Results 31 to 40 of about 8,688 (201)

Macroglobulinemia de Waldenström - remissão completa após tratamento com rituximabe Successful outcome in Waldenström's macroglobulinemia treated with rituximab

Revista Brasileira de Hematologia e Hemoterapia, 2008
A macroglobulinemia de Waldenström (MW) é uma patologia rara dos linfócitos B caracterizada pela produção monoclonal de IgM, e que pode manifestar-se clinicamente com fadiga, astenia, perda de peso, sangramento de mucosas e do trato gastrintestinal ...
Flavia C. F. Pimenta, Melina P. Fernandes, Amanda R. M. Lima, Margareth F. M. Diniz, Maria Angelina C. F. Fernandes, Sandra M. C. C. Esteves, Lenísio B. de Araújo   +6 more
doaj   +1 more source

Congenital Human Cytomegalovirus Infection Is Associated With Decreased Transplacental IgG Transfer Efficiency Due to Maternal Hypergammaglobulinemia

, 2021
BACKGROUND: Placentally transferred maternal immunoglobulin G (IgG) protects against pathogens in early life, yet vertically transmitted infections can interfere with transplacental IgG transfer.
Fouda, Genevieve G, Walsh, Kyle M, Yang, Zidanyue, Permar, Sallie R, Li, Shuk Hang, Semmes, Eleanor C, Niedzwiecki, Donna, Hurst, Jillian H, Kurtzberg, Joanne   +8 more
core   +1 more source

n Autopsy Case of Malignant Hemangicendotheliomatosis of Bone Marrow Accompanied by Hypergammaglobulinemia. [PDF]

, 1968
An autopsy case of 25-year-old male who had complaints of anemia, remittent fever, pains referable to bones, emaciation, and jaundice is presented.
佐々木, 喬敏, 藤本, 輝夫, 池田, 成之, 福田, 守道, 小山, 隆三, 坂本, 真一   +5 more
core   +1 more source

Polyclonal Hypergammaglobulinemia in a Randomized Sample of Ghanaian Adult Males

, 2007
Introduction Diffuse or polyclonal hypergammaglobulinemia has been associated with multiple medical conditions such as autoimmune diseases, infections, and chronic liver diseases.
Pfeiffer, Ruth M., Biritwum, Richard B., Hsing, Ann W., Kyle, Robert, Dispenzieri, Angela, Buadi, Francis, Landgren, Ola, Katzmann, Jerry A., Yeboah, Edward D., Rajkumar, Vincent, Landgren, Carl   +10 more
core   +1 more source

Induction of Hypergammaglobulinemia and Autoantibodies by Salmonella Infection in MyD88-Deficient Mice

Frontiers in Immunology, 2018
Growing evidence indicates a link between persistent infections and the development of autoimmune diseases. For instance, the inability to control Salmonella infection due to defective toll-like receptor (TLR)/myeloid differentiation primary response 88 (
Jincy M. Issac, Yassir A. Mohamed, Ghada Hassan Bashir, Ashraf Al-Sbiei, Walter Conca, Taj A. Khan, Asif Iqbal, Gabriela Riemekasten, Katja Bieber, Ralf J. Ludwig, Otavio Cabral-Marques, Maria J. Fernandez-Cabezudo, Basel K. al-Ramadi   +12 more
doaj   +1 more source

Cryptogenic hepatic abscess in an infant and management challenges in a resource limited setting: a case report

Egyptian Pediatric Association Gazette, 2023
Background Pyogenic liver abscess is a rare condition in children especially in early infancy. The diagnosis requires a high index of suspicion and treatment has to be aggressive to avoid fatality. There is a rarity of reports of the condition in infancy
Oluwafunmilayo Funke Adeniyi, Nelson Daniel, Olivia Ashefor, Patricia Akintan   +3 more
doaj   +1 more source

Multiple myeloma in a dog

Brazilian Journal of Veterinary Pathology, 2008
Multiple myeloma is an uncommon malignant neoplastic disease of humans and domestic animals associated with the excessive production of immunoglobulin by proliferated plasma cells.
Patrícia F. N. da Silva, Ana P. F. R. L. Bracarense, Laurence G. von Galen, Claudia C. B. Grotti, Mara R. S. Balarin, Tizianne L. D. R. Nakagawa, Vitor S. de Melo, Mônica V. B. Arias, Antônio C. F. dos Reis, Selwyn A. Headley   +9 more
doaj   +1 more source

Immune Complexes Shape the Pathogenicity of Autoantibodies in Systemic Autoimmune Diseases: Insights From an FcγRIIIA‐Reporter Assay

Arthritis &Rheumatology, EarlyView.
Objective Immune complexes (ICs), formed by autoantigen and autoantibody, play a pathogenic role in systemic autoimmune diseases through stimulation of Fcγ receptors (FcγR). However, studies investigating bioactivity of circulating ICs across various diseases remain limited.
Koji Suzuki, Masaru Takeshita, Yuki Imai, Hiroyuki Fukui, Kazunori Furuhashi, Kotaro Matsumoto, Jun Kikuchi, Keiko Yoshimoto, Yuko Kaneko   +8 more
wiley   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

Arthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento da Conceicao, Neelanjan Vishnu, Shankara N. Varadarajan, Venugopal R. Bovilla, Rajender K. Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Immunoglobulin abnormalities are frequent in patients with lupus nephritis

BMC Rheumatology, 2019
Background Hypogammaglobulinemia is a complication of B-cell targeting therapies (BCTT), used in vasculitis, rheumatoid arthritis and systemic lupus erythematosus (SLE).
M. J. Cuadrado, I. Calatayud, M. Urquizu-Padilla, S. Wijetilleka, S. Kiani-Alikhan, M. Y. Karim   +5 more
doaj   +1 more source