Results 141 to 150 of about 98,219 (279)

Comparison of Three Sympatric Desert Lizards: Digestive Tract Structure, Digestive Enzyme Activities, Gut Microbiota, and Metabolites

open access: yesIntegrative Zoology, EarlyView.
We performed 16S rDNA sequencing and metabolite profiling for three sympatric lizard species—Teratoscincus roborowskii, Phrynocephalus axillaris, and Eremias roborowskii—and compared their goblet cell and enzyme activities in the digestive tract. Our study suggests that the dietary niche may promote divergence or convergence of microbiota across host ...
Yi Yang, Ziyi Wang, Ruichen Wu
wiley   +1 more source

Cellular Stress, Inflammation and Barrier Damage in Gut Epithelial Cells Caused by Aspartame

open access: yesAllergy, EarlyView.
This study shows that aspartame, at dietary‐relevant doses, induces cytotoxicity, cellular distress associated with endoplasmic reticulum stress, oxidative stress, DNA replication and repair mechanism disturbance culminating in epithelial barrier damage.
Yagiz Pat   +16 more
wiley   +1 more source

Certain transformations of basic hypergeometric functions of two variables

open access: yesLe Matematiche, 1989
In this note the authors derive three transformations for the basic hypergeometric functions of two variables by making use of certain known summations formula.
R. K. Sakena, R. Kumar
doaj  

Pharmacological inhibition of hydroxysteroid 11‐beta dehydrogenase type 1 (11‐βHSD1) after myocardial infarction preserves cardiac function in a translational mini‐pig model

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi   +19 more
wiley   +1 more source

PHGDH Orchestrates Cell Cycle Progression to Drive Cardiomyocyte Proliferation and Myocardial Regeneration via TGF‐β/Smad Signalling Pathway

open access: yesCell Proliferation, EarlyView.
PHGDH promoted cardiomyocyte proliferation and myocardial regeneration via cell cycle and TGF‐β/Smad signalling pathways during cardiac repair. Moreover, PHGDH benefits cardiac repair and cardiomyocyte proliferation in mammalian mice following MI. ABSTRACT The mature mammalian heart has limited ability for self‐repair and regeneration.
Han Zhang   +6 more
wiley   +1 more source

Do temporary changes in earnings caused by mean reversion affect firms’ refinancing decisions?

open access: yesJournal of Financial Research, EarlyView.
Abstract We develop a dynamic two‐stage trade‐off model with refinancing when earnings are mean reverting. Our model predicts a negative relation between profitability and leverage at refinancing due to conservative debt increases. With multiple rounds of refinancing, the leverage–profitability relation may turn positive when firms have substantial ...
Elettra Agliardi   +3 more
wiley   +1 more source

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