Results 71 to 80 of about 103,034 (331)

Cathepsin K Aggravates Pulmonary Fibrosis Through Promoting Fibroblast Glutamine Metabolism and Collagen Synthesis

Advanced Science, EarlyView.
CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen, Xiaoxiao Meng, Yong Zhu, Dapeng Wang, Mengmeng Wang, Ziyuan Wang, Xue Tian, Jiaxiang Zhang, Zhiying Yue, Zhengfeng Yang, Ruilan Wang   +10 more
wiley   +1 more source

A relativistic hypergeometric function [PDF]

Journal of Computational and Applied Mathematics, 2005
AbstractWe survey our work on a function generalizing 2F1. This function is a joint eigenfunction of four Askey–Wilson-type hyperbolic difference operators, reducing to the Askey–Wilson polynomials for certain discrete values of the variables. It is defined by a contour integral generalizing the Barnes representation of 2F1.
openaire   +1 more source

De Novo Reconstruction of 3D Human Facial Images from DNA Sequence

Advanced Science, EarlyView.
This study introduces Difface, a novel deep‐learning model for reconstructing 3D facial images only from DNA data. By integrating transformer networks, spiral convolutions, and a diffusion model, Difface directly aligns high‐dimensional SNP data with 3D facial structures.
Mingqi Jiao, Jiarui Li, Bingxu Zhong, Siyuan Du, Shuning Li, Manfei Zhang, Qibin Zhang, Zhongming Liang, Fan Liu, Chunman Zuo, Sijia Wang, Luonan Chen   +11 more
wiley   +1 more source

Hypoglycemia Induces Diabetic Macrovascular Endothelial Dysfunction via Endothelial Cell PANoptosis, Macrophage Polarization, and VSMC Fibrosis

Advanced Science, EarlyView.
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo, Yuce Peng, Guozhi Zhao, Zhesheng Cheng, Minghao Luo, Dingyi Lv, Shuting Chang, Na Li, Yanyao Huang, Xunjia Li, An He   +10 more
wiley   +1 more source

Aspects of elliptic hypergeometric functions [PDF]

, 2013
General elliptic hypergeometric functions are defined by elliptic hypergeometric integrals. They comprise the elliptic beta integral, elliptic analogues of the Euler-Gauss hypergeometric function and Selberg integral, as well as elliptic extensions of ...
Spiridonov, V. P.
core  

Spatial boundary problem with the Dirichlet-Neumann condition for a singular elliptic equation

, 2012
The present work devoted to the finding explicit solution of a boundary problem with the Dirichlet-Neumann condition for elliptic equation with singular coefficients in a quarter of ball. For this aim the method of Green's function have been used. Since,
Agostinelli, Appell, Barantsev, Barros-Neto, Bicadze, Bitsadze, E.T. Karimov, Erdelyi, Frankl, Hasanov, Hasanov, Karimov, M.S. Salakhitdinov, Nahus̆ev, Nazipov, Nieto, Olevskiĭ, Protter, Rassias, Salakhitdinov, Semerdjieva, Serbina, Smirnov, Tricomi, Urinov, Wen, Wen   +26 more
core   +1 more source

Disruption of ARID1B Recruitment to the Nuclear Pore Complex as a New Anticancer Therapeutic Strategy

Advanced Science, EarlyView.
This study identifies ARID1B as a chromatin‐bound driver of tumor growth in TNBC. ARID1B impairs ARID1A function and directly activates oncogenic programs through SWI/SNF remodeling. Its nuclear localization, mediated by the KPNA2–KPNB1–RANBP2 import machinery, is essential for its tumor‐promoting activity.
Olena Odnokoz, Anupam Banerjee, Xin Cui, Lidan Zeng, Amad Uddin, Christopher Li, Yueming Zhu, Mengyuan Zhang, Xiaodong Lu, Nagendra S. Yarla, Lu Wang, Jindan Yu, Jonathan C. Zhao, Ivet Bahar, Yong Wan   +14 more
wiley   +1 more source

Several properties of hypergeometric Bernoulli numbers

Journal of Inequalities and Applications, 2019
In this paper, we give several characteristics of hypergeometric Bernoulli numbers, including several identities for hypergeometric Bernoulli numbers which the convergents of the continued fraction expansion of the generating function of the ...
Miho Aoki, Takao Komatsu, Gopal Krishna Panda   +2 more
doaj   +1 more source

Modular forms, Schwarzian conditions, and symmetries of differential equations in physics

, 2017
We give examples of infinite order rational transformations that leave linear differential equations covariant. These examples are non-trivial yet simple enough illustrations of exact representations of the renormalization group.
Abdelaziz, Y., Maillard, J. -M.
core   +3 more sources

A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma

Advanced Science, EarlyView.
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao, Zhen Li, Ming‐Jie Zhao, Shu‐Ying Li, Qing Xia, Shuoyu Xu, Yu Zhang, Yi Wang, Fang Li, Yu‐Ling Liu, Yun‐Hui Guo, Ruo‐Xi Xu, Han Zhou, Hong Zhou, Wen‐Wen Ding, Yong‐Chen Wang, Yanying Miao, Zhongfeng Wang   +17 more
wiley   +1 more source