Results 211 to 220 of about 5,194,501 (290)

Multiscale analysis and functional validation of the cellular and genetic determinants of skeletal disease. [PDF]

Nat Genet
Chai RC, Lundberg M, Freudenthal B, Smith JT, Boughton AP, Zhang Y, Flynn KA, Frysz M, Corr AP, Khoo WH, Komla-Ebri D, Dack MRG, Guilfoyle SE, Logan JG, Butterfield NC, Leitch VD, Pollard AS, Mäkitie RE, Bradford N, Ramos-Mucci L, Vilas-Zornoza A, Chen Y, Yip RKH, Er J, Tan SZ, McDonald MM, Youlten SE, Sergio CM, Castro-Martinez A, Young SG, Skorokhodova E, Evans DM, Powell JE, de Leeuw CA, Ewing AD, Eisman JA, Blank RD, Phan TG, International Federation of Musculoskeletal Research Societies (IFMRS) Big Data Working Group, Lagendijk AK, Hawkins ED, Oh HL, McIntyre RE, Hessel EM, Taylor-King JP, Baldock PA, Duncan EL, Williams GR, Bassett JHD, Croucher PI, Kemp JP.   +50 more
europepmc   +1 more source

Impact of G‐CSF on Donor TCR Clonal Diversity and T Cell Function During Donor HSC Mobilisation

Cell Proliferation, Volume 59, Issue 9, September 2026.
In this study, we found that G‐CSF mobilisation caused a reduction in TCR clonal diversity and down‐regulation of T‐cell function in donors. This may be one of the reasons for the low incidence of GVHD mediated by G‐CSF after allo‐HSCT. Source: Created in BioRender. Li https://BioRender.com/otownki.
Xinye Li, Zhixi Chen, Jie Chen, Xingwei Zhang, Jiamian Zheng, Zirui Liu, Meixue Pan, Yue Li, Bo Yu, Shaohua Chen, Jing Lai, Xianfeng Zha, Liye Zhong, Yikai Zhang, Yangqiu Li   +14 more
wiley   +1 more source

Diabetes-associated MYT1 and ST18 genes regulate human beta cell insulin secretion and survival via other diabetes risk genes. [PDF]

Diabetologia
Hu R, Hamilton N, Wang Y, Tong X, Yagan M, Dadi PK, Harmelink C, Doss TD, Liu J, Xu Y, Simmons AJ, Lau KS, Stein R, Balamurugan AN, Kaverina I, Coate KC, Jacobson DA, Liu Q, Gu G.   +18 more
europepmc   +1 more source

Harnessing Metabolic Priming to Engineer Human Nucleus Pulposus Macromass Overcoming Scalability‐Phenotype Tradeoff

Cell Proliferation, Volume 59, Issue 9, September 2026.
Human platelet lysate acts as a metabolic primer for hNPCs, enhancing fatty acid oxidation to drive proliferation while preserving phenotype. This enables construction of high‐quality, large‐size macromasses without necrotic defects, demonstrating exceptional efficacy in repairing degenerated discs in situ and providing a novel paradigm for ...
Yingbo Wang, Ou Hu, Jian Wu, Sha Huang, Peng Lin, Pulin Yan, Yangyang Li, Huaijian Jin, Yutong Wu, Jun Zhu, Jungang Pu, Bo Hu, Jian He, Yibo Gan, Peng Liu   +14 more
wiley   +1 more source

A note on a generalized double series. [PDF]

PLoS One
Reynolds R.
europepmc   +1 more source

Quantifying the Evolutionary Potential for Delta Smelt Persistence in a Warming Habitat

Evolutionary Applications, Volume 19, Issue 9, September 2026.
ABSTRACT Long‐term persistence of managed species will depend, in part, on whether the species harbors the physiological or genetic potential to adjust to warming temperatures, and whether relevant genetic variation is modified by management practices.
Joanna S. Griffiths, Amanda J. Finger, Md. Moshiur Rahman, Brittany E. Davis, Tien‐Chieh Hung, Nann A. Fangue, Andrew Whitehead   +6 more
wiley   +1 more source

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

The FEBS Journal, Volume 293, Issue 17, Page 5340-5362, September 2026.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior, Maria Anastasia Doumani, Hao Fu, Jelle van den Bor, Olof Idevall‐Hagren, Aristidis Moustakas   +5 more
wiley   +1 more source

Explicit minimisers for anisotropic Riesz energies. [PDF]

Calc Var Partial Differ Equ
Frank RL, Mateu J, Mora MG, Rondi L, Scardia L, Verdera J.   +5 more
europepmc   +1 more source

Coniferyl aldehyde from the phenylpropanoid pathway targets pyruvate kinase in Dactylobotrys graminicola to confer sheath rot resistance in hulless barley

Journal of Integrative Plant Biology, Volume 68, Issue 9, Page 3490-3507, September 2026.
Hulless barley resists the newly identified sheath rot disease caused by the necrotrophic fungal pathogen Dactylobotrys graminicola by releasing coniferyl aldehyde, a natural compound that disrupts energy production in the fungus. ABSTRACT Dactylobotrys graminicola (Dgr), a necrotrophic fungal pathogen, has recently been identified as the causative ...
Haowen Zheng, Liyifan Chen, Jianguo Wei, Yuandi Xu, Rangrang Chen, Yu Li, Yan Liu, Jiahui Yan, Lu Hou, Yiliang Chen, Zhensheng Kang, Haifeng Zhang, Qiang Yao   +12 more
wiley   +1 more source

Prenatal neural network organization and later executive function development. [PDF]

Dev Cogn Neurosci
Massera A, Menu I, Ji L, Lee C, Sacasa M, Trentacosta CJ, Thomason ME.   +6 more
europepmc   +1 more source