Results 191 to 200 of about 5,194,501 (290)

Quantitative proteomics reveals coordinated changes in the proteome during replicative senescence. [PDF]

Nat Commun
Da Silva Fernandes N, Kielisch F, Fulzele A, Karunanithi S, Gräf JF, Chen JX, Behl C, Ulrich HD, Beli P.   +8 more
europepmc   +1 more source

A synthetic community promotes macadamia growth via root‐microbe interactions and systemic plant responses

iMetaOmics, Volume 3, Issue 3, September 2026.
We employed an 18‐month pot experiment and an integrated multi‐omics approach to elucidate the potential mechanisms underlying synthetic community (SynCom)‐mediated macadamia growth promotion. SynCom inoculation enhanced soil nitrogen cycling and potential nutrient (e.g., iron) acquisition.
Xiaofang Yao, Qiumei Liu, Wenlin Wang, Qiujin Tan, Chunheng Zhou, Dejun Li   +5 more
wiley   +1 more source

Que/n-HA/PGCL microspheres orchestrate bone repair via context-dependent osteoimmune mechanisms: a transcriptomic dissection of direct and immune-mediated signaling. [PDF]

Front Immunol
Han C, Wang Q, Yang S, Ai Y, Liu Y, Song W, Yin W.   +6 more
europepmc   +1 more source

COL1A1+ Epithelial Cells Orchestrate VEGFA‐VEGFR Signaling in Endometritis Revealed by Single‐Cell Analysis

Journal of Clinical Laboratory Analysis, Volume 40, Issue 18, September 2026.
Single‐cell RNA‐seq of normal and endometritis endometrium shows reduced epithelial cells and fate divergence toward ferroptosis or ribosome/antigen‐presentation programs. COL1A1+ epithelial cells act as an AP‐1–driven hub that enhances VEGFA–VEGFR signaling and remodels the vascular microenvironment.
Chengzi Tian, Zaiyi Li
wiley   +1 more source

Dormancy exit correlates with CREB1 reactivation that is a potential target to overcome endocrine therapy resistance in ER⁺ breast cancer cells. [PDF]

iScience
Duan L, O'Hara KM, Maki CG.
europepmc   +1 more source

Integrated Single‐Cell RNA Sequencing and Untargeted Metabolomics Reveals β‐Elemene's Immune and Metabolic Modulation in Triple‐Negative Breast Cancer

MedComm – Oncology, Volume 5, Issue 3, September 2026.
In a 4T1 TNBC model, β‐elemene suppressed tumor growth and pulmonary metastasis. scRNA‐seq showed it remodeled the tumor microenvironment by reducing cancer‐associated fibroblasts, enhancing antigen presentation, and inhibiting pro‐tumorigenic ECM remodeling. Metabolomics revealed prostaglandin downregulation.
Zhiqiang Luo, Guohua Yu, Huixia Fan, Ruofan Guo, Jingqi Zheng, Chen Wang, Ruyi Jin, Junhui Zhou, Jian Yang   +8 more
wiley   +1 more source

Glucose-TOR-PDCB signaling restricts cell-to-cell communication through callose deposition. [PDF]

Sci Adv
Busche M, Runkel AM, Xu M, Klimpel KA, Menon S, Lund KM, Koch K, Chatterjee S, Alberts ER, Martinez RE, Scarpin MR, Brunkard JO.   +11 more
europepmc   +1 more source

Bias of Odds Ratio Estimate in Fisher's Exact Test

International Journal of Methods in Psychiatric Research, Volume 35, Issue 3, September 2026.
ABSTRACT Objectives The odds ratio estimate in Fisher's exact test can overestimate the parameter. A simple computer simulation can easily reveal the positive bias of the odds ratio estimate from Fisher's exact test. Bootstrap can facilitate bias correction for the odds ratio estimate.
Xiaofeng Steven Liu
wiley   +1 more source

Analytic posterior distribution and bayes factor for pearson partial correlations. [PDF]

Test (Madr)
Kucharský Š, Wagenmakers EJ, Bergh DVD, Ly A.   +3 more
europepmc   +1 more source

Systemic impact of intramuscular snake envenomation and intravenous immunoglobulin‐based antivenom treatment on murine plasma proteome and peptidome

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Snake envenomation remains a critical global public health challenge. In Brazil, the genus Bothrops is responsible for most accidents, typically resulting in coagulopathy, hemorrhage, and renal failure. Despite its clinical prevalence, the molecular mechanisms driving plasma protein disturbances remain poorly understood.
Bianca C. S. C. de Barros, Alison F. A. Chaves, Mariana S. L. C. Morone, Ana T. A. Sachetto, Marcelo L. Santoro, Oliver Schilling, Solange M. T. Serrano   +6 more
wiley   +1 more source