Results 211 to 220 of about 107,962 (311)

Cellular microenvironment of erythropoietin‐producing cells in hypoxic and injured mouse kidneys

Experimental Physiology, EarlyView.
Abstract The main sources of circulating erythropoietin (Epo) in the adult are kidney Norn cells, a recently identified interstitial cell type capable of becoming renal Epo‐producing (REP) cells following a local decrease in tissue oxygenation. REP cells are restricted to small clusters in the corticomedullary border region, suggesting that their ...
Olga M. Lempke, Thomas Knöpfel, Stellor Nlandu Khodo, Roland H. Wenger   +3 more
wiley   +1 more source

Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes. [PDF]

Nat Commun
Uusküla-Reimand L, Lee CA, Oh RH, Klein ZP, Adler N, Akhtar Alvi S, Langille E, Pasini E, Cheng KCL, Serafimova E, Abd-Rabbo D, Hou H, Tsai R, Bhat M, Schramek D, Wilson MD, Reimand J.   +16 more
europepmc   +1 more source

C‐X‐C chemokine receptor CXCR4 mediates diurnal changes in the aggregation and dispersion of CD8+ T cells within the tumor microenvironment

International Journal of Cancer, Volume 158, Issue 6, Page 1740-1754, 15 March 2026.
What's new? In addition to governing daily variations in biological activity, the circadian clock regulates immune cell migration into tumors. Whether this influence extends to immune cell localization within the tumor microenvironment (TME) is unknown. Here, using cell and animal models, the authors investigated immune cell distribution within the TME
Akito Tsuruta, Marina Fujimoto, Yasuha Hiraoka, Aoi Taniguchi, Yuki Shiiba, Takuto Inoki, Tomoaki Yamauchi, Yuya Yoshida, Naoya Matsunaga, Shigehiro Ohdo, Satoru Koyanagi   +10 more
wiley   +1 more source

Analytic study and statistical enforcement of extended beta functions imposed by Mittag-Leffler and Hurwitz-Lerch Zeta functions. [PDF]

MethodsX
Abdulnabi FF, Al-Janaby HF, Ghanim F.
europepmc   +1 more source

A comprehensive review of cluster methods for drug–drug interaction network

Quantitative Biology, Volume 14, Issue 1, March 2026.
Abstract The detection of drug–drug interaction (DDI) is crucial to the rational use of drug combinations. Experimentally, DDI detection is time‐consuming and laborious. Currently, researchers have developed a variety of computational methods to predict DDI.
Shuyuan Cao, Guixia Liu, Xiangrun Zhou, Ji Lv   +3 more
wiley   +1 more source

Egr1 is a sex-dependent regulator of neuronal chromatin, structural plasticity, and behaviour. [PDF]

Nat Commun
Rocks D, Demarchi L, Ouldibbat L, Purisic E, Cham H, Gallo EF, Greally JM, Suzuki M, Kundakovic M.   +8 more
europepmc   +1 more source

Toward Psychometric Learning Analytics: Augmenting the Urnings Algorithm with Response Times

Journal of Educational Measurement, Volume 63, Issue 1, Spring 2026.
Abstract Adaptive learning systems (ALS) aim to tailor the educational material to match the student's needs, ultimately improving the learning outcomes. An ALS dynamically adjust the level of practice based on the student's ability; therefore, obtaining accurate ability estimates is crucial.
Bence Gergely, Maria Bolsinova
wiley   +1 more source

Drug discovery for chemotherapeutic resistance based on pathway-responsive gene sets and its application in breast cancer. [PDF]

Front Bioinform
Feng D, Hao J, Li L, Chen J, Liu X, Zhang R, Han H, Li T, Wang X, Li X, Yu L, Li B, Li J, Wang L.   +13 more
europepmc   +1 more source

Multiple zeta values and connection formulas of Gauss's hypergeometric functions (Recent Trends in Microlocal Analysis)

, 2005
Takashi Aoki, Yasuo Ohno
openalex   +1 more source

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

Advanced Science, Volume 13, Issue 7, 3 February 2026.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo, Junhui Chen, Yehai An, Kun Meng, Wei Zhou, Wenhui Li, Jing Liu, Wentong Zhao, Weiyi He, Ting Cao, Jingnan Huang, Sha Feng, Shiguang Yang, Hongling Hu, Jiaxian Liao, Hengkai He, Mingjing Hao, Qian Zhang, Jigang Wang, Yue Gao   +19 more
wiley   +1 more source