Results 141 to 150 of about 1,745,713 (225)

From Arabidopsis to Crop Prediction: Enrichment and Limitations of Tree‐Based SHAP for Marker Prioritization in Plant Breeding

Plant Breeding, EarlyView.
ABSTRACT Genomic prediction is widely used in plant breeding, but feature‐attribution scores from predictive models are sometimes interpreted as evidence for trait‐associated or causal loci. We evaluated whether global SHapley Additive exPlanations (SHAP) from XGBoost and LightGBM prioritize markers or genomic windows enriched for signals from mixed ...
Francisco Orts
wiley   +1 more source

Extensive horizontal gene transfer drives microbial adaptation and diversification in Kermadec Trench hadal microbiomes. [PDF]

Nat Commun
Liu P, Lv Y, Zhang Y, Wang Y, Zhu K, Cao Z, Dong L, Xiao X, Pan Y, Li J.   +9 more
europepmc   +1 more source

TREM2+ macrophages accumulate in childhood IgA nephropathy and soluble TREM2 represents a reliable non‐invasive biomarker

Experimental Physiology, EarlyView.
Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu, Xuan Gang, Jingjing Wang, Guoping Huang, Qiuyu Li, Weizhong Gu, Haidong Fu, Jianhua Mao   +7 more
wiley   +1 more source

Certain Hypergeometric Generating Relations Using Gould’s Identity and Their Generalizations

Asia Pacific Journal of Mathematics, 2018
M.I. Qureshi, Sulakshana Bajaj
doaj   +1 more source

Cross-Cohort Transcriptomic Prioritization and Chemical-Provenance Assessment of Asthma Airway-Brushing Genes Overlapping HERB-Annotated <i>Scrophularia ningpoensis</i> Targets. [PDF]

Int J Mol Sci
Zou J, Tian X, Wang S, Sun Y.
europepmc   +1 more source

Biofilm Development and Stage‐Specific Multi‐Omics Analysis of Metschnikowia bicuspidata Associated With Milky Disease in the Eriocheir sinensis

Aquaculture, Fish and Fisheries, Volume 6, Issue 6, December 2026.
ABSTRACT Metschnikowia bicuspidata, the causative agent of milky disease in the Chinese mitten crab (Eriocheir sinensis), is an important aquatic pathogenic yeast in freshwater aquaculture. However, the developmental characteristics and molecular regulation of its biofilm formation remain poorly understood.
Yitong Deng, Yue Wang, Zheyi Lei, Junchi Xu, Jie Bao, Hongbo Jiang   +5 more
wiley   +1 more source

Diabetes-associated MYT1 and ST18 genes regulate human beta cell insulin secretion and survival via other diabetes risk genes. [PDF]

Diabetologia
Hu R, Hamilton N, Wang Y, Tong X, Yagan M, Dadi PK, Harmelink C, Doss TD, Liu J, Xu Y, Simmons AJ, Lau KS, Stein R, Balamurugan AN, Kaverina I, Coate KC, Jacobson DA, Liu Q, Gu G.   +18 more
europepmc   +1 more source

DNA Methylation and Transcriptomic Profiles of Wilms Tumour Reveal New Deregulated Genes and Epigenetic Processes Relevant for Tumour Stratification and Management

International Journal of Cancer, Volume 159, Issue 11, Page 2736-2754, 1 December 2026.
ABSTRACT Wilms Tumour (WT), the most common kidney cancer in children, presents features of altered kidney development and frequently exhibits molecular alterations at the 11p15.5 imprinted locus, affecting the IGF2 and H19 genes, which contribute to tumour growth and predisposition.
Abu Saadat, Francesco Cecere, Federica Rossetti, Laura Pignata, Emilia D'Angelo, Carlo Giaccari, Gaetano Verde, Paola Quarello, Franca Fagioli, Josep Roma, Manel Esteller, Enrique de Álava, Flavia Cerrato, Andrea Riccio, Angela Sparago   +14 more
wiley   +1 more source

paraORA: GPU-Accelerated Exact Over-Representation Analysis for Repeated Queries of Large Gene-Set Libraries. [PDF]

Biology (Basel)
Wu Z, Zhang Z, Feng W, Sun J, Liu Z, Wang G, Liu Y.   +6 more
europepmc   +1 more source

The novel regulatory influence of Argonaute 1 on messenger RNA 5‐methylcytosine modification in Arabidopsis thaliana

The Plant Genome, Volume 19, Issue 4, December 2026.
Abstract 5‐Methylcytidine (m5C) modifications play a critical role in RNA metabolism. TRM4B (tRNA‐specific methytransferase 4B) is the only known component of the plant m5C machinery that mediates mRNA (messenger RNA) methylation. To date, no regulators governing site‐specific m5C modifications have been identified, apart from several degenerated ...
Zedi Feng, Xiu Yin, Zhifang Jiang, Jia Yao, Yiling Dong, Xiaoxia Ma, Yijun Meng   +6 more
wiley   +1 more source