Results 61 to 70 of about 8,104 (203)

Active chronic sarcoidosis is characterized by increased transitional blood B cells, increased IL-10-producing regulatory B cells and high BAFF levels.

PLoS ONE, 2012
BackgroundSarcoidosis is a multisystemic disease of unknown etiology characterized by a disproportionate Th1 granulomatous immune response in the organs involved.
Anne Saussine, Abdellatif Tazi, Séverine Feuillet, Michel Rybojad, Caroline Juillard, Anne Bergeron, Valérie Dessirier, Fatiha Bouhidel, Anne Janin, Armand Bensussan, Martine Bagot, Jean-David Bouaziz   +11 more
doaj   +1 more source

Candidate SNP markers of gender-biased autoimmune complications of monogenic diseases are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters

Frontiers in Immunology, 2016
Some variations of human genome (for example, single nucleotide polymorphisms [SNPs]) are markers of hereditary diseases and drug responses. Analysis of them can help to improve treatment.
Mikhail P. Ponomarenko
doaj   +1 more source

New‐Onset Acute Heart Failure With Reduced Ejection Fraction Associated With Severe Microcytic Anemia

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Graphical abstract summarizing a case of new‐onset HFrEF associated with profound microcytic anemia, highlighting severe anemia as a potential reversible trigger of acute cardiac decompensation. ABSTRACT Severe microcytic anemia may serve as a potentially reversible precipitating factor in heart failure with reduced ejection fraction (HFrEF). This case
Annabel Ricci, Cassandra Hunt, Chabelly Gomez, Gerson Santafe, Aimee Gonzalez, Martha Duarte   +5 more
wiley   +1 more source

IgG abnormalities in HIV-positive Malawian women initiating antiretroviral therapy during pregnancy persist after 24 months of treatment

International Journal of Infectious Diseases, 2019
Objectives: Hypergammaglobulinemia and anomalies in the IgG subclass distribution are common in HIV-infected individuals and persist even after many years of antiretroviral therapy (ART).
Silvia Baroncelli, Clementina Maria Galluzzo, Giuseppe Liotta, Stefano Orlando, Fausto Ciccacci, Mauro Andreotti, Robert Mpwhere, Richard Luhanga, Jean Baptiste Sagno, Roberta Amici, Maria Cristina Marazzi, Marina Giuliano   +11 more
doaj   +1 more source

ERDHEIM‐Chester Disease: Two Fatal Cases With Unusual Presentations

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Fluorodeoxyglucose positron emission tomography‐computed tomography (FDG PET‐CT) demonstrated markedly increased metabolic activity in serosal surfaces including pericardium, pleura, and renal fascia, as well as diffuse uptake along vascular walls, particularly the entire aorta.
Ribero‐Vargas Daniel Andres, C. Álvarez Payares José, Murillo‐Pérez Juliana   +2 more
wiley   +1 more source

MyD88 negatively controls hypergammaglobulinemia with autoantibody production during bacterial infection

, 2008
A large body of evidence has convincingly shown that Toll-like receptors are necessary sensors for infections with pathogens, but their activation was also suggested to generate autoimmunity.
Korganow, Anne-Sophie, Jaulhac, Benoit, Knapp, Anne-Marie, Pasquali, Jean-Louis, Martin, Thierry, Woods, Anne, Arditi, Bérénice, Soulas-Sprauel, Pauline   +7 more
core   +1 more source

Exercise‐induced vasculitis with histological and genetic evidence of complement involvement

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Massimo Cugno, Paolo Calzari, Alessandra Di Benedetto, Francesca Laura Boggio, Chiara Moltrasio, Luigi Porcaro, Angelo Valerio Marzano   +6 more
wiley   +1 more source

Potent antiretroviral therapy initiates normalization of hypergammaglobulinemia and a decline in HIV type 1-specific antibody responses

, 2001
Next to a profound T cell immunodeficiency, HIV-1 infection induces activation and dysfunction of B cells, resulting in hypergammaglobulinemia. Whereas T cell immune reconstitution with potent antiretroviral therapy has been extensively documented ...
Nijholt, L., Notermans, Daan W., Notermans, D. W., de Ronde, A., Nijholt, Liekle, Roos, M. T., Bakker, M., De Ronde, Anthony, Danner, Sven A., De Jong, J. Jacques, Roos, Marijke T.L., Cremers, J., Cremers, Jeanne, Goudsmit, Jaap, Hellings, J. A., Goudsmit, J., Bakker, Margreet, Hellings, Jan Albert, de Jong, J. J., Danner, S. A.   +19 more
core   +1 more source

Polyclonal hypergammaglobulinemia and high smooth-muscle autoantibody titers with specificity against filamentous actin: consider visceral leishmaniasis, not just autoimmune hepatitis

, 2009
SummaryVisceral leishmaniasis (VL) remains a public health problem in most countries bordering the Mediterranean basin. Its diagnosis is challenging and often delayed, as the main clinical picture is often indistinguishable from that of other infectious ...
Dalekos, G. N., Makaritsis, K. P., Dalekos, George N., Makaritsis, Konstantinos P., Petinaki, Efthimia, Gatselis, N. K., Gatselis, Nikolaos K., Ioannou, M., Ioannou, Maria, Petinaki, E.   +9 more
core   +1 more source

Hypergammaglobulinemia in Experimental Liver Injury

Experimental Biology and Medicine, 1967
Summary and ConclusionsThe isolated perfused cirrhotic rat liver which is the site of mesenchymal cell proliferation incorporates 3 times as much C14 lysine into serum gamma globulin as the normal liver from litter mate controls. This data is interpreted as further evidence that hypergammaglobulinemia in active cirrhosis results partly from persistent ...
M, Jabbari, C M, Leevy
openaire   +2 more sources