IgG abnormalities in HIV-positive Malawian women initiating antiretroviral therapy during pregnancy persist after 24 months of treatment

International Journal of Infectious Diseases, 2019
Objectives: Hypergammaglobulinemia and anomalies in the IgG subclass distribution are common in HIV-infected individuals and persist even after many years of antiretroviral therapy (ART).
Silvia Baroncelli, Clementina Maria Galluzzo, Giuseppe Liotta, Stefano Orlando, Fausto Ciccacci, Mauro Andreotti, Robert Mpwhere, Richard Luhanga, Jean Baptiste Sagno, Roberta Amici, Maria Cristina Marazzi, Marina Giuliano   +11 more
doaj   +1 more source