CPT2 as a Convergent Node Linking Age-Associated Neuronal H3K27me3 Remodeling to Nicotinamide Mononucleotide (NMN)-Induced Expression Rescue in Metabolic Tissues. [PDF]
Cheung N.
europepmc +1 more source
ABSTRACT Drug Combinations offer increased therapeutic efficacy and reduced toxicity compared with single agents. Understanding a drug combination's mechanisms of action (MoA) can provide important insights into therapeutic efficacy. The MoA of many FDA‐approved drugs, however, often remains unclear.
Rui‐Sheng Wang +5 more
wiley +1 more source
P-selectin delineates conserved functional heterogeneity in early hematopoietic stem cell aging in humans and mice. [PDF]
Yang C +7 more
europepmc +1 more source
Tunable Fabrication of 2D‐Layered Magnesium Nanosilicates With Hemostatic Properties
Tunable 2D magnesium nanosilicates form bioactive protein coronas, support cellular internalization, and promote hemostatic activity. These nanoclays enable shear‐thinning gel formation and reduce clotting time and blood loss, highlighting their potential for wound‐management applications. Tunable fabrication of inorganic two‐dimensional (2D) nanoclays
Anna L. Keller +13 more
wiley +1 more source
Inequality measures of the generalized gamma distribution with a practicable application tool. [PDF]
Altun E, Gezer F, Alqifari HN.
europepmc +1 more source
Unveiling the “Gray Zone”: Characterizing Young People's Moderate STEM Identities
ABSTRACT Understanding how students identify with STEM (Science, Technology, Engineering, Mathematics) is crucial for fostering broader and more equitable participation within these fields. While existing research has focused on students who either strongly identify with STEM or disengage from it, this study explores the moderate STEM identities of ...
Carme Grimalt‐Álvaro +2 more
wiley +1 more source
Intracellular iron homeostasis-regulated epigenetic reprogramming contributes to -7/del(7q) leukemia. [PDF]
Zheng J +19 more
europepmc +1 more source
Abstract Accurate discharge estimation in hydroelectric canals is essential for turbine efficiency monitoring and operational decision‐making, yet conventional current‐meter methods provide no rigorous uncertainty quantification for the integrated discharge quantity.
Dominique Tapsoba, Xavier Emery
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RSMA-enabled satellite-terrestrial communication networks: Performance analysis. [PDF]
Nguyen HN, Nguyen QS, Nguyen TN.
europepmc +1 more source
Integrative Analysis Uncover the Effects and Multi‐Omics Features of Thigh Muscle Fat Infiltration
Thigh muscle fat infiltration (TMFI), estimated from MRI, is associated with increased mortality and diseases affecting multiple organ systems and mediates the effects of lifestyle factors on health. Multi‐omics analyses delineate the genetic, cellular, transcriptional, proteomic, and metabolic architecture of TMFI.
Yiwei Zhang +12 more
wiley +1 more source

