Results 41 to 50 of about 10,973 (224)

Asymptomatic flow of Rosai-Dorfman disease [PDF]

, 2014
Introduction. Sinus histiocytosis with massive lymphadenopathy is a rare benign self-limiting disease of unknown etiology. The salivary gland involvement, indicating the extranodal character of the disease, often presents a diagnostic dilemma ...
Bjelaković Bojko, Kesić Ljiljana, Kostić Miloš, Mihailović Dragan, Mijovićć Žaklina, Petrović Dragan, Petrović Milica, Petrović Slađana, Stanković Ana, Vučković Ivica, Živković Nikola   +10 more
core   +1 more source

Immunoglobulin abnormalities are frequent in patients with lupus nephritis

BMC Rheumatology, 2019
Background Hypogammaglobulinemia is a complication of B-cell targeting therapies (BCTT), used in vasculitis, rheumatoid arthritis and systemic lupus erythematosus (SLE).
M. J. Cuadrado, I. Calatayud, M. Urquizu-Padilla, S. Wijetilleka, S. Kiani-Alikhan, M. Y. Karim   +5 more
doaj   +1 more source

Idiopathic Multicentric Castleman Disease with Strikingly Elevated IgG4 Concentration in the Serum and Abundant IgG4-Positive Cells in the Tissue: A Case Report

Diagnostics, 2022
Idiopathic multicentric Castleman disease (iMCD) can be challenging to distinguish clinically and histopathologically from Immunoglobulin G4-related disease (IgG4RD).
Chia-Chun Cheng, Ying-Chu Chen, Yung-Hsiang Hsu, Kuei-Ying Su   +3 more
doaj   +1 more source

REGULATORY ROLE OF OX22HIGH T-CELLS IN MERCURY-INDUCED AUTOIMMUNITY IN THE BROWN NORWAY RAT [PDF]

, 1993
The monoclonal antibody OX22 defines a functional split within CD4+ T cells in the rat, with OX22high cells mainly producing interleukin 2 (IL-2) and interferon γ and responsible for delayed-type hypersensitivity responses, and OX22low cells mainly ...
Mathieson, PW, Oliveira, DB, Thiru, S
core   +1 more source

Immune Complexes Shape the Pathogenicity of Autoantibodies in Systemic Autoimmune Diseases: Insights From an FcγRIIIA‐Reporter Assay

Arthritis &Rheumatology, EarlyView.
Objective Immune complexes (ICs), formed by autoantigen and autoantibody, play a pathogenic role in systemic autoimmune diseases through stimulation of Fcγ receptors (FcγR). However, studies investigating bioactivity of circulating ICs across various diseases remain limited.
Koji Suzuki, Masaru Takeshita, Yuki Imai, Hiroyuki Fukui, Kazunori Furuhashi, Kotaro Matsumoto, Jun Kikuchi, Keiko Yoshimoto, Yuko Kaneko   +8 more
wiley   +1 more source

Primary cutaneous plasmacytosis: Masquerading as hidradenitis suppurativa

Indian Journal of Dermatology, 2016
Isolated cutaneous plasmacytosis (CP) is a rare entity with few cases reported in world literature. CP masquerading as hidradenitis suppurativa like presentation is a unique case with some features differentiating it clinically from it which were further
Tarang Goyal, Anupam Varshney, Vijay Zawar, Veena Sharma   +3 more
doaj   +1 more source

Clock genes regulate Ca2+ signaling and mitochondrial bioenergetics to inhibit Sjogren's disease

Arthritis &Rheumatology, Accepted Article.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjogren's disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA seq, and mitochondrial activity were used to investigate the effects of ...
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento Da Conceicao, Neelanjan Vishnu, Shankara N Varadarajan, Venugopal R. Bovilla, Rajender K Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Protozoan Parasites and Type I IFNs [PDF]

, 2017
International audienceFor many years, the role of interferon (IFN)-I has been characterized primarily in the context of viral infections. However, regulatory functions mediated by IFN-I have also been described against bacterial infections and in tumor ...
Aichele, Amin, Aucan, Ball, Bankoti, Bankoti, Bertolino, Blader, Bogdan, Cardoso, Carrero, Chakravarty, Chaussabel, Chessler, Chessler, Chessler, Costa, Costales, Darde, de Weerd, Deak, Diefenbach, Diez, Dupont, Egli, Elmore, Emamian, Engin, Engwerda, Fallet, Favila, Fink, Han, Han, Haque, Haque, Herman, Isaacs, Ito, Ivashkiv, Jahiel, James, Javed, Kaye, Kearney, Khouri, Ko, Kolumam, Krupka, Le Bon, Liehl, Lopez, Lund, MacGregor, Mahmoud, Manna, Marrack, Martin, Mattner, Mattner, Mayer-Barber, McNab, McNab, Miller, Mogensen, Montoya, Morrell, Moseman, Murray, Nagineni, Namangala, Ng, Obeid, Olekhnovitch, Omata, Orellana, Passwell, Pfefferkorn, Platanias, Portugal, Rayamajhi, Remington, Riley, Rocha, Rosowski, Rottenberg, Scharton-Kersten, Schmitz, Schoenborn, Schofield, Shirahata, Sibley, Silva-Barrios, Smelt, Stevenson, Tamura, Teijaro, Trau, Trinchieri, Une, Urban, Vaena de Avalos, Vigario, Vincendeau, Vossenkämper, Wilson, Wilson, Wu, Xin   +108 more
core   +3 more sources

Validation of a Multiparametric, Automated, Macroarray‐Based Assay for the Detection of Autoantibodies in Autoimmune Liver Disease

Journal of Clinical Laboratory Analysis, EarlyView.
The assay exploited a multiparametric and fully automated device applied to CHORUS EVO to validate that the CHORUS Macroarray Liver Diseases kit is a novel procedure for detecting autoantibodies of AIH and PBC. The assay resulted as linear, accurate, sensitive, specific, and able to distinguish between PBC and AIH.
Luigi Raganelli, Tommaso Bandini, Matilde Ilacqua, Helena Cerutti, Alessandra Cartocci, Giulia Tesi, Andrea Ianniello, Thomas Massari, Mirko Berretti, Roberto Centini, Michele Norelli, Alessandra Brogi, Giampaola Pesce, Danilo Villalta, Brunetta Porcelli   +14 more
wiley   +1 more source