Results 61 to 70 of about 10,973 (224)

Interfollicular Plasmacytosis and Hyperplastic Germinal Centers in Idiopathic Multicentric Castleman Disease, Idiopathic Plasmacytic Lymphadenopathy Subtype

American Journal of Hematology, EarlyView.
Stephanie Quon, Clarissa Skorupski, Christophe Langlois, Lee Mozessohn, Carlo Hojilla, Luke Y. C. Chen   +5 more
wiley   +1 more source

NEMO‐NDAS: Case Report and Review of the Literature

Pediatric Dermatology, EarlyView.
ABSTRACT NEMO‐deleted exon 5 autoinflammatory syndrome (NEMO‐NDAS) is the result of a gain‐of‐function IKBKG pathogenic variant leading to dysregulated NF‐κB signaling and systemic inflammation. We present a case of NEMO‐NDAS in a 2‐year‐old female presenting with recurrent fevers, subcutaneous nodules, lymphadenopathy, and splenomegaly.
Angela Yang, Kristie Mar, Kimberly A. Morishita, Kevin Meesters, Antonio Torrelo, Joseph M. Lam   +5 more
wiley   +1 more source

Telbivudine on IgG-associated hypergammaglobulinemia and TGF-β1 hyperactivity in hepatitis B virus-related liver cirrhosis.

PLoS ONE, 2019
As debate rumbles on about whether anti-hepatitis B virus (HBV) nucleos(t)ide analogue treatments modulate host immune system during end-stage liver diseases, we studied effects of two potent anti-HBV agents, telbivudine or entecavir, on humoral immune ...
Cheng-Hsun Ho, Ting-Tsung Chang, Rong-Nan Chien   +2 more
doaj   +1 more source

Active chronic sarcoidosis is characterized by increased transitional blood B cells, increased IL-10-producing regulatory B cells and high BAFF levels.

PLoS ONE, 2012
BackgroundSarcoidosis is a multisystemic disease of unknown etiology characterized by a disproportionate Th1 granulomatous immune response in the organs involved.
Anne Saussine, Abdellatif Tazi, Séverine Feuillet, Michel Rybojad, Caroline Juillard, Anne Bergeron, Valérie Dessirier, Fatiha Bouhidel, Anne Janin, Armand Bensussan, Martine Bagot, Jean-David Bouaziz   +11 more
doaj   +1 more source

Factors Affecting the FcRn-Mediated Transplacental Transfer of Antibodies and Implications for Vaccination in Pregnancy. [PDF]

, 2017
At birth, neonates are particularly vulnerable to infection and transplacental transfer of immunoglobulin G (IgG) from mother to fetus provides crucial protection in the first weeks of life.
Abdiche, Abourawi, Abu-Raya, Amirthalingam, Amirthalingam, Antohe, Atwell, Bainbridge, Bakchoul, Baker, Baker, Basha, Bialas, Bondt, Brair, Brambell, Brambell, Brambell, Bruhns, Calderon, Calvert, Cavalcante, Chen, Chu, Cumberland, Dabrera, Dashivets, de Moraes-Pinto, de Souza, Dillon, Einarsdottir, Einarsdottir, Ellinger, Ellinger, Englund, Faucette, Faucette, Firan, Fowden, França, Fu, Gaither, Gall, Goldfarb, Griffiths, Hamilton, Hammes, Hanson, Hartter, Hashira, Heath, Heidl, Henkle, Heron, Holder, Holland, Hornby, Huhn, Jansen, Jauniaux, Jefferis, Jones, Junghans, Kennedy, Kibe, Kim, Kim, Kim, Kohler, Kristoffersen, Ladhani, Leach, Leitner, Li, Li, Lightle, Madhi, Maertens, Malek, Malek, Mammaro, Martin, Martins, Mathiesen, Mathiesen, Medesan, Mestas, Mimura, Mitchell, Mohanty, Montano, Moore, Myllynen, Neuber, Niewiesk, Ober, Ober, Oganesyan, Okoko, Okoko, Okoko, Okoko, Omata, Osendarp, Palmeira, Palmer, Poehling, Porter, Poulsen, Powner, Qiao, Raghavan, Raghavan, Reynolds, Roux, Sand, Saso, Schlaudecker, Schofield, Scott, Sgarbosa, Silveira Lessa, Simister, Simister, Simister, Stach, Stapleton, Stapleton, Syme, Tabata, Takizawa, Tapia, Thomann, Tzaban, van den Berg, van den Berg, Viall, Vidarsson, Vidarsson, Vogelzang, Vähäkangas, West, Williams, Winter, Wormald, Wypych, Zaman, Zhu   +147 more
core   +2 more sources

Identification of a Novel De Novo Heterozygous SEC61A1 Variant in a Patient With Severe Congenital Neutropenia

Molecular Genetics &Genomic Medicine, Volume 14, Issue 5, May 2026.
Severe congenital neutropenia can be caused by rare SEC61A1 variants. We report a child with SCN showing granulocytic maturation arrest and abnormal immunophenotype, carrying a novel de novo SEC61A1 p.Trp379Arg variant, expanding the phenotypic and genetic spectrum of SEC61A1‐associated SCN.
Zixuan Wang, Hui Jing, Yuhan Chen, Ling Zhong, Jiyun Yang   +4 more
wiley   +1 more source

Candidate SNP markers of gender-biased autoimmune complications of monogenic diseases are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters

Frontiers in Immunology, 2016
Some variations of human genome (for example, single nucleotide polymorphisms [SNPs]) are markers of hereditary diseases and drug responses. Analysis of them can help to improve treatment.
Mikhail P. Ponomarenko
doaj   +1 more source

Sustained Belinostat‐Induced Metabolic Response and Tolerability in Heavily Pretreated Relapsed/Refractory Angioimmunoblastic T‐Cell Lymphoma: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Angioimmunoblastic T‐cell lymphoma (AITL), a rare and aggressive subtype of peripheral T‐cell lymphoma (PTCL), often demonstrates resistance to standard therapies. The optimal therapeutic approach for relapsed/refractory (R/R) AITL remains therefore uncertain and challenging, with an unmet need for effective treatment options.
Vassiliki Labropoulou, Evgenia Verigou, Eleni P. Kourea, Maria Liga, Dimitrios Tsokanas, Krisela‐Christina Valera, Alexandros Spyridonidis   +6 more
wiley   +1 more source

IgG abnormalities in HIV-positive Malawian women initiating antiretroviral therapy during pregnancy persist after 24 months of treatment

International Journal of Infectious Diseases, 2019
Objectives: Hypergammaglobulinemia and anomalies in the IgG subclass distribution are common in HIV-infected individuals and persist even after many years of antiretroviral therapy (ART).
Silvia Baroncelli, Clementina Maria Galluzzo, Giuseppe Liotta, Stefano Orlando, Fausto Ciccacci, Mauro Andreotti, Robert Mpwhere, Richard Luhanga, Jean Baptiste Sagno, Roberta Amici, Maria Cristina Marazzi, Marina Giuliano   +11 more
doaj   +1 more source

Idiopathic sclerosing mesenteritis in paediatrics: Report of a successfully treated case and a review of literature [PDF]

, 2010
A 6 year old female with symptoms of small bowel obstruction underwent an exploratory laparotomy which revealed widespread evidence of inflammatory fibrotic adhesions involving the jejunal mesentery. In view of persistent growth failure, chronic anaemia,
Vijay Viswanathan, Kevin J Murray, JV Sulla, AL Durst, N Vettoretto, B White, TS Emory, S Akram, A Bala, Re Kipfer, E Parra-Davila, A Schaffler, G Hakguder, A Schaffler, RH Phillips, H Medina Franco, TS Chen, AM Dor, KH Soergel, RB Spark, HJ McGee, W Black, S Kawano, CR Melo, O Cakmak, JZ Jona, CF Davis, D Ueda, SY Han, A Soler, N Roson, KM Horton, JM Sabate, AJ Kronthal, PM Ginsburg, KH Katsanos, JK Serelis   +36 more
core   +1 more source