Results 51 to 60 of about 8,104 (203)

A retrospective study of the relative utility of electrophoresis in the investigation of serum proteins

Universa Medicina
Background Serum protein electrophoresis (SPE) is widely used for diagnosis, management and monitoring of different immune disorders. Serum protein alterations provide valuable insights about these disorders.
Gusdanis Alberto Campos García, Yulien Fernández Romay , Naga Raju Maddela, Aron Zamora Cedeño , Diego Talledo Pinargote , Ivón Howland Álvarez   +5 more
doaj   +1 more source

NEMO‐NDAS: Case Report and Review of the Literature

Pediatric Dermatology, EarlyView.
ABSTRACT NEMO‐deleted exon 5 autoinflammatory syndrome (NEMO‐NDAS) is the result of a gain‐of‐function IKBKG pathogenic variant leading to dysregulated NF‐κB signaling and systemic inflammation. We present a case of NEMO‐NDAS in a 2‐year‐old female presenting with recurrent fevers, subcutaneous nodules, lymphadenopathy, and splenomegaly.
Angela Yang, Kristie Mar, Kimberly A. Morishita, Kevin Meesters, Antonio Torrelo, Joseph M. Lam   +5 more
wiley   +1 more source

Expansion of Tfh-like cells during chronic Salmonella exposure mediates the generation of autoimmune hypergammaglobulinemia in MyD88-deficient mice

, 2011
The role of TLR signaling in linking the innate and adaptive immune systems has been a controversial issue that remains to be solved. Here, we determined whether MyD88-dependent TLR signals are required for the generation of B-cell responses during ...
Mi-Na Kweon, Kweon, Mi-Na, Chang, Sun-Young, Yang, Hyungjun, Sang-Uk Seo, Sun-Young Chang, Yang, Jin-Young, Je Kyung Seong, Ko, Hyun-Jeong, Seo, Sang-Uk, Hyun-Jeong Ko, Jin-Young Yang, Hyungjun Yang, Seong, Je Kyung   +13 more
core   +1 more source

Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer

Immunology, Volume 178, Issue 3, Page 377-386, July 2026.
Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Alef Batista Bezerra Barros, Gabriel Augusto Leite, Arthur Gomes de Andrade, Maria Danielma dos Santos Reis, Luiz Henrique Agra Cavalcante‐Silva, Marvin Paulo Lins   +5 more
wiley   +1 more source

Studies on Functions of Peripheral Blood Lymphocytes in Patients with Hypergammaglobulinemia : With Reference to the PWM-induced Production of Immunoglobulins

, 1980
In order to study the mechanism of hypergammaglobulinemia from a point of view of T and B cell functions, the appearance rate of Ig-containing cells and the amount of Ig synthesized after stimulation of pokeweed mitogen （PWM） in the mixed culture of T ...
加藤, 康夫
core   +1 more source

Gingival and Periodontal Diseases and Conditions in Children and Adolescents: Consensus Report

Journal of Clinical Periodontology, Volume 53, Issue 7, Page 1068-1099, July 2026.
ABSTRACT Background The objectives of this Focused Workshop were to update the epidemiology, aetiology, risk factors, diagnosis and management of gingival and periodontal diseases and conditions in children and adolescents, and to explore the applicability of the 2018 Classification in children and adolescents.
Iain Chapple, Sotiria Gizani, Mariano Sanz, Dominique Declerck, Phoebus Madianos, Valerie Clerehugh, Monique Danser, Esti Davidovich, Janet Davies, Nikos Donos, Elisabeth Dursun, Elena Figuero, Filippo Graziani, Mervi Gursoy, Soren Jepsen, Clara Joseph, Moritz Kebschull, Norbert Kraemer, Tina Lambrinaki, Rodrigo López, David J. Manton, Joerg Meyle, Ana Molina, Lior Shapira, Cheryl Somani, Georgios Tsilingaridis, Svante Twetman, Nicola West, Biniyam Wondimu, Ferranti Wong, David Herrera   +30 more
wiley   +1 more source

A Case of Lethal Idiopathic Plasmacytic Lymphadenopathy with Polyclonal Hypergammaglobulinemia: A Medical Challenge for the Forensic Pathologist

, 2016
A rare case of lethal idiopathic plasmacytic lymphadenopathy (IPL) with polyclonal hyperimmunoglobulinemia with chronic renal failure is described. A 40-year-old woman who had suffered from upper airways disease was admitted to the Emergency Room with ...
Solarino B., Di Vella G., Tattoli L., Schiraldi O.   +3 more
core   +1 more source

Stage‐Dependent Transcriptional Reprogramming of B‐Cell Receptor Signaling and Antigen Presentation During Bovine Leukemia Virus–Driven Lymphomagenesis

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT Bovine leukemia virus (BLV), an oncogenic deltaretrovirus, establishes lifelong infection in cattle and induces enzootic bovine leukosis in a subset of animals following prolonged latency. Despite extensive evidence of immune dysregulation, stage‐specific transcriptional reprogramming of B cells, the primary viral reservoir remains ...
Mohammad Mehdi Akbarin, Zahra Farjami, Cecilia Rodríguez Murillo, Víctor David González‐Fernández, Gabriel Eduardo Acevedo‐Jiménez, Lucero de María Ávila‐De la Vega, Hugo Ramírez Álvarez   +6 more
wiley   +1 more source

Hyperferritinemia and hypergammaglobulinemia predict the treatment response to standard therapy in autoimmune hepatitis. [PDF]

PLoS ONE, 2017
Autoimmune hepatitis (AIH) is a chronic hepatitis with an increasing incidence. The majority of patients require life-long immunosuppression and incomplete treatment response is associated with a disease progression.
Richard Taubert, Matthias Hardtke-Wolenski, Fatih Noyan, Claudine Lalanne, Danny Jonigk, Jerome Schlue, Till Krech, Ralf Lichtinghagen, Christine S Falk, Verena Schlaphoff, Heike Bantel, Luigi Muratori, Michael P Manns, Elmar Jaeckel   +13 more
doaj   +1 more source

n Autopsy Case of Malignant Hemangicendotheliomatosis of Bone Marrow Accompanied by Hypergammaglobulinemia.

, 1968
An autopsy case of 25-year-old male who had complaints of anemia, remittent fever, pains referable to bones, emaciation, and jaundice is presented.
佐々木, 喬敏, 藤本, 輝夫, 池田, 成之, 福田, 守道, 小山, 隆三, 坂本, 真一   +5 more
core   +1 more source